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Lukasz Swiech
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CRISPR-Cas9 knockin mice for genome editing and cancer modeling
RJ Platt, S Chen, Y Zhou, MJ Yim, L Swiech, HR Kempton, JE Dahlman, ...
Cell 159 (2), 440-455, 2014
19532014
In vivo interrogation of gene function in the mammalian brain using CRISPR-Cas9
L Swiech, M Heidenreich, A Banerjee, N Habib, Y Li, J Trombetta, M Sur, ...
Nature biotechnology 33 (1), 102-106, 2015
8822015
Div-Seq: Single-nucleus RNA-Seq reveals dynamics of rare adult newborn neurons
N Habib, Y Li, M Heidenreich, L Swiech, I Avraham-Davidi, JJ Trombetta, ...
Science 353 (6302), 925-928, 2016
5382016
Role of mTOR in physiology and pathology of the nervous system
L Swiech, M Perycz, A Malik, J Jaworski
Biochimica et Biophysica Acta (BBA)-Proteins and Proteomics 1784 (1), 116-132, 2008
4142008
Mammalian target of rapamycin complex 1 (mTORC1) and 2 (mTORC2) control the dendritic arbor morphology of hippocampal neurons
M Urbanska, A Gozdz, LJ Swiech, J Jaworski
Journal of Biological Chemistry 287 (36), 30240-30256, 2012
1582012
The dissection of transcriptional modules regulated by various drugs of abuse in the mouse striatum
M Piechota, M Korostynski, W Solecki, A Gieryk, M Slezak, W Bilecki, ...
Genome biology 11, 1-21, 2010
1582010
Optimized crispr-cas double nickase systems, methods and compositions for sequence manipulation
F Zhang, P Hsu, C Lin, RAN Fei, L SWIECH
1272014
Delivery, use and therapeutic applications of the CRISPR-Cas systems and compositions for targeting disorders and diseases using viral components
F Zhang, L Cong, RAN Fei, M Heidenreich, L Swiech
US Patent 10,946,108, 2021
1242021
CLIP-170 and IQGAP1 cooperatively regulate dendrite morphology
L Swiech, M Blazejczyk, M Urbanska, P Pietruszka, BR Dortland, ...
Journal of Neuroscience 31 (12), 4555-4568, 2011
1082011
Delivery, engineering and optimization of systems, methods and compositions for targeting and modeling diseases and disorders of post mitotic cells
F Zhang, M Heidenreich, L Swiech
US Patent App. 14/971,169, 2016
1052016
Methods for determining spatial and temporal gene expression dynamics in single cells
A Regev, F Zhang, N Habib, Y Li, M Heidenreich, L Swiech, B Anindita, ...
US Patent App. 16/087,036, 2019
862019
Selective FcγR co-engagement on APCs modulates the activity of therapeutic antibodies targeting T cell antigens
JD Waight, D Chand, S Dietrich, R Gombos, T Horn, AM Gonzalez, ...
Cancer Cell 33 (6), 1033-1047. e5, 2018
792018
CD44 regulates dendrite morphogenesis through Src tyrosine kinase-dependent positioning of the Golgi
A Skupien, A Konopka, PI Trzaskoma, J Labus, A Gorlewicz, L Swiech, ...
Journal of Cell Science 127 (23), 5038-5051, 2014
502014
Cyr61, a matricellular protein, is needed for dendritic arborization of hippocampal neurons
AR Malik, M Urbanska, A Gozdz, LJ Swiech, A Nagalski, M Perycz, ...
Journal of Biological Chemistry 288 (12), 8544-8559, 2013
452013
Developmental plasticity of the dendritic compartment: focus on the cytoskeleton
M Urbanska, L Swiech, J Jaworski
Synaptic Plasticity: Dynamics, Development and Disease, 265-284, 2012
432012
Expression of Ttyh1, a member of the Tweety family in neurons in vitro and in vivo and its potential role in brain pathology
M Stefaniuk, L Swiech, J Dzwonek, K Lukasiuk
Journal of neurochemistry 115 (5), 1183-1194, 2010
392010
Delivery, use and therapeutic applications of the CRISPR-Cas systems and compositions for genome editing
L Cong, DBT Cox, M Heidenreich, RJ Platt, L Swiech, F Zhang
US Patent 11,407,985, 2022
382022
Accumulation and dynamics of proteins of the MCM family during mouse oogenesis and the first embryonic cell cycle
L Swiech, K Kisiel, R Czolowska, M Zientarski, E Borsuk
International Journal of Developmental Biology 51 (4), 283, 2007
212007
Tuberous sclerosis complex neuropathology requires glutamate-cysteine ligase
AR Malik, E Liszewska, A Skalecka, M Urbanska, AM Iyer, LJ Swiech, ...
Acta neuropathologica communications 3, 1-13, 2015
192015
mTOR w fizjologii i patologii układu nerwowego
M Perycz, Ł Świech, A Malik, J Jaworski, PNM i Komórkowej
Postępy Biol. Kom 34, 511-525, 2007
11*2007
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