Design of a hydrogen peroxide-activatable agent that specifically targets cancer cells AK Vadukoot, SF AbdulSalam, M Wunderlich, ED Pullen, ... Bioorganic & medicinal chemistry 22 (24), 6885-6892, 2014 | 28 | 2014 |
Novel ROS-activated agents utilize a tethered amine to selectively target acute myeloid leukemia TR Bell-Horwath, AK Vadukoot, FS Thowfeik, G Li, M Wunderlich, ... Bioorganic & medicinal chemistry letters 23 (10), 2951-2954, 2013 | 22 | 2013 |
Discovery and Characterization of 1H-Pyrazol-5-yl-2-phenylacetamides as Novel, Non-Urea-Containing GIRK1/2 Potassium Channel Activators JM Wieting, AK Vadukoot, S Sharma, KK Abney, TM Bridges, JS Daniels, ... ACS chemical neuroscience 8 (9), 1873-1879, 2017 | 20 | 2017 |
Curcumin as a Potential Therapeutic Agent in Certain Cancer Types AK Vadukoot, M Shabna, V Pratikkumar H Cureus 14 (3), e22825, 2022 | 15 | 2022 |
Synthesis and SAR Studies of 1H-Pyrrolo[2,3-b]pyridine-2-carboxamides as Phosphodiesterase 4B (PDE4B) Inhibitors AK Vadukoot, S Sharma, CD Aretz, S Kumar, N Gautam, Y Alnouti, ... ACS Medicinal Chemistry Letters 11 (10), 1848-1854, 2020 | 15 | 2020 |
KVA-D-88, a Novel Preferable Phosphodiesterase 4B Inhibitor, Decreases Cocaine-Mediated Reward Properties in Vivo ME Burkovetskaya, Q Liu, AK Vadukoot, N Gautam, Y Alnouti, S Kumar, ... ACS chemical neuroscience 11 (15), 2231-2242, 2020 | 9 | 2020 |
Discovery of Small Molecule Renal Outer Medullary Potassium (ROMK) Channel Inhibitors: A Brief History of Medicinal Chemistry Approaches To Develop Novel Diuretic Therapeutics … CD Aretz, AK Vadukoot, CR Hopkins Journal of Medicinal Chemistry 62 (19), 8682-8694, 2019 | 7 | 2019 |
Functional characterization of Pneumocystis carinii inositol transporter 1 MT Cushion, MS Collins, T Sesterhenn, A Porollo, AK Vadukoot, ... MBio 7 (6), 10.1128/mbio. 01851-16, 2016 | 7 | 2016 |
Discovery, synthesis and characterization of a series of 7-aryl-imidazo[1,2-a]pyridine-3-ylquinolines as activin-like kinase (ALK) inhibitors CRH Darren W. Engers, Sean R. Bollinger, Andrew Felts, Anish K. Vadukoot ... Bioorganic & Medicinal Chemistry Letters, 2020 | 6 | 2020 |
Discovery and characterization of benzyloxy piperidine based dopamine 4 receptor antagonists KT Tolentino, V Mashinson, AK Vadukoot, CR Hopkins Bioorganic & medicinal chemistry letters 61, 128615, 2022 | 4 | 2022 |
Discovery, synthesis and biological evaluation of a series of N-(phenylcarbamothioyl)-2-napthamides as inhibitors of Claudin-1 V Mashinson, TM Webster, AK Vadukoot, KT Tolentino, P Simeon, ... Bioorganic & Medicinal Chemistry 92, 117416, 2023 | 1 | 2023 |
PROTACs: Opportunities and challenges ahead in the field of drug discovery AK Vadukoot International Journal of Medicine and Public Health 12 (3), 96-96, 2022 | 1 | 2022 |
Synthesis and biological characterization of a series of 2-sulfonamidebenzamides as allosteric modulators of mrgX1 S Sharma, Q Peng, AK Vadukoot, CD Aretz, AA Jensen, AI Wallick, ... ACS Medicinal Chemistry Letters 13 (5), 841-847, 2022 | 1 | 2022 |
DEVELOPMENT OF NOVEL CLOFARABINE ANALOGS FOR CANCER THERAPY Omar Moukha-Chafiq, Corinne Elizabeth Augelli-Szafran, Rebecca Boohaker ... WO Patent WO 2023/076392 A1, 2023 | | 2023 |
Discovery, synthesis and biological evaluation of a series of N-(phenylcarbamothioyl)-2-napthamides as inhibitors of Claudin-1 C Hopkins, V Mashinson, T Webster, A Vadukoot, K Tolentino, P Simeon, ... | | 2023 |
Further synthesis and biological characterization of a series of 2-sulfonamidebenzamides as allosteric modulators of MrgX1 S Sharma, Q Peng, A Vadukoot, C Aretz, A Jensen, A Wallick, X Dong, ... | | 2021 |
Inhibition of BMP signaling, compounds, compositions and uses thereof CR Hopkins, M Ritter, CC Hong, A Vadukoot, DW Engers, CW Lindsley US Patent 10,745,400, 2020 | | 2020 |
Hydrogen peroxide-activated compounds as selective anti-cancer therapeutics EJ Merino, J Mulloy, AK Vadukoot, M Wunderlich, SF Abdulsalam US Patent 10,071,954, 2018 | | 2018 |
Synthesis, structure activity relationship studies and biological evaluation of novel and selective 1H-pyrrolo [2, 3-b] pyridine-2-carboxamides as related phosphodiesterase 4B … AK Vadukoot, S Sharma, CR Hopkins ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 255, 2018 | | 2018 |
Discovery and characterization of 1H-pyrazol-5-yl-2-phenylacetamides as novel, non-urea containing GIRK1/2 potassium channel activators S Sharma, J Wieting, A Vadukoot, K Abney, T Bridges, B Vo, A Andersone, ... ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 254, 2017 | | 2017 |