| Flipping in the pore: discovery of dual inhibitors that bind in different orientations to the wild-type versus the amantadine-resistant S31N mutant of the influenza A virus M2 … Y Wu, B Canturk, H Jo, C Ma, E Gianti, ML Klein, LH Pinto, RA Lamb, ... Journal of the American Chemical Society 136 (52), 17987-17995, 2014 | 101 | 2014 |
| Computational analysis of EBNA1 “druggability” suggests novel insights for Epstein-Barr virus inhibitor design E Gianti, TE Messick, PM Lieberman, RJ Zauhar Journal of computer-aided molecular design 30, 285-303, 2016 | 43 | 2016 |
| Does Proton Conduction in the Voltage-Gated H+ Channel hHv1 Involve Grotthuss-Like Hopping via Acidic Residues? S van Keulen, E Gianti, V Carnevale, M Klein, U Rothlisberger, ... J Phys Chem B, DOI:10.1021/acs.jpcb.6b08339, 2016 | 41 | 2016 |
| Allosteric inhibitors of the main protease of SARS-CoV-2 SK Samrat, J Xu, X Xie, E Gianti, H Chen, J Zou, JG Pattis, K Elokely, ... Antiviral research 205, 105381, 2022 | 40 | 2022 |
| Sites Contributing to TRPA1 Activation by the Anesthetic Propofol Identified by Photoaffinity Labeling GR Woll KA, Skinner KA, Gianti E, Bhanu NV, Garcia BA, Carnevale V, Eckenhoff RG Biophys J, DOI:10.1016/j.bpj.2017.08.040, 2017 | 36* | 2017 |
| On the role of water density fluctuations in the inhibition of a proton channel E Gianti, L Delemotte, ML Klein, V Carnevale Proceedings of the National Academy of Sciences 113 (52), E8359-E8368, 2016 | 35 | 2016 |
| Synthesis and biological evaluation of N-hydroxyphenylacrylamides and N-hydroxypyridin-2-ylacrylamides as novel histone deacetylase inhibitors F Thaler, A Colombo, A Mai, R Amici, C Bigogno, R Boggio, A Cappa, ... Journal of Medicinal Chemistry 53 (2), 822-839, 2009 | 35 | 2009 |
| Hydrogen-bonded water molecules in the M2 channel of the influenza A virus guide the binding preferences of ammonium-based inhibitors E Gianti, V Carnevale, WF DeGrado, ML Klein, G Fiorin The Journal of Physical Chemistry B 119 (3), 1173-1183, 2015 | 34 | 2015 |
| Identification and selection of “privileged fragments” suitable for primary screening E Gianti, L Sartori Journal of Chemical Information and Modeling 48 (11), 2129-2139, 2008 | 31 | 2008 |
| Suppression of zika virus infection in the brain by the antiretroviral drug rilpivirine IK Sariyer, J Gordon, TH Burdo, HS Wollebo, E Gianti, M Donadoni, ... Molecular Therapy 27 (12), 2067-2079, 2019 | 28 | 2019 |
| TRPA1 modulation by piperidine carboxamides suggests an evolutionarily conserved binding site and gating mechanism T Chernov-Rogan, E Gianti, C Liu, E Villemure, AP Cridland, X Hu, ... Proceedings of the National Academy of Sciences 116 (51), 26008-26019, 2019 | 24 | 2019 |
| Dual regulation of TRPV1 channels by phosphatidylinositol via functionally distinct binding sites AT Yazici, E Gianti, MA Kasimova, BH Lee, V Carnevale, T Rohacs Journal of Biological Chemistry 296, 2021 | 21 | 2021 |
| Modeling androgen receptor flexibility: a binding mode hypothesis of CYP17 inhibitors/antiandrogens for prostate cancer therapy E Gianti, RJ Zauhar Journal of chemical information and modeling 52 (10), 2670-2683, 2012 | 21 | 2012 |
| Fragment-based Shape Signatures: a new tool for virtual screening and drug discovery RJ Zauhar, E Gianti, WJ Welsh Journal of Computer-Aided Molecular Design 27 (12), 1009-1036, 2013 | 19 | 2013 |
| Machine Learning at the Interface of Polymer Science and Biology: How Far Can We Go? E Gianti, S Percec Biomacromolecules 23 (3), 576-591, 2022 | 17 | 2022 |
| An SH2 domain model of STAT5 in complex with phospho-peptides define “STAT5 Binding Signatures” E Gianti, RJ Zauhar Journal of computer-aided molecular design 29, 451-470, 2015 | 17 | 2015 |
| Structure–activity relationships and drug design E Gianti, RJ Zauhar Remington, 129-153, 2021 | 11 | 2021 |
| Computational and functional studies of the PI (4, 5) P2 binding site of the TRPM3 ion channel reveal interactions with other regulators S Zhao, V Carnevale, M Gabrielle, E Gianti, T Rohacs Journal of Biological Chemistry 298 (11), 2022 | 8 | 2022 |
| Complex Helical Self-Organizations and Functions on All Length Scales. From Art, Architecture, Early Machines and Natural Phenomena to Biological and Synthetic Assemblies and … V Percec, J Adamson, E Gianti Supramolecular Nanotechnology, 2023 | 5 | 2023 |
| Computational approaches to studying voltage-gated ion channel modulation by general anesthetics E Gianti, V Carnevale Methods in Enzymology 602, 25-59, 2018 | 5 | 2018 |
Vincenzo CarnevaleiGEM & ICMS - Temple UniversityVerified email at temple.edu
