Isidro Hotzel
Isidro Hotzel
Unknown affiliation
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Membrane-proximal epitope facilitates efficient T cell synapse formation by anti-FcRH5/CD3 and is a requirement for myeloma cell killing
J Li, NJ Stagg, J Johnston, MJ Harris, SA Menzies, D DiCara, V Clark, ...
Cancer cell 31 (3), 383-395, 2017
A strategy for risk mitigation of antibodies with fast clearance
I Hötzel, FP Theil, LJ Bernstein, S Prabhu, R Deng, L Quintana, J Lutman, ...
MAbs 4 (6), 753-760, 2012
The artiodactyl APOBEC3 innate immune repertoire shows evidence for a multi-functional domain organization that existed in the ancestor of placental mammals
RS LaRue, SR Jónsson, KAT Silverstein, M Lajoie, D Bertrand, ...
BMC molecular biology 9, 1-20, 2008
Molecular basis for negative regulation of the glucagon receptor
CM Koth, JM Murray, S Mukund, A Madjidi, A Minn, HJ Clarke, T Wong, ...
Proceedings of the National Academy of Sciences 109 (36), 14393-14398, 2012
Massively parallel single-cell B-cell receptor sequencing enables rapid discovery of diverse antigen-reactive antibodies
LD Goldstein, YJJ Chen, J Wu, S Chaudhuri, YC Hsiao, K Schneider, ...
Communications biology 2 (1), 304, 2019
Antibody-mediated targeting of tau in vivo does not require effector function and microglial engagement
SH Lee, CE Le Pichon, O Adolfsson, V Gafner, M Pihlgren, H Lin, ...
Cell reports 16 (6), 1690-1700, 2016
Structure, sequence, and transcriptional analysis of the Babesia bovis rap-1 multigene locus
CE Suarez, GH Palmer, I Hötzel, TF McElwain
Molecular and biochemical parasitology 93 (2), 215-224, 1998
Evaluating the use of antibody variable region (Fv) charge as a risk assessment tool for predicting typical cynomolgus monkey pharmacokinetics
DB Yadav, VK Sharma, CA Boswell, I Hotzel, D Tesar, Y Shang, Y Ying, ...
Journal of Biological Chemistry 290 (50), 29732-29741, 2015
Organization, transcription, and expression of rhoptry associated protein genes in the Babesia bigemina rap-1 locus
CE Suarez, GH Palmer, M Florin-Christensen, SA Hines, I Hötzel, ...
Molecular and biochemical parasitology 127 (2), 101-112, 2003
Antibody semorinemab reduces tau pathology in a transgenic mouse model and engages tau in patients with Alzheimer’s disease
G Ayalon, SH Lee, O Adolfsson, C Foo-Atkins, JK Atwal, M Blendstrup, ...
Science Translational Medicine 13 (593), eabb2639, 2021
Genetic variation in the dimorphic regions of RAP-1 genes and rap-1 loci of Babesia bigemina
I Hötzel, CE Suarez, TF McElwain, GH Palmer
Molecular and biochemical parasitology 90 (2), 479-489, 1997
Protein design with guided discrete diffusion
N Gruver, S Stanton, N Frey, TGJ Rudner, I Hotzel, J Lafrance-Vanasse, ...
Advances in neural information processing systems 36, 2024
The INNs and outs of antibody nonproprietary names
TD Jones, PJ Carter, A Plückthun, M Vásquez, RGE Holgate, I Hötzel, ...
MAbs 8 (1), 1-9, 2016
Efficient production of antibodies against a mammalian integral membrane protein by phage display
I Hötzel, V Chiang, J Diao, H Pantua, HR Maun, SB Kapadia
Protein Engineering, Design & Selection 24 (9), 679-689, 2011
Differentiation of classical swine fever virus from ruminant pestiviruses by reverse transcription and polymerase chain reaction (RT-PCR)
CW Canal, I Hotzel, LL de Almeida, PM Roehe, A Masuda
Veterinary Microbiology 48 (3-4), 373-379, 1996
Humanized and affinity matured antibodies to FcRH5 and methods of use
I Hotzel, TT Junttila, J Li, J Scheer, D Dicara, D Ellerman, C Spiess, ...
US Patent 10,323,094, 2019
Host range of small-ruminant lentivirus cytopathic variants determined with a selectable caprine arthritis-encephalitis virus pseudotype system
I Hötzel, WP Cheevers
Journal of virology 75 (16), 7384-7391, 2001
Structural investigation of human S. aureus-targeting antibodies that bind wall teichoic acid
R Fong, K Kajihara, M Chen, I Hotzel, S Mariathasan, WLW Hazenbos, ...
MAbs 10 (7), 979-991, 2018
Inhibitory mechanism of an allosteric antibody targeting the glucagon receptor
S Mukund, Y Shang, HJ Clarke, A Madjidi, JE Corn, L Kates, G Kolumam, ...
Journal of Biological Chemistry 288 (50), 36168-36178, 2013
Differential receptor usage of small ruminant lentiviruses in ovine and caprine cells: host range but not cytopathic phenotype is determined by receptor usage
I Hötzel, WP Cheevers
Virology 301 (1), 21-31, 2002
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