| Mitochondrial metabolism and ROS generation are essential for Kras-mediated tumorigenicity F Weinberg, R Hamanaka, WW Wheaton, S Weinberg, J Joseph, M Lopez, ... Proceedings of the National Academy of Sciences 107 (19), 8788-8793, 2010 | 1782 | 2010 |
| Single-cell transcriptomic analysis of human lung provides insights into the pathobiology of pulmonary fibrosis PA Reyfman, JM Walter, N Joshi, KR Anekalla, AC McQuattie-Pimentel, ... American journal of respiratory and critical care medicine 199 (12), 1517-1536, 2019 | 1003 | 2019 |
| Flow cytometric analysis of macrophages and dendritic cell subsets in the mouse lung AV Misharin, L Morales-Nebreda, GM Mutlu, GRS Budinger, H Perlman American journal of respiratory cell and molecular biology 49 (4), 503-510, 2013 | 898 | 2013 |
| Monocyte-derived alveolar macrophages drive lung fibrosis and persist in the lung over the life span AV Misharin, L Morales-Nebreda, PA Reyfman, CM Cuda, JM Walter, ... Journal of Experimental Medicine 214 (8), 2387-2404, 2017 | 867 | 2017 |
| The Qo site of the mitochondrial complex III is required for the transduction of hypoxic signaling via reactive oxygen species production EL Bell, TA Klimova, J Eisenbart, CT Moraes, MP Murphy, GRS Budinger, ... The Journal of cell biology 177 (6), 1029-1036, 2007 | 654 | 2007 |
| The role of macrophages in the resolution of inflammation S Watanabe, M Alexander, AV Misharin, GRS Budinger The Journal of clinical investigation 129 (7), 2619-2628, 2019 | 632 | 2019 |
| Minimizing oxidation and stable nanoscale dispersion improves the biocompatibility of graphene in the lung MC Duch, GRS Budinger, YT Liang, S Soberanes, D Urich, SE Chiarella, ... Nano letters 11 (12), 5201-5207, 2011 | 589 | 2011 |
| Circuits between infected macrophages and T cells in SARS-CoV-2 pneumonia RA Grant, L Morales-Nebreda, NS Markov, S Swaminathan, M Querrey, ... Nature 590 (7847), 635-641, 2021 | 586 | 2021 |
| Influenza virus-induced lung injury: pathogenesis and implications for treatment S Herold, C Becker, KM Ridge, GRS Budinger European Respiratory Journal 45 (5), 1463-1478, 2015 | 464 | 2015 |
| Hypoxic activation of AMPK is dependent on mitochondrial ROS but independent of an increase in AMP/ATP ratio BM Emerling, F Weinberg, C Snyder, Z Burgess, GM Mutlu, B Viollet, ... Free Radical Biology and Medicine 46 (10), 1386-1391, 2009 | 375 | 2009 |
| Mitochondrial reactive oxygen species regulate transforming growth factor-β signaling M Jain, S Rivera, EA Monclus, L Synenki, A Zirk, J Eisenbart, ... Journal of Biological Chemistry 288 (2), 770-777, 2013 | 359 | 2013 |
| The cellular basis for diverse responses to oxygen NS Chandel, GRS Budinger Free Radical Biology and Medicine 42 (2), 165-174, 2007 | 341 | 2007 |
| Ambient particulate matter accelerates coagulation via an IL-6–dependent pathway GM Mutlu, D Green, A Bellmeyer, CM Baker, Z Burgess, N Rajamannan, ... The Journal of clinical investigation 117 (10), 2952-2961, 2007 | 333 | 2007 |
| Hypoxic but not anoxic stabilization of HIF-1α requires mitochondrial reactive oxygen species C Schroedl, DS McClintock, GRS Budinger, NS Chandel American Journal of Physiology-Lung Cellular and Molecular Physiology 283 (5 …, 2002 | 332 | 2002 |
| Nonclassical Ly6C− monocytes drive the development of inflammatory arthritis in mice AV Misharin, CM Cuda, R Saber, JD Turner, AK Gierut, GK Haines, ... Cell reports 9 (2), 591-604, 2014 | 309 | 2014 |
| Toll-like receptor 4 signaling augments transforming growth factor-β responses: a novel mechanism for maintaining and amplifying fibrosis in scleroderma S Bhattacharyya, K Kelley, DS Melichian, Z Tamaki, F Fang, Y Su, G Feng, ... The American journal of pathology 182 (1), 192-205, 2013 | 284 | 2013 |
| Lung transplantation for patients with severe COVID-19 A Bharat, M Querrey, NS Markov, S Kim, C Kurihara, R Garza-Castillon, ... Science translational medicine 12 (574), eabe4282, 2020 | 275 | 2020 |
| Bcl-2 family members and functional electron transport chain regulate oxygen deprivation-induced cell death DS McClintock, MT Santore, VY Lee, J Brunelle, GRS Budinger, WX Zong, ... Molecular and cellular biology 22 (1), 94-104, 2002 | 275 | 2002 |
| Vimentin regulates activation of the NLRP3 inflammasome G Dos Santos, MR Rogel, MA Baker, JR Troken, D Urich, ... Nature communications 6 (1), 6574, 2015 | 246 | 2015 |
| Cellular respiration during hypoxia: role of cytochrome oxidase as the oxygen sensor in hepatocytes NS Chandel, GRS Budinger, SH Choe, PT Schumacker Journal of biological chemistry 272 (30), 18808-18816, 1997 | 245 | 1997 |
Gokhan M MutluProfessor of MedicineVerified email at uchicago.edu
