Denis Schapiro
Denis Schapiro
Group Leader at the Heidelberg University Hospital
Verified email at - Homepage
Cited by
Cited by
Highly multiplexed imaging of tumor tissues with subcellular resolution by mass cytometry
C Giesen*, HAO Wang*, D Schapiro, N Zivanovic, A Jacobs, B Hattendorf, ...
Nature methods 11 (4), 417-422 -- *Authors contributed equally, 2014
High-definition spatial transcriptomics for in situ tissue profiling
S Vickovic*, G Eraslan*, F Salmén*, J Klughammer*, L Stenbeck*, ...
Nature methods 16 (10), 987-990 -- *Authors contributed equally, 2019
histoCAT: analysis of cell phenotypes and interactions in multiplex image cytometry data
D Schapiro, HW Jackson, S Raghuraman, JR Fischer, VRT Zanotelli, ...
Nature methods 14 (9), 873-876, 2017
A molecular single-cell lung atlas of lethal COVID-19
JC Melms, J Biermann, H Huang, Y Wang, A Nair, S Tagore, I Katsyv, ...
Nature 595 (7865), 114-119, 2021
The human tumor atlas network: charting tumor transitions across space and time at single-cell resolution
O Rozenblatt-Rosen, A Regev, P Oberdoerffer, T Nawy, A Hupalowska, ...
Cell 181 (2), 236-249, 2020
Simultaneous multiplexed imaging of mRNA and proteins with subcellular resolution in breast cancer tissue samples by mass cytometry
D Schulz, VRT Zanotelli, JR Fischer, D Schapiro, S Engler, XK Lun, ...
Cell systems 6 (1), 25-36. e5, 2018
Spatial multi-omic map of human myocardial infarction
C Kuppe, RO Ramirez Flores, Z Li, S Hayat, RT Levinson, X Liao, ...
Nature 608 (7924), 766-777, 2022
A map of human type 1 diabetes progression by imaging mass cytometry
N Damond, S Engler, VRT Zanotelli, D Schapiro, CH Wasserfall, ...
Cell metabolism 29 (3), 755-768. e5, 2019
Immunogenomic profiling determines responses to combined PARP and PD-1 inhibition in ovarian cancer
A Färkkilä, DC Gulhan, J Casado, CA Jacobson, H Nguyen, ...
Nature communications 11 (1), 1459, 2020
Single-nucleus and spatial transcriptome profiling of pancreatic cancer identifies multicellular dynamics associated with neoadjuvant treatment
WL Hwang, KA Jagadeesh, JA Guo, HI Hoffman, P Yadollahpour, ...
Nature genetics 54 (8), 1178-1191, 2022
Modeling cell-cell interactions from spatial molecular data with spatial variance component analysis
D Arnol, D Schapiro, B Bodenmiller, J Saez-Rodriguez, O Stegle
Cell reports 29 (1), 202-211. e6, 2019
MCMICRO: a scalable, modular image-processing pipeline for multiplexed tissue imaging
D Schapiro, A Sokolov, C Yapp, YA Chen, JL Muhlich, J Hess, ...
Nature methods 19 (3), 311-315, 2022
Receptor-driven ERK pulses reconfigure MAPK signaling and enable persistence of drug-adapted BRAF-mutant melanoma cells
L Gerosa, C Chidley, F Fröhlich, G Sanchez, SK Lim, J Muhlich, JY Chen, ...
Cell systems 11 (5), 478-494. e9, 2020
Explainable multiview framework for dissecting spatial relationships from highly multiplexed data
J Tanevski, ROR Flores, A Gabor, D Schapiro, J Saez-Rodriguez
Genome biology 23 (1), 97, 2022
Evolution of delayed resistance to immunotherapy in a melanoma responder
D Liu, JR Lin, EJ Robitschek, GG Kasumova, A Heyde, A Shi, A Kraya, ...
Nature medicine 27 (6), 985-992, 2021
Dissecting the treatment-naive ecosystem of human melanoma brain metastasis
J Biermann, JC Melms, AD Amin, Y Wang, LA Caprio, A Karz, S Tagore, ...
Cell 185 (14), 2591-2608. e30, 2022
Automatic single cell segmentation on highly multiplexed tissue images
PJ Schüffler*, D Schapiro*, C Giesen, HAO Wang, B Bodenmiller, ...
Cytometry Part A 87 (10), 936-942 -- *Authors contributed equally, 2015
Highly multiplexed immunofluorescence images and single-cell data of immune markers in tonsil and lung cancer
R Rashid, G Gaglia, YA Chen, JR Lin, Z Du, Z Maliga, D Schapiro, C Yapp, ...
Scientific data 6 (1), 323, 2019
High-dimensional phenotyping identifies age-emergent cells in human mammary epithelia
FAP Vatter, D Schapiro, H Chang, AD Borowsky, JK Lee, B Parvin, ...
Cell reports 23 (4), 1205-1219, 2018
Influence of node abundance on signaling network state and dynamics analyzed by mass cytometry
XK Lun, VRT Zanotelli, JD Wade, D Schapiro, M Tognetti, N Dobberstein, ...
Nature biotechnology 35 (2), 164-172, 2017
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