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Ian Sabroe
Ian Sabroe
Verified email at sheffield.ac.uk
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Toll-like receptor (TLR) 2 and TLR4 in human peripheral blood granulocytes: a critical role for monocytes in leukocyte lipopolysaccharide responses
I Sabroe, EC Jones, LR Usher, MKB Whyte, SK Dower
The Journal of Immunology 168 (9), 4701-4710, 2002
4992002
ASPIRE registry: assessing the Spectrum of Pulmonary hypertension Identified at a REferral centre
J Hurdman, R Condliffe, CA Elliot, C Davies, C Hill, JM Wild, D Capener, ...
European Respiratory Journal 39 (4), 945-955, 2012
4952012
Selective roles for Toll-like receptor (TLR) 2 and TLR4 in the regulation of neutrophil activation and life span
I Sabroe, LR Prince, EC Jones, MJ Horsburgh, SJ Foster, SN Vogel, ...
The Journal of Immunology 170 (10), 5268-5275, 2003
4702003
Toll-like receptors in health and disease: complex questions remain
I Sabroe, RC Read, MKB Whyte, DH Dockrell, SN Vogel, SK Dower
The journal of immunology 171 (4), 1630-1635, 2003
3202003
The role of TLRs in neutrophil activation
LR Prince, MK Whyte, I Sabroe, LC Parker
Current opinion in pharmacology 11 (4), 397-403, 2011
2972011
The role of TLR activation in inflammation
I Sabroe, LC Parker, SK Dower, MKB Whyte
The Journal of Pathology: A Journal of the Pathological Society of Great …, 2008
2952008
Translational mini-review series on Toll-like receptors: networks regulated by Toll-like receptors mediate innate and adaptive immunity
LC Parker, LR Prince, I Sabroe
Clinical & Experimental Immunology 147 (2), 199-207, 2007
2942007
Eotaxin (CCL11) and eotaxin-2 (CCL24) induce recruitment of eosinophils, basophils, neutrophils, and macrophages as well as features of early-and late-phase allergic reactions …
A Menzies-Gow, S Ying, I Sabroe, VL Stubbs, D Soler, TJ Williams, ...
The Journal of Immunology 169 (5), 2712-2718, 2002
2822002
Invited review: Tolerance to microbial TLR ligands: Molecular mechanisms and relevance to disease
AE Medvedev, I Sabroe, JD Hasday, SN Vogel
Journal of endotoxin research 12 (3), 133-150, 2006
2762006
A small molecule antagonist of chemokine receptors CCR1 and CCR3: potent inhibition of eosinophil function and CCR3-mediated HIV-1 entry
I Sabroe, MJ Peck, BJ Van Keulen, A Jorritsma, G Simmons, PR Clapham, ...
Journal of Biological Chemistry 275 (34), 25985-25992, 2000
2722000
The role of Toll-like receptors in the regulation of neutrophil migration, activation, and apoptosis
I Sabroe, SK Dower, MKB Whyte
Clinical infectious diseases 41 (Supplement_7), S421-S426, 2005
2692005
The expression and roles of Toll-like receptors in the biology of the human neutrophil
LC Parker, MKB Whyte, SK Dower, I Sabroe
Journal of leukocyte biology 77 (6), 886-892, 2005
2632005
The role of interleukin-8 and its receptors in inflammatory lung disease: implications for therapy
JE Pease, I Sabroe
American Journal of Respiratory Medicine 1, 19-25, 2002
2592002
Pulmonary hypertension in COPD: results from the ASPIRE registry
J Hurdman, R Condliffe, CA Elliot, A Swift, S Rajaram, C Davies, C Hill, ...
European Respiratory Journal 41 (6), 1292-1301, 2013
2512013
Differential regulation of eosinophil chemokine signaling via CCR3 and non-CCR3 pathways
I Sabroe, A Hartnell, LA Jopling, S Bel, PD Ponath, JE Pease, PD Collins, ...
The Journal of Immunology 162 (5), 2946-2955, 1999
2191999
Prolyl hydroxylase 3 (PHD3) is essential for hypoxic regulation of neutrophilic inflammation in humans and mice
SR Walmsley, ER Chilvers, AA Thompson, K Vaughan, HM Marriott, ...
The Journal of clinical investigation 121 (3), 1053-1063, 2011
1992011
Eotaxin is specifically cleaved by hookworm metalloproteases preventing its action in vitro and in vivo
FJ Culley, A Brown, DM Conroy, I Sabroe, DI Pritchard, TJ Williams
The Journal of Immunology 165 (11), 6447-6453, 2000
1822000
Toll-like receptor (TLR) 2 and TLR4 agonists regulate CCR expression in human monocytic cells
LC Parker, MKB Whyte, SN Vogel, SK Dower, I Sabroe
The Journal of Immunology 172 (8), 4977-4986, 2004
1812004
Agonists of toll-like receptor (TLR) 2 and TLR4 are unable to modulate platelet activation by adenosine diphosphate and platelet activating factor
JR Ward, L Bingle, HM Judge, SB Brown, RF Storey, MKB Whyte, ...
Thrombosis and haemostasis 94 (10), 831-838, 2005
1792005
Pulmonary hypertension: diagnosis and management
DG Kiely, CA Elliot, I Sabroe, R Condliffe
Bmj 346, 2013
1702013
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Articles 1–20