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Sean Cullum
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Structural basis of the negative allosteric modulation of 5-BDBD at human P2X4 receptors
S Bidula, IB Nadzirin, M Cominetti, H Hickey, SA Cullum, M Searcey, ...
Molecular pharmacology 101 (1), 33-44, 2022
142022
Combined docking and machine learning identify key molecular determinants of ligand pharmacological activity on β2 adrenoceptor
M Jiménez‐Rosés, BA Morgan, M Jimenez Sigstad, TDZ Tran, ...
Pharmacology Research & Perspectives 10 (5), e00994, 2022
8*2022
Kinetic analysis of endogenous β2‐adrenoceptor‐mediated cAMP GloSensor™ responses in HEK293 cells
SA Cullum, DB Veprintsev, SJ Hill
British Journal of Pharmacology 180 (10), 1304-1315, 2023
52023
ThermoBRET: A Ligand‐Engagement Nanoscale Thermostability Assay Applied to GPCRs
BL Hoare, DN Tippett, A Kaur, SA Cullum, T Miljuš, EJ Koers, ...
ChemBioChem 25 (2), e202300459, 2024
1*2024
Mechano-sensitivity of β2-adrenoceptors enhances constitutive activation of cAMP generation that is inhibited by inverse agonists
SA Cullum, S Platt, N Dale, OC Isaac, ES Wragg, M Soave, DB Veprintsev, ...
Communications Biology 7 (1), 417, 2024
2024
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Articles 1–5