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Jared Churko
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Chemically defined generation of human cardiomyocytes
PW Burridge, E Matsa, P Shukla, ZC Lin, JM Churko, AD Ebert, F Lan, ...
Nature methods 11 (8), 855-860, 2014
16012014
High-throughput screening of tyrosine kinase inhibitor cardiotoxicity with human induced pluripotent stem cells
A Sharma, PW Burridge, WL McKeithan, R Serrano, P Shukla, N Sayed, ...
Science translational medicine 9 (377), eaaf2584, 2017
3432017
Identification of a new modulator of the intercalated disc in a zebrafish model of arrhythmogenic cardiomyopathy
A Asimaki, S Kapoor, E Plovie, A Karin Arndt, E Adams, ZZ Liu, CA James, ...
Science translational medicine 6 (240), 240ra74-240ra74, 2014
2712014
Patient-specific and genome-edited induced pluripotent stem cell–derived cardiomyocytes elucidate single-cell phenotype of Brugada syndrome
P Liang, K Sallam, H Wu, Y Li, I Itzhaki, P Garg, Y Zhang, V Termglichan, ...
Journal of the American College of Cardiology 68 (19), 2086-2096, 2016
2202016
Epigenetic regulation of phosphodiesterases 2A and 3A underlies compromised β-adrenergic signaling in an iPSC model of dilated cardiomyopathy
H Wu, J Lee, LG Vincent, Q Wang, M Gu, F Lan, JM Churko, KI Sallam, ...
Cell stem cell 17 (1), 89-100, 2015
1912015
Overview of high throughput sequencing technologies to elucidate molecular pathways in cardiovascular diseases
JM Churko, GL Mantalas, MP Snyder, JC Wu
Circulation research 112 (12), 1613-1623, 2013
1862013
iPSC-derived cardiomyocytes reveal abnormal TGF-β signalling in left ventricular non-compaction cardiomyopathy
K Kodo, SG Ong, F Jahanbani, V Termglinchan, K Hirono, ...
Nature cell biology 18 (10), 1031-1042, 2016
1772016
Defining human cardiac transcription factor hierarchies using integrated single-cell heterogeneity analysis
JM Churko, P Garg, B Treutlein, M Venkatasubramanian, H Wu, J Lee, ...
Nature communications 9 (1), 4906, 2018
1702018
Transcriptome profiling of patient-specific human iPSC-cardiomyocytes predicts individual drug safety and efficacy responses in vitro
E Matsa, PW Burridge, KH Yu, JH Ahrens, V Termglinchan, H Wu, C Liu, ...
Cell stem cell 19 (3), 311-325, 2016
1652016
Human induced pluripotent stem cell–derived cardiomyocytes as an in vitro model for coxsackievirus B3–induced myocarditis and antiviral drug screening platform
A Sharma, C Marceau, R Hamaguchi, PW Burridge, K Rajarajan, ...
Circulation research 115 (6), 556-566, 2014
1602014
Activation of PDGF pathway links LMNA mutation to dilated cardiomyopathy
J Lee, V Termglinchan, S Diecke, I Itzhaki, CK Lam, P Garg, E Lau, ...
Nature 572 (7769), 335-340, 2019
1572019
Pannexin1 and pannexin3 delivery, cell surface dynamics, and cytoskeletal interactions
R Bhalla-Gehi, S Penuela, JM Churko, Q Shao, DW Laird
Journal of Biological Chemistry 285 (12), 9147-9160, 2010
1432010
Implications of pannexin 1 and pannexin 3 for keratinocyte differentiation
SJ Celetti, KN Cowan, S Penuela, Q Shao, J Churko, DW Laird
Journal of cell science 123 (8), 1363-1372, 2010
1272010
Loss of pannexin 1 attenuates melanoma progression by reversion to a melanocytic phenotype
S Penuela, L Gyenis, A Ablack, JM Churko, AC Berger, DW Litchfield, ...
Journal of Biological Chemistry 287 (34), 29184-29193, 2012
1242012
Characterization of the molecular mechanisms underlying increased ischemic damage in the aldehyde dehydrogenase 2 genetic polymorphism using a human …
AD Ebert, K Kodo, P Liang, H Wu, BC Huber, J Riegler, J Churko, J Lee, ...
Science translational medicine 6 (255), 255ra130-255ra130, 2014
1182014
VEGF-C and aortic cardiomyocytes guide coronary artery stem development
HI Chen, A Poduri, H Numi, R Kivela, P Saharinen, AS McKay, B Raftrey, ...
The Journal of clinical investigation 124 (11), 4899-4914, 2014
1132014
Generation of human iPSCs from human peripheral blood mononuclear cells using non-integrative Sendai virus in chemically defined conditions
JM Churko, PW Burridge, JC Wu
Cellular Cardiomyoplasty: Methods and Protocols, 81-88, 2013
932013
Novel codon-optimized mini-intronic plasmid for efficient, inexpensive and xeno-free induction of pluripotency
S Diecke, J Lu, J Lee, V Termglinchan, NG Kooreman, PW Burridge, ...
Scientific reports 5 (1), 8081, 2015
812015
MMP inhibitors attenuate doxorubicin cardiotoxicity by preventing intracellular and extracellular matrix remodelling
BYH Chan, A Roczkowsky, WJ Cho, M Poirier, C Sergi, V Keschrumrus, ...
Cardiovascular Research 117 (1), 188-200, 2021
792021
Assessment of the radiation effects of cardiac CT angiography using protein and genetic biomarkers
PK Nguyen, WH Lee, YF Li, WX Hong, S Hu, C Chan, G Liang, I Nguyen, ...
Cardiovascular Imaging 8 (8), 873-884, 2015
792015
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