Phospho-dependent regulation of SAMHD1 oligomerisation couples catalysis and restriction LH Arnold, HCT Groom, S Kunzelmann, D Schwefel, SJ Caswell, ... PLoS pathogens 11 (10), e1005194, 2015 | 114 | 2015 |
The interface between catalytic and hemopexin domains in matrix metalloproteinase-1 conceals a collagen binding exosite LH Arnold, LE Butt, SH Prior, CM Read, GB Fields, AR Pickford Journal of Biological Chemistry 286 (52), 45073-45082, 2011 | 61 | 2011 |
A continuous enzyme-coupled assay for triphosphohydrolase activity of HIV-1 restriction factor SAMHD1 LH Arnold, S Kunzelmann, MR Webb, IA Taylor Antimicrobial agents and chemotherapy 59 (1), 186-192, 2015 | 49 | 2015 |
Crystal structures of SAMHD1 inhibitor complexes reveal the mechanism of water-mediated dNTP hydrolysis ER Morris, SJ Caswell, S Kunzelmann, LH Arnold, AG Purkiss, G Kelly, ... Nature communications 11 (1), 3165, 2020 | 30 | 2020 |