Manuele Rebsamen
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Recognition of RNA virus by RIG-I results in activation of CARD9 and inflammasome signaling for interleukin 1β production
H Poeck, M Bscheider, O Gross, K Finger, S Roth, M Rebsamen, ...
Nature immunology 11 (1), 63-69, 2010
SLC38A9 is a component of the lysosomal amino acid sensing machinery that controls mTORC1
M Rebsamen, L Pochini, T Stasyk, MEG de Araújo, M Galluccio, ...
Nature 519 (7544), 477-481, 2015
TRADD protein is an essential component of the RIG-like helicase antiviral pathway
MC Michallet, E Meylan, MA Ermolaeva, J Vazquez, M Rebsamen, ...
Immunity 28 (5), 651-661, 2008
DAI/ZBP1 recruits RIP1 and RIP3 through RIP homotypic interaction motifs to activate NF‐κB
M Rebsamen, LX Heinz, E Meylan, MC Michallet, K Schroder, K Hofmann, ...
EMBO reports 10 (8), 916-922, 2009
Human haploid cell genetics reveals roles for lipid metabolism genes in nonapoptotic cell death
SJ Dixon, GE Winter, LS Musavi, ED Lee, B Snijder, M Rebsamen, ...
ACS chemical biology 10 (7), 1604-1609, 2015
NLRC5 deficiency selectively impairs MHC class I-dependent lymphocyte killing by cytotoxic T cells
F Staehli, K Ludigs, LX Heinz, Q Seguín-Estévez, I Ferrero, M Braun, ...
The Journal of Immunology 188 (8), 3820-3828, 2012
A cellular screen identifies ponatinib and pazopanib as inhibitors of necroptosis
GSF A Fauster, M Rebsamen, K V M Huber, J W Bigenzahn, A Stukalov, C-H ...
Cell Death and Disease, 2015
A reversible gene trap collection empowers haploid genetics in human cells
T Bürckstümmer, C Banning, P Hainzl, R Schobesberger, C Kerzendorfer, ...
Nature methods 10 (10), 965-971, 2013
The antiviral adaptor proteins Cardif and Trif are processed and inactivated by caspases
M Rebsamen, E Meylan, J Curran, J Tschopp
Cell Death & Differentiation 15 (11), 1804-1811, 2008
NLRX1/NOD5 deficiency does not affect MAVS signalling
M Rebsamen, J Vazquez, A Tardivel, G Guarda, J Curran, J Tschopp
Cell Death & Differentiation 18 (8), 1387-1387, 2011
LZTR1 is a regulator of RAS ubiquitination and signaling
JW Bigenzahn, GM Collu, F Kartnig, M Pieraks, GI Vladimer, LX Heinz, ...
Science 362 (6419), 1171-1177, 2018
The lipid-modifying enzyme SMPDL3B negatively regulates innate immunity
LX Heinz, CL Baumann, MS Köberlin, B Snijder, R Gawish, G Shui, ...
Cell reports 11 (12), 1919-1928, 2015
LAMTOR/Ragulator is a negative regulator of Arl8b- and BORC-dependent late endosomal positioning
HLA Filipek PA, de Araujo MEG, Vogel GF, De Smet CH, Eberharter D, Rebsamen ...
J Cell Biol, 2017
The bicarbonate transporter SLC4A7 plays a key role in macrophage phagosome acidification
V Sedlyarov, R Eichner, E Girardi, P Essletzbichler, U Goldmann, ...
Cell host & microbe 23 (6), 766-774. e5, 2018
An inducible retroviral expression system for tandem affinity purification mass-spectrometry-based proteomics identifies mixed lineage kinase domain-like protein (MLKL) as an …
JW Bigenzahn, A Fauster, M Rebsamen, RK Kandasamy, S Scorzoni, ...
Molecular & Cellular Proteomics 15 (3), 1139-1150, 2016
The death domain-containing protein Unc5CL is a novel MyD88-independent activator of the pro-inflammatory IRAK signaling cascade
LX Heinz, M Rebsamen, DC Rossi, F Staehli, K Schroder, M Quadroni, ...
Cell Death & Differentiation 19 (4), 722-731, 2012
TASL is the SLC15A4-associated adaptor for IRF5 activation by TLR7–9
LX Heinz, JE Lee, U Kapoor, F Kartnig, V Sedlyarov, K Papakostas, ...
Nature 581 (7808), 316-322, 2020
Protein interaction networks in innate immunity
M Rebsamen, RK Kandasamy, G Superti-Furga
Trends in immunology 34 (12), 610-619, 2013
A time-resolved molecular map of the macrophage response to VSV infection
Kandasamy RK, Vladimir GI, Snijder B, Müller AC, Rebsamen M, Bigenzahn JW ...
npj Systems Biology and Applications, 2016
SLC38A9: A lysosomal amino acid transporter at the core of the amino acid-sensing machinery that controls MTORC1
M Rebsamen, G Superti-Furga
Autophagy 12 (6), 1061-1062, 2016
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