| One-step generation of mice carrying mutations in multiple genes by CRISPR/Cas-mediated genome engineering H Wang, H Yang, CS Shivalila, MM Dawlaty, AW Cheng, F Zhang, ... cell 153 (4), 910-918, 2013 | 4329 | 2013 |
| One-step generation of mice carrying reporter and conditional alleles by CRISPR/Cas-mediated genome engineering H Yang, H Wang, CS Shivalila, AW Cheng, L Shi, R Jaenisch Cell 154 (6), 1370-1379, 2013 | 1930 | 2013 |
| Genetic engineering of human pluripotent cells using TALE nucleases D Hockemeyer, H Wang, S Kiani, CS Lai, Q Gao, JP Cassady, GJ Cost, ... Nature biotechnology 29 (8), 731-734, 2011 | 1545 | 2011 |
| Multiplexed activation of endogenous genes by CRISPR-on, an RNA-guided transcriptional activator system AW Cheng, H Wang, H Yang, L Shi, Y Katz, TW Theunissen, ... Cell research 23 (10), 1163-1171, 2013 | 951 | 2013 |
| Systematic identification of culture conditions for induction and maintenance of naive human pluripotency TW Theunissen, BE Powell, H Wang, M Mitalipova, DA Faddah, J Reddy, ... Cell stem cell 15 (4), 471-487, 2014 | 937 | 2014 |
| Generating genetically modified mice using CRISPR/Cas-mediated genome engineering H Yang, H Wang, R Jaenisch Nature protocols 9 (8), 1956-1968, 2014 | 587 | 2014 |
| Molecular criteria for defining the naive human pluripotent state TW Theunissen, M Friedli, Y He, E Planet, RC O’Neil, S Markoulaki, ... Cell stem cell 19 (4), 502-515, 2016 | 496 | 2016 |
| CRISPR-Cas9-mediated multiplex gene editing in CAR-T cells X Liu, Y Zhang, C Cheng, AW Cheng, X Zhang, N Li, C Xia, X Wei, X Liu, ... Cell research 27 (1), 154-157, 2017 | 353 | 2017 |
| Global transcriptional and translational repression in human-embryonic-stem-cell-derived Rett syndrome neurons Y Li, H Wang, J Muffat, AW Cheng, DA Orlando, J Lovén, S Kwok, ... Cell stem cell 13 (4), 446-458, 2013 | 343 | 2013 |
| Functional integration of dopaminergic neurons directly converted from mouse fibroblasts J Kim, SC Su, H Wang, AW Cheng, JP Cassady, MA Lodato, CJ Lengner, ... Cell stem cell 9 (5), 413-419, 2011 | 312 | 2011 |
| Impaired autophagy in the lipid-storage disorder Niemann-Pick type C1 disease S Sarkar, B Carroll, Y Buganim, D Maetzel, AHM Ng, JP Cassady, ... Cell reports 5 (5), 1302-1315, 2013 | 309 | 2013 |
| Efficient CRISPR/Cas9-mediated genome editing in mice by zygote electroporation of nuclease W Qin, SL Dion, PM Kutny, Y Zhang, AW Cheng, NL Jillette, A Malhotra, ... Genetics 200 (2), 423-430, 2015 | 278 | 2015 |
| Targeting hepatitis B virus cccDNA by CRISPR/Cas9 nuclease efficiently inhibits viral replication C Dong, L Qu, H Wang, L Wei, Y Dong, S Xiong Antiviral research 118, 110-117, 2015 | 269 | 2015 |
| Genetic and chemical correction of cholesterol accumulation and impaired autophagy in hepatic and neural cells derived from Niemann-Pick Type C patient-specific iPS cells D Maetzel, S Sarkar, H Wang, L Abi-Mosleh, P Xu, AW Cheng, Q Gao, ... Stem cell reports 2 (6), 866-880, 2014 | 240 | 2014 |
| TGF-β inhibition via CRISPR promotes the long-term efficacy of CAR T cells against solid tumors N Tang, C Cheng, X Zhang, M Qiao, N Li, W Mu, XF Wei, W Han, H Wang JCI insight 5 (4), 2020 | 236 | 2020 |
| CRISPR-Cas9 mediated LAG-3 disruption in CAR-T cells Y Zhang, X Zhang, C Cheng, W Mu, X Liu, N Li, X Wei, X Liu, C Xia, ... Frontiers of medicine 11, 554-562, 2017 | 199 | 2017 |
| Casilio: a versatile CRISPR-Cas9-Pumilio hybrid for gene regulation and genomic labeling AW Cheng, N Jillette, P Lee, D Plaskon, Y Fujiwara, W Wang, ... Cell research 26 (2), 254-257, 2016 | 162 | 2016 |
| TALEN-mediated editing of the mouse Y chromosome H Wang, YC Hu, S Markoulaki, GG Welstead, AW Cheng, CS Shivalila, ... Nature biotechnology 31 (6), 530-532, 2013 | 145 | 2013 |
| Single-cell analysis reveals that expression of nanog is biallelic and equally variable as that of other pluripotency factors in mouse ESCs DA Faddah, H Wang, AW Cheng, Y Katz, Y Buganim, R Jaenisch Cell stem cell 13 (1), 23-29, 2013 | 125 | 2013 |
| Phase I study of CAR-T cells with PD-1 and TCR disruption in mesothelin-positive solid tumors Z Wang, N Li, K Feng, M Chen, Y Zhang, Y Liu, Q Yang, J Nie, N Tang, ... Cellular & molecular immunology 18 (9), 2188-2198, 2021 | 116 | 2021 |
Albert W. Cheng, PhD 郑瑚博士Professor at Institute of Zoology, Chinese Academy of SciencesVerified email at cheng.bio
