Paolo Armando Gagliardi
Paolo Armando Gagliardi
Institute of Cell Biology, University of Bern, Switzerland
Verified email at - Homepage
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PDK1: At the crossroad of cancer signaling pathways
PA Gagliardi, A Puliafito, L Primo
Seminars in cancer biology 48, 27-35, 2018
Endothelial podosome rosettes regulate vascular branching in tumour angiogenesis
G Seano, G Chiaverina, PA Gagliardi, L Di Blasio, A Puliafito, C Bouvard, ...
Nature cell biology 16 (10), 931-941, 2014
The miR-126 regulates angiopoietin-1 signaling and vessel maturation by targeting p85β
R Sessa, G Seano, L Di Blasio, PA Gagliardi, C Isella, E Medico, F Cotelli, ...
Biochimica et Biophysica Acta (BBA)-Molecular Cell Research 1823 (10), 1925-1935, 2012
PDK1: A signaling hub for cell migration and tumor invasion
PA Gagliardi, L Di Blasio, L Primo
Biochimica et Biophysica Acta (BBA)-Reviews on Cancer 1856 (2), 178-188, 2015
Modeling human tumor angiogenesis in a three-dimensional culture system
G Seano, G Chiaverina, PA Gagliardi, L Di Blasio, R Sessa, F Bussolino, ...
Blood, The Journal of the American Society of Hematology 121 (21), e129-e137, 2013
3-phosphoinositide-dependent kinase 1 controls breast tumor growth in a kinase-dependent but Akt-independent manner
PA Gagliardi, L Di Blasio, F Orso, G Seano, R Sessa, D Taverna, ...
Neoplasia 14 (8), 719-IN19, 2012
Increased Expression of α6 Integrin in Endothelial Cells Unveils a Proangiogenic Role for Basement MembraneProangiogenic Role for α6 Integrin
L Primo, G Seano, C Roca, F Maione, PA Gagliardi, R Sessa, M Martinelli, ...
Cancer research 70 (14), 5759-5769, 2010
PI3K/mTOR inhibition promotes the regression of experimental vascular malformations driven by PIK3CA-activating mutations
L Di Blasio, A Puliafito, PA Gagliardi, V Comunanza, D Somale, ...
Cell death & disease 9 (2), 1-15, 2018
Collective ERK/Akt activity waves orchestrate epithelial homeostasis by driving apoptosis-induced survival
PA Gagliardi, M Dobrzyński, MA Jacques, C Dessauges, P Ender, Y Blum, ...
Developmental cell 56 (12), 1712-1726. e6, 2021
Serine/threonine kinase 3-phosphoinositide-dependent protein kinase-1 (PDK1) as a key regulator of cell migration and cancer dissemination
L Di Blasio, PA Gagliardi, A Puliafito, L Primo
Cancers 9 (3), 25, 2017
PDK1-mediated activation of MRCKα regulates directional cell migration and lamellipodia retraction
PA Gagliardi, L Di Blasio, A Puliafito, G Seano, R Sessa, F Chianale, ...
Journal of Cell Biology 206 (3), 415-434, 2014
Three-dimensional chemotaxis-driven aggregation of tumor cells
A Puliafito, A De Simone, G Seano, PA Gagliardi, L Di Blasio, F Chianale, ...
Scientific reports 5 (1), 1-12, 2015
Real-time monitoring of cell protrusion dynamics by impedance responses
PA Gagliardi, A Puliafito, L Di Blasio, F Chianale, D Somale, G Seano, ...
Scientific reports 5 (1), 1-12, 2015
MRCKα is activated by caspase cleavage to assemble an apical actin ring for epithelial cell extrusion
PA Gagliardi, D Somale, A Puliafito, G Chiaverina, L di Blasio, M Oneto, ...
Journal of Cell Biology 217 (1), 231-249, 2018
Colorectal cancer residual disease at maximal response to EGFR blockade displays a druggable Paneth cell–like phenotype
B Lupo, F Sassi, M Pinnelli, F Galimi, ER Zanella, V Vurchio, G Migliardi, ...
Science translational medicine 12 (555), eaax8313, 2020
PDK1 regulates focal adhesion disassembly by modulating endocytosis of αvβ3 integrin
L Di Blasio, PA Gagliardi, A Puliafito, R Sessa, G Seano, F Bussolino, ...
Journal of cell science 128 (5), 863-877, 2015
Peritoneal and hematogenous metastases of ovarian cancer cells are both controlled by the p90RSK through a self-reinforcing cell autonomous mechanism
E Torchiaro, A Lorenzato, M Olivero, D Valdembri, PA Gagliardi, M Gai, ...
Oncotarget 7 (1), 712, 2016
Death for life: a path from apoptotic signaling to tissue-scale effects of apoptotic epithelial extrusion
PA Gagliardi, L Primo
Cellular and Molecular Life Sciences 76 (18), 3571-3581, 2019
CODEX, a neural network approach to explore signaling dynamics landscapes
MA Jacques, M Dobrzyński, PA Gagliardi, R Sznitman, O Pertz
Molecular systems biology 17 (4), e10026, 2021
Optogenetic actuator/ERK biosensor circuits identify MAPK network nodes that shape ERK dynamics
C Dessauges, J Mikelson, M Dobrzyński, MA Jacques, A Frismantiene, ...
BioRxiv, 2021.07. 27.453955, 2022
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