An in vitro cell irradiation protocol for testing photopharmaceuticals and the effect of blue, green, and red light on human cancer cell lines SL Hopkins, B Siewert, SHC Askes, P Veldhuizen, R Zwier, M Heger, ... Photochemical & Photobiological Sciences 15 (5), 644-653, 2016 | 114 | 2016 |
Synthesis and antimicrobial activity of (E) stilbene derivatives S Albert, R Horbach, HB Deising, B Siewert, R Csuk Bioorganic & medicinal chemistry 19 (17), 5155-5166, 2011 | 95 | 2011 |
Towards cytotoxic and selective derivatives of maslinic acid B Siewert, E Pianowski, A Obernauer, R Csuk Bioorganic & Medicinal Chemistry 22 (1), 594-615, 2014 | 93 | 2014 |
Synthesis and antitumor activity of ring A modified glycyrrhetinic acid derivatives R Csuk, S Schwarz, B Siewert, R Kluge, D Ströhl European journal of medicinal chemistry 46 (11), 5356-5369, 2011 | 86 | 2011 |
The photoactivity of natural products–an overlooked potential of phytomedicines? B Siewert, H Stuppner Phytomedicine 60, 152985, 2019 | 78 | 2019 |
Green light-induced apoptosis in cancer cells by a tetrapyridyl ruthenium prodrug offering two trans coordination sites VHS Van Rixel, B Siewert, SL Hopkins, SHC Askes, A Busemann, ... Chemical science 7 (8), 4922-4929, 2016 | 77 | 2016 |
Synthesis, encapsulation and antitumor activity of new betulin derivatives R Csuk, A Barthel, R Sczepek, B Siewert, S Schwarz Archiv der Pharmazie 344 (1), 37-49, 2011 | 73 | 2011 |
The chemical and biological potential of C ring modified triterpenoids B Siewert, J Wiemann, A Köwitsch, R Csuk European journal of medicinal chemistry 72, 84-101, 2014 | 64 | 2014 |
Esters and amides of maslinic acid trigger apoptosis in human tumor cells and alter their mode of action with respect to the substitution pattern at C-28 B Siewert, E Pianowski, R Csuk European Journal of Medicinal Chemistry 70, 259-272, 2013 | 63 | 2013 |
Cytotoxic betulin-derived hydroxypropargylamines trigger apoptosis R Csuk, R Sczepek, B Siewert, C Nitsche Bioorganic & medicinal chemistry 21 (2), 425-435, 2013 | 49 | 2013 |
Incorporation of a Michael acceptor enhances the antitumor activity of triterpenoic acids L Heller, S Schwarz, V Perl, A Köwitsch, B Siewert, R Csuk European Journal of Medicinal Chemistry 101, 391-399, 2015 | 44 | 2015 |
Synthesis of Antitumor‐Active Betulinic Acid‐Derived Hydroxypropargylamines by Copper‐Catalyzend Mannich Reactions R Csuk, C Nitsche, R Sczepek, S Schwarz, B Siewert Archiv der Pharmazie 346 (3), 232-246, 2013 | 41 | 2013 |
Tormentic acid derivatives: Synthesis and apoptotic activity R Csuk, B Siewert, C Dressel, R Schäfer European journal of medicinal chemistry 56, 237-245, 2012 | 40 | 2012 |
Alkylidene branched lupane derivatives: Synthesis and antitumor activity R Csuk, S Stark, C Nitsche, A Barthel, B Siewert European journal of medicinal chemistry 53, 337-345, 2012 | 40 | 2012 |
Synthesis and biological evaluation of novel (E) stilbene-based antitumor agents R Csuk, S Albert, B Siewert, S Schwarz European journal of medicinal chemistry 54, 669-678, 2012 | 38 | 2012 |
Chemical swarming: depending on concentration, an amphiphilic ruthenium polypyridyl complex induces cell death via two different mechanisms B Siewert, VHS van Rixel, EJ van Rooden, SL Hopkins, MJB Moester, ... Chemistry–A European Journal 22 (31), 10960-10968, 2016 | 37 | 2016 |
A “natural” approach: synthesis and cytoxicity of monodesmosidic glycyrrhetinic acid glycosides S Schwarz, B Siewert, NM Xavier, AR Jesus, AP Rauter, R Csuk European Journal of Medicinal Chemistry 72, 78-83, 2014 | 35 | 2014 |
Turning on the red phosphorescence of a [Ru (tpy)(bpy)(Cl)] Cl complex by amide substitution: Self-aggregation, toxicity, and cellular localization of an emissive ruthenium … B Siewert, M Langerman, Y Hontani, JTM Kennis, VHS Van Rixel, ... Chemical communications 53 (81), 11126-11129, 2017 | 33 | 2017 |
Membrane damaging activity of a maslinic acid analog B Siewert, R Csuk European journal of medicinal chemistry 74, 1-6, 2014 | 33 | 2014 |
Synthesis and Biological Evaluation of Antitumor‐Active Arglabin Derivatives R Csuk, A Heinold, B Siewert, S Schwarz, A Barthel, R Kluge, D Ströhl Archiv der Pharmazie 345 (3), 215-222, 2012 | 31 | 2012 |