A versatile platform for generating engineered extracellular vesicles with defined therapeutic properties K Dooley, RE McConnell, K Xu, ND Lewis, S Haupt, MR Youniss, S Martin, ... Molecular Therapy 29 (5), 1729-1743, 2021 | 170 | 2021 |
Replacing antibodies: engineering new binding proteins S Banta, K Dooley, O Shur Annual review of biomedical engineering 15, 93-113, 2013 | 130 | 2013 |
Exosome-mediated genetic reprogramming of tumor-associated macrophages by exoASO-STAT6 leads to potent monotherapy antitumor activity S Kamerkar, C Leng, O Burenkova, SC Jang, C McCoy, K Zhang, ... Science advances 8 (7), eabj7002, 2022 | 112 | 2022 |
Co-delivery of a growth factor and a tissue-protective molecule using elastin biopolymers accelerates wound healing in diabetic mice J Devalliere, K Dooley, Y Hu, SS Kelangi, BE Uygun, ML Yarmush Biomaterials 141, 149-160, 2017 | 88 | 2017 |
ExoSTING, an extracellular vesicle loaded with STING agonists, promotes tumor immune surveillance SC Jang, KD Economides, RJ Moniz, CL Sia, N Lewis, C McCoy, T Zi, ... Communications biology 4 (1), 497, 2021 | 87 | 2021 |
Rapid Development of New Protein Biosensors Utilizing Peptides Obtained via Phage Display J Wu, JP Park, K Dooley, DM Cropek, AC West, S Banta PloS one 6 (10), e24948, 2011 | 68 | 2011 |
A dual enzyme electrochemical assay for the detection of organophosphorus compounds using organophosphorus hydrolase and horseradish peroxidase A Sahin, K Dooley, DM Cropek, AC West, S Banta Sensors and Actuators B: Chemical, 2011 | 67 | 2011 |
Improving functional re-endothelialization of acellular liver scaffold using REDV cell-binding domain J Devalliere, Y Chen, K Dooley, ML Yarmush, BE Uygun Acta biomaterialia 78, 151-164, 2018 | 64 | 2018 |
Exosome surface display of IL12 results in tumor-retained pharmacology with superior potency and limited systemic exposure compared with recombinant IL12 ND Lewis, CL Sia, K Kirwin, S Haupt, G Mahimkar, T Zi, K Xu, K Dooley, ... Molecular cancer therapeutics 20 (3), 523-534, 2021 | 56 | 2021 |
Engineering of an Environmentally Responsive Beta Roll Peptide for Use As a Calcium-Dependent Cross-Linking Domain for Peptide Hydrogel Formation K Dooley, YH Kim, HD Lu, R Tu, S Banta Biomacromolecules 13 (6), 1758-1764, 2012 | 55 | 2012 |
A designed, phase changing RTX-based peptide for efficient bioseparations O Shur, K Dooley, M Blenner, M Baltimore, S Banta BioTechniques 54 (4), 197-206, 2013 | 30 | 2013 |
Improving the performance of methanol biofuel cells utilizing an enzyme cascade bioanode with DNA-bridged substrate channeling L Xia, K Van Nguyen, Y Holade, H Han, K Dooley, P Atanassov, S Banta, ... ACS Energy Letters 2 (6), 1435-1438, 2017 | 29 | 2017 |
Doubling the cross-linking interface of a rationally designed beta roll peptide for calcium-dependent proteinaceous hydrogel formation K Dooley, B Bulutoglu, S Banta Biomacromolecules 15 (10), 3617-3624, 2014 | 25 | 2014 |
In vivo tracking of [89Zr] Zr-labeled engineered extracellular vesicles by PET reveals organ-specific biodistribution based upon the route of administration S Patel, KF Schmidt, M Farhoud, T Zi, SC Jang, K Dooley, D Kentala, ... Nuclear medicine and biology 112, 20-30, 2022 | 16 | 2022 |
exoSTING: An engineered exosome therapeutic that selectively delivers STING agonist to the tumor resident antigen-presenting cells resulting in improved tumor antigen-specific … SC Jang, RJ Moniz, CL Sia, RA Harrison, D Houde, N Ross, K Xu, ... Cancer Research 79 (13_Supplement), 944-944, 2019 | 13 | 2019 |
Catch and release: engineered Allosterically regulated β-roll peptides enable on/off biomolecular recognition B Bulutoglu, K Dooley, G Szilvay, M Blenner, S Banta ACS Synthetic Biology 6 (9), 1732-1741, 2017 | 12 | 2017 |
Preparation of therapeutic exosomes using membrane proteins KP Dooley, RA Harrison, RE McConnell, K Xu, DJ Houde, N Ross, ... US Patent 10,561,740, 2020 | 11 | 2020 |
Functionalized biopolymer particles enhance performance of a tissue-protective peptide under proteolytic and thermal stress K Dooley, J Devalliere, BE Uygun, ML Yarmush Biomacromolecules 17 (6), 2073-2079, 2016 | 6 | 2016 |
Compositions of Engineered Exosomes and Methods of Loading Luminal Exosome Payloads RE McConnell, KP Dooley, RA Harrison, K Xu, DJ Houde, S Haupt, ... US Patent App. 16/194,230, 2019 | 3 | 2019 |
Preparation of therapeutic exosomes using membrane proteins KP Dooley, RA Harrison, RE McConnell, K Xu, DJ Houde, N Ross, ... US Patent 11,679,164, 2023 | 2 | 2023 |