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A subtype of childhood acute lymphoblastic leukaemia with poor treatment outcome: a genome-wide classification study
ML Den Boer, M van Slegtenhorst, RX De Menezes, MH Cheok, ...
The lancet oncology 10 (2), 125-134, 2009
10952009
A 17-gene stemness score for rapid determination of risk in acute leukaemia
SWK Ng, A Mitchell, JA Kennedy, WC Chen, J McLeod, N Ibrahimova, ...
Nature 540 (7633), 433-437, 2016
7652016
Gene-expression patterns in drug-resistant acute lymphoblastic leukemia cells and response to treatment
A Holleman, MH Cheok, ML den Boer, W Yang, AJP Veerman, ...
New England Journal of Medicine 351 (6), 533-542, 2004
7262004
TET2 mutation is an independent favorable prognostic factor in myelodysplastic syndromes (MDSs)
O Kosmider, V Gelsi-Boyer, M Cheok, S Grabar, V Della-Valle, F Picard, ...
Blood, The Journal of the American Society of Hematology 114 (15), 3285-3291, 2009
3552009
Acute lymphoblastic leukaemia: a model for the pharmacogenomics of cancer therapy
MH Cheok, WE Evans
Nature Reviews Cancer 6 (2), 117-129, 2006
2992006
Treatment-specific changes in gene expression discriminate in vivo drug response in human leukemia cells
MH Cheok, W Yang, CH Pui, JR Downing, C Cheng, CW Naeve, ...
Nature genetics 34 (1), 85-90, 2003
2952003
Genetic polymorphism of inosine triphosphate pyrophosphatase is a determinant of mercaptopurine metabolism and toxicity during treatment for acute lymphoblastic leukemia
G Stocco, MH Cheok, KR Crews, T Dervieux, D French, D Pei, W Yang, ...
Clinical Pharmacology & Therapeutics 85 (2), 164-172, 2009
2672009
The expression of 70 apoptosis genes in relation to lineage, genetic subtype, cellular drug resistance, and outcome in childhood acute lymphoblastic leukemia
A Holleman, ML den Boer, RX de Menezes, MH Cheok, C Cheng, ...
Blood 107 (2), 769-776, 2006
1982006
Identification of genes associated with chemotherapy crossresistance and treatment response in childhood acute lymphoblastic leukemia
S Lugthart, MH Cheok, ML den Boer, W Yang, A Holleman, C Cheng, ...
Cancer cell 7 (4), 375-386, 2005
1942005
Folate pathway gene expression differs in subtypes of acute lymphoblastic leukemia and influences methotrexate pharmacodynamics
L Kager, M Cheok, W Yang, G Zaza, Q Cheng, JC Panetta, CH Pui, ...
The Journal of clinical investigation 115 (1), 110-117, 2005
1872005
Incidence and prognostic value of TET2 alterations in de novo acute myeloid leukemia achieving complete remission
O Nibourel, O Kosmider, M Cheok, N Boissel, A Renneville, N Philippe, ...
Blood, The Journal of the American Society of Hematology 116 (7), 1132-1135, 2010
1722010
Transporter-mediated protection against thiopurine-induced hematopoietic toxicity
P Krishnamurthy, M Schwab, K Takenaka, D Nachagari, J Morgan, ...
Cancer research 68 (13), 4983-4989, 2008
1612008
Somatic deletions of genes regulating MSH2 protein stability cause DNA mismatch repair deficiency and drug resistance in human leukemia cells
B Diouf, Q Cheng, NF Krynetskaia, W Yang, M Cheok, D Pei, Y Fan, ...
Nature medicine 17 (10), 1298-1303, 2011
1392011
Thiopurine pathway
G Zaza, M Cheok, N Krynetskaia, C Thorn, G Stocco, JM Hebert, ...
Pharmacogenetics and genomics 20 (9), 573-574, 2010
1272010
A cellular hierarchy framework for understanding heterogeneity and predicting drug response in acute myeloid leukemia
AGX Zeng, S Bansal, L Jin, A Mitchell, WC Chen, HA Abbas, ...
Nature medicine 28 (6), 1212-1223, 2022
1232022
IDH1/2 but not DNMT3A mutations are suitable targets for minimal residual disease monitoring in acute myeloid leukemia patients: a study by the Acute Leukemia French Association
H Debarri, D Lebon, C Roumier, M Cheok, A Marceau-Renaut, O Nibourel, ...
Oncotarget 6 (39), 42345, 2015
1192015
In vivo response to methotrexate forecasts outcome of acute lymphoblastic leukemia and has a distinct gene expression profile
MJ Sorich, N Pottier, D Pei, W Yang, L Kager, G Stocco, C Cheng, ...
PLoS Medicine 5 (4), e83, 2008
972008
Pharmacogenetics in acute lymphoblastic leukemia
MH Cheok, N Pottier, L Kager, WE Evans
Seminars in hematology 46 (1), 39-51, 2009
932009
Defective NK cells in acute myeloid leukemia patients at diagnosis are associated with blast transcriptional signatures of immune evasion
Z Khaznadar, N Boissel, S Agaugué, G Henry, M Cheok, M Vignon, ...
The Journal of Immunology 195 (6), 2580-2590, 2015
812015
The SWI/SNF chromatin-remodeling complex and glucocorticoid resistance in acute lymphoblastic leukemia
N Pottier, W Yang, M Assem, JC Panetta, D Pei, SW Paugh, C Cheng, ...
JNCI: Journal of the National Cancer Institute 100 (24), 1792-1803, 2008
732008
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