| Structural basis for RNA replication by the hepatitis C virus polymerase TC Appleby, JK Perry, E Murakami, O Barauskas, J Feng, A Cho, D Fox III, ... Science 347 (6223), 771-775, 2015 | 330 | 2015 |
| Combining Functional and Structural Genomics to Sample the Essential Burkholderia Structome L Baugh, LA Gallagher, R Patrapuvich, MC Clifton, AS Gardberg, ... PloS one 8 (1), e53851, 2013 | 139 | 2013 |
| Increasing the structural coverage of tuberculosis drug targets L Baugh, I Phan, DW Begley, MC Clifton, B Armour, DM Dranow, ... Tuberculosis 95 (2), 142-148, 2015 | 121 | 2015 |
| Rif1 provides a new DNA‐binding interface for the Bloom syndrome complex to maintain normal replication D Xu, P Muniandy, E Leo, J Yin, S Thangavel, X Shen, M Ii, K Agama, ... The EMBO journal 29 (18), 3140-3155, 2010 | 107 | 2010 |
| Harnessing calcineurin-FK506-FKBP12 crystal structures from invasive fungal pathogens to develop antifungal agents PR Juvvadi, D Fox, BG Bobay, MJ Hoy, S Gobeil, RA Venters, Z Chang, ... Nature communications 10 (1), 1-18, 2019 | 93 | 2019 |
| Small molecules that inhibit TNF signalling by stabilising an asymmetric form of the trimer J O’Connell, J Porter, B Kroeplien, T Norman, S Rapecki, R Davis, ... Nature communications 10 (1), 1-12, 2019 | 78 | 2019 |
| A ubiquitin-binding protein, FAAP20, links RNF8-mediated ubiquitination to the Fanconi anemia DNA repair network Z Yan, R Guo, M Paramasivam, W Shen, C Ling, D Fox III, Y Wang, ... Molecular cell 47 (1), 61-75, 2012 | 77 | 2012 |
| RecQL5 promotes genome stabilization through two parallel mechanisms—interacting with RNA polymerase II and acting as a helicase MN Islam, D Fox III, R Guo, T Enomoto, W Wang Molecular and cellular biology 30 (10), 2460-2472, 2010 | 77 | 2010 |
| Design and synthesis of selective phosphodiesterase 4D (PDE4D) allosteric inhibitors for the treatment of fragile X syndrome and other brain disorders ME Gurney, RA Nugent, X Mo, JA Sindac, TJ Hagen, D Fox III, ... Journal of medicinal chemistry 62 (10), 4884-4901, 2019 | 49 | 2019 |
| HGT in the human and skin commensal Malassezia: A bacterially derived flavohemoglobin is required for NO resistance and host interaction G Ianiri, MA Coelho, F Ruchti, F Sparber, TJ McMahon, C Fu, M Bolejack, ... Proceedings of the National Academy of Sciences 117 (27), 15884-15894, 2020 | 34 | 2020 |
| Insight into small molecule binding to the neonatal Fc receptor by X-ray crystallography and 100 kHz magic-angle-spinning NMR D Stöppler, A Macpherson, S Smith-Penzel, N Basse, F Lecomte, ... PLoS biology 16 (5), e2006192, 2018 | 32 | 2018 |
| A structural biology approach enables the development of antimicrobials targeting bacterial immunophilins DW Begley, D Fox III, D Jenner, C Juli, PG Pierce, J Abendroth, M Muruthi, ... Antimicrobial agents and chemotherapy 58 (3), 1458-1467, 2014 | 29 | 2014 |
| Structure-guided synthesis of FK506 and FK520 analogs with increased selectivity exhibit in vivo therapeutic efficacy against C. neoformans MJ Hoy, E Park, H Lee, WY Lim, DC Cole, ND DeBouver, BG Bobay, ... bioRxiv, 2022 | 10 | 2022 |
| Broad-spectrum in vitro activity of macrophage infectivity potentiator inhibitors against Gram-negative bacteria and Leishmania major J Iwasaki, DD Lorimer, M Vivoli-Vega, EA Kibble, CS Peacock, ... Journal of Antimicrobial Chemotherapy, Art. dkac065, 2022 | 9 | 2022 |
| Structural Characterization of the Reaction and Substrate Specificity Mechanisms of Pathogenic Fungal Acetyl-CoA Synthetases AJ Jezewski, KM Alden, TE Esan, ND DeBouver, J Abendroth, JC Bullen, ... ACS Chemical Biology 16 (8), 1587-1599, 2021 | 5 | 2021 |
| Genetic interaction analysis reveals that Cryptococcus neoformans utilizes multiple acetyl-CoA-generating pathways during infection KM Alden, AJ Jezewski, SR Beattie, D Fox, DJ Krysan bioRxiv, 2022 | 3 | 2022 |
| Horizontal gene transfer in the human and skin commensal Malassezia: a bacterially-derived flavohemoglobin is required for NO resistance and host interaction G Ianiri, MA Coelho, F Ruchti, F Sparber, TJ McMahon, C Fu, M Bolejack, ... bioRxiv, 2020 | 2 | 2020 |
| NOVEL STRUCTURE OF FLAVOHEMOGLOBIN FROM MALASSEZIA YAMATOENSIS DETERMINED BY SAD PHASING M Bolejack, J Abendroth, D Fox III, T Edwards, P Myler, S Mayclin PROTEIN SCIENCE 28, 187-187, 2019 | | 2019 |
| Novel FK506 analog exhibits anti-fungal activity against Cryptococcus neoformans in vitro and in an animal model MJ Hoy, D Fox, J Wheaton, M Mutz, WJ Steinbach, M Ciofani, J Heitman MEDICAL MYCOLOGY 56, S139-S139, 2018 | | 2018 |
| Discovery and development of novel small molecule modulators of TNF alpha signalling D Brookings, R Alexander, T Arakaki, J Bentley, T Bourne, J Brown, ... ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 255, 2018 | | 2018 |
