Follow
Alistair J. Henry
Alistair J. Henry
Other namesAlistair Henry
UCB
Verified email at ucb.com
Title
Cited by
Cited by
Year
Two doses of sclerostin antibody in cynomolgus monkeys increases bone formation, bone mineral density, and bone strength
MS Ominsky, F Vlasseros, J Jolette, SY Smith, B Stouch, G Doellgast, ...
Journal of Bone and Mineral Research 25 (5), 948-959, 2010
5402010
Structure and interactions of the human programmed cell death 1 receptor
X Cheng, V Veverka, A Radhakrishnan, LC Waters, FW Muskett, ...
Journal of Biological Chemistry 288 (17), 11771-11785, 2013
3502013
Characterization of the structural features and interactions of sclerostin
V Veverka, AJ Henry, PM Slocombe, A Ventom, B Mulloy, FW Muskett, ...
Journal of Biological Chemistry 284 (16), 10890-10900, 2009
2872009
The crystal structure of IgE Fc reveals an asymmetrically bent conformation
T Wan, RL Beavil, SM Fabiane, AJ Beavil, MK Sohi, M Keown, RJ Young, ...
Nature immunology 3 (7), 681-686, 2002
2132002
Sclerostin-binding antibody
C Paszty, MK Robinson, K Graham, AJ Henry, KS Hoffmann, J Latham, ...
US Patent 7,592,429, 2009
1592009
Participation of the N-terminal region of Cε3 in the binding of human IgE to its high-affinity receptor FcεRI
AJ Henry, JPD Cook, JM McDonnell, GA Mackay, J Shi, BJ Sutton, ...
Biochemistry 36 (50), 15568-15578, 1997
1421997
The structure of the IgE Cɛ2 domain and its role in stabilizing the complex with its high-affinity receptor FcɛRIα
JM McDonnell, R Calvert, RL Beavil, AJ Beavil, AJ Henry, BJ Sutton, ...
Nature structural biology 8 (5), 437-441, 2001
1182001
Dynamics of intact immunoglobulin G explored by drift‐tube ion‐mobility mass spectrometry and molecular modeling
KJ Pacholarz, M Porrini, RA Garlish, RJ Burnley, RJ Taylor, AJ Henry, ...
Angewandte Chemie International Edition 53 (30), 7765-7769, 2014
1112014
Upregulation of FcϵRI on human basophils by IgE antibody is mediated by interaction of IgE with FcϵRI
D MacGlashan Jr, LM Lichtenstein, J McKenzie-White, K Chichester, ...
Journal of allergy and clinical immunology 104 (2), 492-498, 1999
1061999
Epitopes
M Robinson, A Henry, A Lawson, H Lu, C Paszty, K Hoffmann, J Latham, ...
US Patent App. 11/410,540, 2007
1042007
A tumor-associated β1 integrin mutation that abrogates epithelial differentiation control
RD Evans, VC Perkins, A Henry, PE Stephens, MK Robinson, FM Watt
The Journal of cell biology 160 (4), 589-596, 2003
982003
Crystal structure of IgE bound to its B-cell receptor CD23 reveals a mechanism of reciprocal allosteric inhibition with high affinity receptor FcεRI
B Dhaliwal, D Yuan, MOY Pang, AJ Henry, K Cain, A Oxbrow, ...
Proceedings of the National Academy of Sciences 109 (31), 12686-12691, 2012
972012
Discovery and characterization of olokizumab: a humanized antibody targeting interleukin-6 and neutralizing gp130-signaling
S Shaw, T Bourne, C Meier, B Carrington, R Gelinas, A Henry, ...
MAbs 6 (3), 773-781, 2014
962014
Characterization of the interaction of sclerostin with the low density lipoprotein receptor-related protein (LRP) family of Wnt co-receptors
G Holdsworth, P Slocombe, C Doyle, B Sweeney, V Veverka, K Le Riche, ...
Journal of Biological Chemistry 287 (32), 26464-26477, 2012
942012
Identification of contact residues in the IgE binding site of human FcεRIα
JPD Cook, AJ Henry, JM McDonnell, RJ Owens, BJ Sutton, HJ Gould
Biochemistry 36 (50), 15579-15588, 1997
911997
Automated protein–ligand interaction screening by mass spectrometry
HJ Maple, RA Garlish, L Rigau-Roca, J Porter, I Whitcombe, CE Prosser, ...
Journal of Medicinal Chemistry 55 (2), 837-851, 2012
812012
Allosteric mechanism of action of the therapeutic anti-IgE antibody omalizumab
AM Davies, EG Allan, AH Keeble, J Delgado, BP Cossins, AN Mitropoulou, ...
Journal of Biological Chemistry 292 (24), 9975-9987, 2017
732017
Engineering an improved IgG4 molecule with reduced disulfide bond heterogeneity and increased Fab domain thermal stability
SJ Peters, CM Smales, AJ Henry, PE Stephens, S West, DP Humphreys
Journal of Biological Chemistry 287 (29), 24525-24533, 2012
732012
Alternative antibody Fab′ fragment PEGylation strategies: combination of strong reducing agents, disruption of the interchain disulphide bond and disulphide engineering
DP Humphreys, SP Heywood, A Henry, L Ait-Lhadj, P Antoniw, ...
Protein Engineering, Design & Selection 20 (5), 227-234, 2007
692007
Secretion of recombinant human IgE-Fc by mammalian cells and biological activity of glycosylation site mutants
RJ Young, RJ Owens, GA Mackay, CMW Chan, J Shi, M Hide, DM Francis, ...
Protein Engineering, Design and Selection 8 (2), 193-199, 1995
691995
The system can't perform the operation now. Try again later.
Articles 1–20