| Role of AMP-activated protein kinase in mechanism of metformin action G Zhou, R Myers, Y Li, Y Chen, X Shen, J Fenyk-Melody, M Wu, J Ventre, ... The Journal of clinical investigation 108 (8), 1167-1174, 2001 | 6776 | 2001 |
| Brown adipose tissue regulates glucose homeostasis and insulin sensitivity KI Stanford, RJW Middelbeek, KL Townsend, D An, EB Nygaard, ... The Journal of clinical investigation 123 (1), 2012 | 1279 | 2012 |
| Metformin increases AMP-activated protein kinase activity in skeletal muscle of subjects with type 2 diabetes N Musi, MF Hirshman, J Nygren, M Svanfeldt, P Bavenholm, ... Diabetes 51 (7), 2074-2081, 2002 | 1065 | 2002 |
| Evidence for 5′ AMP-activated protein kinase mediation of the effect of muscle contraction on glucose transport T Hayashi, MF Hirshman, EJ Kurth, WW Winder, LJ Goodyear Diabetes 47 (8), 1369-1373, 1998 | 1031 | 1998 |
| Targeted disruption of the glucose transporter 4 selectively in muscle causes insulin resistance and glucose intolerance A Zisman, OD Peroni, ED Abel, MD Michael, F Mauvais-Jarvis, BB Lowell, ... Nature medicine 6 (8), 924-928, 2000 | 969 | 2000 |
| 5'AMP-activated protein kinase activation causes GLUT4 translocation in skeletal muscle. EJ Kurth-Kraczek, MF Hirshman, LJ Goodyear, WW Winder Diabetes 48 (8), 1667-1671, 1999 | 920 | 1999 |
| Restoring systemic GDF11 levels reverses age-related dysfunction in mouse skeletal muscle M Sinha, YC Jang, J Oh, D Khong, EY Wu, R Manohar, C Miller, ... Science 344 (6184), 649-652, 2014 | 908 | 2014 |
| Acute exercise induces GLUT4 translocation in skeletal muscle of normal human subjects and subjects with type 2 diabetes. JW Kennedy, MF Hirshman, EV Gervino, JV Ocel, RA Forse, SJ Hoenig, ... Diabetes 48 (5), 1192-1197, 1999 | 601 | 1999 |
| Highly efficient, functional engraftment of skeletal muscle stem cells in dystrophic muscles M Cerletti, S Jurga, CA Witczak, MF Hirshman, JL Shadrach, LJ Goodyear, ... Cell 134 (1), 37-47, 2008 | 552 | 2008 |
| Metabolic stress and altered glucose transport: activation of AMP-activated protein kinase as a unifying coupling mechanism. T Hayashi, MF Hirshman, N Fujii, SA Habinowski, LA Witters, ... Diabetes 49 (4), 527-531, 2000 | 548 | 2000 |
| Muscle-specific PPARγ-deficient mice develop increased adiposity and insulin resistance but respond to thiazolidinediones AW Norris, L Chen, SJ Fisher, I Szanto, M Ristow, AC Jozsi, MF Hirshman, ... The Journal of clinical investigation 112 (4), 608-618, 2003 | 540 | 2003 |
| Enhanced peripheral and splanchnic insulin sensitivity in NIDDM men after single bout of exercise JT Devlin, M Hirshman, ED Horton, ES Horton Diabetes 36 (4), 434-439, 1987 | 511 | 1987 |
| AMP-activated protein kinase (AMPK) is activated in muscle of subjects with type 2 diabetes during exercise N Musi, N Fujii, MF Hirshman, I Ekberg, S Froberg, O Ljungqvist, A Thorell, ... Diabetes 50 (5), 921-927, 2001 | 507 | 2001 |
| Exercise induces isoform-specific increase in 5′ AMP-activated protein kinase activity in human skeletal muscle N Fujii, T Hayashi, MF Hirshman, JT Smith, SA Habinowski, L Kaijser, ... Biochemical and biophysical research communications 273 (3), 1150-1155, 2000 | 479 | 2000 |
| Distinct signals regulate AS160 phosphorylation in response to insulin, AICAR, and contraction in mouse skeletal muscle HF Kramer, CA Witczak, N Fujii, N Jessen, EB Taylor, DE Arnolds, ... Diabetes 55 (7), 2067-2076, 2006 | 410 | 2006 |
| Skeletal muscle adaptation to exercise training: AMP-activated protein kinase mediates muscle fiber type shift KSC Rockl, MF Hirshman, J Brandauer, N Fujii, LA Witters, LJ Goodyear Diabetes 56 (8), 2062-2069, 2007 | 395 | 2007 |
| The cold-induced lipokine 12, 13-diHOME promotes fatty acid transport into brown adipose tissue MD Lynes, LO Leiria, M Lundh, A Bartelt, F Shamsi, TL Huang, ... Nature medicine 23 (5), 631-637, 2017 | 376 | 2017 |
| Increased adenosine monophosphate–activated protein kinase activity in rat hearts with pressure-overload hypertrophy R Tian, N Musi, J D’Agostino, MF Hirshman, LJ Goodyear Circulation 104 (14), 1664-1669, 2001 | 362 | 2001 |
| AS160 regulates insulin-and contraction-stimulated glucose uptake in mouse skeletal muscle HF Kramer, CA Witczak, EB Taylor, N Fujii, MF Hirshman, LJ Goodyear Journal of Biological Chemistry 281 (42), 31478-31485, 2006 | 357 | 2006 |
| Reduced expression of the murine p85α subunit of phosphoinositide 3-kinase improves insulin signaling and ameliorates diabetes F Mauvais-Jarvis, K Ueki, DA Fruman, MF Hirshman, K Sakamoto, ... The Journal of clinical investigation 109 (1), 141-149, 2002 | 351 | 2002 |
