| Lysine-specific molecular tweezers are broad-spectrum inhibitors of assembly and toxicity of amyloid proteins S Sinha, DHJ Lopes, Z Du, ES Pang, A Shanmugam, A Lomakin, ... Journal of the American Chemical Society 133 (42), 16958-16969, 2011 | 336 | 2011 |
| Mechanism of islet amyloid polypeptide fibrillation at lipid interfaces studied by infrared reflection absorption spectroscopy DHJ Lopes, A Meister, A Gohlke, A Hauser, A Blume, R Winter Biophysical journal 93 (9), 3132-3141, 2007 | 208 | 2007 |
| Contribuições da perspectiva institucional para a análise das organizações: possibilidades teóricas, empíricas e de aplicação CA Carvalho, MMF Vieira, D LOPES Organizações, cultura e desenvolvimento local: a agenda de pesquisa do …, 2003 | 136 | 2003 |
| A key role for lysine residues in amyloid β-protein folding, assembly, and toxicity S Sinha, DHJ Lopes, G Bitan ACS Chemical Neuroscience 3 (6), 473-481, 2012 | 135 | 2012 |
| Towards an understanding of the temperature/pressure configurational and free-energy landscape of biomolecules R Winter, D Lopes, S Grudzielanek, K Vogtt Walter de Gruyter 32 (1), 41-97, 2007 | 112 | 2007 |
| Angiotensin-converting enzyme overexpression in myelomonocytes prevents Alzheimer’s-like cognitive decline KE Bernstein, Y Koronyo, BC Salumbides, J Sheyn, L Pelissier, ... The Journal of clinical investigation 124 (3), 1000-1012, 2014 | 107 | 2014 |
| Induction of methionine-sulfoxide reductases protects neurons from amyloid β-protein insults in vitro and in vivo J Moskovitz, P Maiti, DHJ Lopes, DB Oien, A Attar, T Liu, S Mittal, J Hayes, ... Biochemistry 50 (49), 10687-10697, 2011 | 66 | 2011 |
| Design of β-amyloid aggregation inhibitors from a predicted structural motif PA Novick, DH Lopes, KM Branson, A Esteras-Chopo, IA Graef, G Bitan, ... Journal of Medicinal Chemistry 55 (7), 3002-3010, 2012 | 64 | 2012 |
| Peripherally derived angiotensin converting enzyme-enhanced macrophages alleviate Alzheimer-related disease M Koronyo-Hamaoui, J Sheyn, EY Hayden, S Li, DT Fuchs, GC Regis, ... Brain 143 (1), 336-358, 2020 | 62 | 2020 |
| Molecular tweezers inhibit islet amyloid polypeptide assembly and toxicity by a new mechanism DHJ Lopes, A Attar, G Nair, EY Hayden, Z Du, K McDaniel, S Dutt, ... ACS chemical biology 10 (6), 1555-1569, 2015 | 51 | 2015 |
| Amyloidogenicity and cytotoxicity of recombinant mature human islet amyloid polypeptide (rhIAPP) DHJ Lopes, C Colin, TL Degaki, ACV de Sousa, MNN Vieira, A Sebollela, ... Journal of Biological Chemistry 279 (41), 42803-42810, 2004 | 50 | 2004 |
| C-terminal tetrapeptides inhibit Aβ42-induced neurotoxicity primarily through specific interaction at the N-terminus of Aβ42 H Li, Z Du, DHJ Lopes, EA Fradinger, C Wang, G Bitan Journal of medicinal chemistry 54 (24), 8451-8460, 2011 | 39 | 2011 |
| Urea increases tolerance of yeast inorganic pyrophosphatase activity to ethanol: the other side of urea interaction with proteins DHJ Lopes, M Sola-Penna Archives of Biochemistry and Biophysics 394 (1), 61-66, 2001 | 36 | 2001 |
| Effects of trehalose and ethanol on yeast cytosolic pyrophosphatase DHJ Lopes, JR Meyer-Fernandes, M Sola-Penna Zeitschrift für Naturforschung C 54 (3-4), 186-190, 1999 | 20 | 1999 |
| Tranilast binds to Aβ monomers and promotes Aβ fibrillation CR Connors, DJ Rosenman, DHJ Lopes, S Mittal, G Bitan, M Sorci, ... Biochemistry 52 (23), 3995-4002, 2013 | 17 | 2013 |
| Redesigning the folding energetics of a model three-helix bundle protein by site-directed mutagenesis DHJ Lopes, A Chapeaurouge, GA Manderson, JS Johansson, ST Ferreira Journal of Biological Chemistry 279 (12), 10991-10996, 2004 | 17 | 2004 |
| Application of photochemical cross-linking to the study of oligomerization of amyloidogenic proteins DHJ Lopes, S Sinha, C Rosensweig, G Bitan Amyloid Proteins: Methods and Protocols, 11-21, 2012 | 16 | 2012 |
| A Two‐Step Strategy for Structure–Activity Relationship Studies of N‐Methylated Aβ42 C‐Terminal Fragments as Aβ42 Toxicity Inhibitors H Li, R Zemel, DHJ Lopes, BH Monien, G Bitan ChemMedChem 7 (3), 515-522, 2012 | 13 | 2012 |
| Islet amyloid polypeptide and high hydrostatic pressure: towards an understanding of the fibrillization process DHJ Lopes, V Smirnovas, R Winter Journal of Physics: Conference Series 121 (11), 112002, 2008 | 3 | 2008 |
| Mechanism of IAPP fibrillation at lipid interfaces studied by infrared reflection absorption spectroscopy DHJ Lopes, A Meister, A Gohlke, A Hauser, A Blume, R Winter Biophys J. doi 10, 2007 | 3 | 2007 |
