The MutT proteins or “Nudix” hydrolases, a family of versatile, widely distributed,“housecleaning” enzymes MJ Bessman, DN Frick, SF O'Handley Journal of Biological Chemistry 271 (41), 25059-25062, 1996 | 789 | 1996 |
Atomic structure of the DNA repair [4Fe-4S] enzyme endonuclease III CF Kuo, DE McRee, CL Fisher, SF O'Handley, RP Cunningham, ... Science 258 (5081), 434-440, 1992 | 394 | 1992 |
Structural characterization of an N-acetyl-2-aminofluorene (AAF) modified DNA oligomer by NMR, energy minimization, and molecular dynamics SF O'Handley, DG Sanford, R Xu, CC Lester, BE Hingerty, S Broyde, ... Biochemistry 32 (10), 2481-2497, 1993 | 183 | 1993 |
Studies on the ADP-ribose pyrophosphatase subfamily of the nudix hydrolases and tentative identification of trgB, a gene associated with tellurite resistance CA Dunn, SF O'Handley, DN Frick, MJ Bessman Journal of Biological Chemistry 274 (45), 32318-32324, 1999 | 178 | 1999 |
The role of the iron-sulfur cluster in Escherichia coli endonuclease III. A resonance Raman study. W Fu, S O'Handley, RP Cunningham, MK Johnson Journal of Biological Chemistry 267 (23), 16135-16137, 1992 | 113 | 1992 |
Orf186 represents a new member of the Nudix hydrolases, active on adenosine (5′) triphospho (5′) adenosine, ADP-ribose, and NADH SF O'Handley, DN Frick, CA Dunn, MJ Bessman Journal of Biological Chemistry 273 (6), 3192-3197, 1998 | 89 | 1998 |
Escherichia coli orf17 codes for a nucleoside triphosphate pyrophosphohydrolase member of the MutT family of proteins: cloning, purification, and characterization of the enzyme SF O'Handley, DN Frick, LC Bullions, AS Mildvan, MJ Bessman Journal of Biological Chemistry 271 (40), 24649-24654, 1996 | 70 | 1996 |
Structure and mechanism of MT-ADPRase, a nudix hydrolase from Mycobacterium tuberculosis LW Kang, SB Gabelli, JE Cunningham, SF O'Handley, LM Amzel Structure 11 (8), 1015-1023, 2003 | 68 | 2003 |
Identification and characterization of the Nudix hydrolase from the Archaeon, Methanococcus jannaschii, as a highly specific ADP-ribose pyrophosphatase S Sheikh, SF O'Handley, CA Dunn, MJ Bessman Journal of Biological Chemistry 273 (33), 20924-20928, 1998 | 66 | 1998 |
Orf135 from Escherichia coli is a Nudix hydrolase specific for CTP, dCTP, and 5-methyl-dCTP SF O'Handley, CA Dunn, MJ Bessman Journal of Biological Chemistry 276 (8), 5421-5426, 2001 | 53 | 2001 |
Endonuclease III interactions with DNA substrates. 1. Binding and footprinting studies with oligonucleotides containing a reduced apyrimidinic site S O'Handley, CP Scholes, RP Cunningham Biochemistry 34 (8), 2528-2536, 1995 | 51 | 1995 |
Three new Nudix hydrolases from Escherichia coli W Xu, CA Dunn, SF O'handley, DL Smith, MJ Bessman Journal of Biological Chemistry 281 (32), 22794-22798, 2006 | 38 | 2006 |
YZGD from Paenibacillus thiaminolyticus, a pyridoxal phosphatase of the HAD (haloacid dehalogenase) superfamily and a versatile member of the Nudix … IM Tirrell, JL Wall, CJ Daley, SJ Denial, FG Tennis, KG Galens, ... Biochemical Journal 394 (3), 665-674, 2006 | 18 | 2006 |
Using protein function prediction to promote hypothesis-driven thinking in undergraduate biochemistry education PA Craig, T Anderson, HJ Bernstein, J Herbert, C Daubner, A Goodman, ... The chemist 91 (1), 2018 | 5 | 2018 |
Kinetic and mutational studies of the adenosine diphosphate ribose hydrolase from Mycobacterium tuberculosis SF O’Handley, P Thirawatananond, LW Kang, JE Cunningham, JA Leyva, ... Journal of bioenergetics and biomembranes 48, 557-567, 2016 | 4 | 2016 |
Insights into the substrate specificity of the MutT pyrophosphohydrolase using structural analogues of 8-oxo-2′-deoxyguanosine nucleotide ML Hamm, EJ McFadden, M Ghio, MAM Lindell, KS Gerien, SF O’Handley Bioorganic & medicinal chemistry letters 26 (8), 2014-2017, 2016 | 4 | 2016 |
Structural analysis of a carcinogen-modified DNA oligomer by NMR spectroscopy SF O'Handley University of Rochester. Department of Chemistry, 1991 | 3 | 1991 |
A Phosphoglycolate Phosphatase Virulence Factor from Staphylococcus aureus J Edwards, A Gehret, S O'Handley The FASEB Journal 29, 721.11, 2015 | 2 | 2015 |
Abstract 1349 A CTPase Nudix Hydrolase from Mycobacterium tuberculosis as a Potential Novel Antibiotic Target P Chen, M Soto, N Aikins, D Frick, J Thomas, S O'Handley Journal of Biological Chemistry 300 (3), 2024 | | 2024 |
Abstract 1995 Characterization of Diadenosine Polyphosphatases of the Nudix Hydrolase Superfamily in M. tuberculosis and M. leprae A Seyler, E Reilly, P Zhu, S O'Handley Journal of Biological Chemistry 300 (3), 2024 | | 2024 |