Hang Hubert Yin
Hang Hubert Yin
Professor & Deputy Dean, School of Pharmaceutical Sciences, Tsinghua University
Verified email at tsinghua.edu.cn - Homepage
Title
Cited by
Cited by
Year
Minimal information for studies of extracellular vesicles 2018 (MISEV2018): a position statement of the International Society for Extracellular Vesicles and update of the …
C Théry, KW Witwer, E Aikawa, MJ Alcaraz, JD Anderson, ...
Journal of extracellular vesicles 7 (1), 1535750, 2018
27042018
Strategies for targeting protein–protein interactions with synthetic agents
H Yin, AD Hamilton
Angewandte Chemie International Edition 44 (27), 4130-4163, 2005
5402005
Evidence that opioids may have toll-like receptor 4 and MD-2 effects
MR Hutchinson, Y Zhang, M Shridhar, JH Evans, MM Buchanan, TX Zhao, ...
Brain, behavior, and immunity 24 (1), 83-95, 2010
4592010
Morphine activates neuroinflammation in a manner parallel to endotoxin
X Wang, LC Loram, K Ramos, AJ de Jesus, J Thomas, K Cheng, A Reddy, ...
Proceedings of the national academy of sciences 109 (16), 6325-6330, 2012
3512012
Design and application of an α‐helix‐mimetic scaffold based on an oligoamide‐foldamer strategy: antagonism of the Bak BH3/Bcl‐xL complex
JT Ernst, J Becerril, HS Park, H Yin, AD Hamilton
Angewandte Chemie International Edition 42 (5), 535-539, 2003
3352003
Development of a Potent Bcl-xL Antagonist Based on α-Helix Mimicry
O Kutzki, HS Park, JT Ernst, BP Orner, H Yin, AD Hamilton
Journal of the American Chemical Society 124 (40), 11838-11839, 2002
3292002
Toll‐like receptor 4 in CNS pathologies
MM Buchanan, M Hutchinson, LR Watkins, H Yin
Journal of neurochemistry 114 (1), 13-27, 2010
3232010
Computational design of peptides that target transmembrane helices
H Yin, JS Slusky, BW Berger, RS Walters, G Vilaire, RI Litvinov, JD Lear, ...
Science 315 (5820), 1817-1822, 2007
3032007
Terphenyl‐based helical mimetics that disrupt the p53/HDM2 interaction
H Yin, G Lee, HS Park, GA Payne, JM Rodriguez, SM Sebti, AD Hamilton
Angewandte Chemie 117 (18), 2764-2767, 2005
2992005
Inhibition of JAK-STAT signaling stimulates adult satellite cell function
FD Price, J Von Maltzahn, CF Bentzinger, NA Dumont, H Yin, NC Chang, ...
Nature medicine 20 (10), 1174-1181, 2014
2712014
Terphenyl-Based Bak BH3 α-Helical Proteomimetics as Low-Molecular-Weight Antagonists of Bcl-xL
H Yin, G Lee, KA Sedey, O Kutzki, HS Park, BP Orner, JT Ernst, HG Wang, ...
Journal of the American Chemical Society 127 (29), 10191-10196, 2005
2552005
Opioid activation of toll-like receptor 4 contributes to drug reinforcement
MR Hutchinson, AL Northcutt, T Hiranita, X Wang, SS Lewis, J Thomas, ...
Journal of Neuroscience 32 (33), 11187-11200, 2012
2262012
Morphine paradoxically prolongs neuropathic pain in rats by amplifying spinal NLRP3 inflammasome activation
PM Grace, KA Strand, EL Galer, DJ Urban, X Wang, MV Baratta, ...
Proceedings of the National Academy of Sciences 113 (24), E3441-E3450, 2016
2172016
Terephthalamide derivatives as mimetics of helical peptides: disruption of the Bcl-xL/Bak interaction
H Yin, G Lee, KA Sedey, JM Rodriguez, HG Wang, SM Sebti, AD Hamilton
Journal of the American Chemical Society 127 (15), 5463-5468, 2005
1752005
Concise review: Developing best‐practice models for the therapeutic use of extracellular vesicles
AT Reiner, KW Witwer, BWM Van Balkom, J De Beer, C Brodie, ...
Stem cells translational medicine 6 (8), 1730-1739, 2017
1642017
Drugging membrane protein interactions
H Yin, AD Flynn
Annual review of biomedical engineering 18, 51-76, 2016
1582016
Activation of MyD88-dependent TLR1/2 signaling by misfolded α-synuclein, a protein linked to neurodegenerative disorders
SG Daniele, D Béraud, C Davenport, K Cheng, H Yin, KA Maguire-Zeiss
Science signaling 8 (376), ra45-ra45, 2015
1522015
Exosomes and microvesicles: identification and targeting by particle size and lipid chemical probes
N Kastelowitz, H Yin
Chembiochem: a European journal of chemical biology 15 (7), 923, 2014
1432014
DAT isn’t all that: cocaine reward and reinforcement require Toll-like receptor 4 signaling
AL Northcutt, MR Hutchinson, X Wang, MV Baratta, T Hiranita, ...
Molecular psychiatry 20 (12), 1525-1537, 2015
1392015
The BH3 α-helical mimic BH3-M6 disrupts Bcl-XL, Bcl-2, and MCL-1 protein-protein interactions with Bax, Bak, Bad, or Bim and induces apoptosis in a Bax-and Bim-dependent manner
A Kazi, J Sun, K Doi, SS Sung, Y Takahashi, H Yin, JM Rodriguez, ...
Journal of Biological Chemistry 286 (11), 9382-9392, 2011
1392011
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