Follow
Kiran V. Mahasenan, PhD
Kiran V. Mahasenan, PhD
Kymera Therapeutics
Verified email at kymeratx.com - Homepage
Title
Cited by
Cited by
Year
Discoidin domain receptors: unique receptor tyrosine kinases in collagen-mediated signaling
HL Fu, RR Valiathan, R Arkwright, A Sohail, C Mihai, M Kumarasiri, ...
Journal of Biological Chemistry 288 (11), 7430-7437, 2013
2342013
Selective inhibition of protein arginine methyltransferase 5 blocks initiation and maintenance of B-cell transformation
L Alinari, KV Mahasenan, F Yan, V Karkhanis, JH Chung, EM Smith, ...
Blood 125 (16), 2530-2543, 2015
1622015
Carborane clusters in computational drug design: A comparative docking evaluation using AutoDock, FlexX, Glide, and Surflex
R Tiwari, K Mahasenan, R Pavlovicz, C Li, W Tjarks
Journal of chemical information and modeling 49 (6), 1581-1589, 2009
1092009
Validation of Matrix Metalloproteinase-9 (MMP-9) as a Novel Target for Treatment of Diabetic Foot Ulcers in Humans and Discovery of a Potent and Selective Small-Molecule MMP-9 …
TT Nguyen, D Ding, WR Wolter, RL Perez, MM Champion, ...
Journal of Medicinal Chemistry, 2018
1042018
Antitrypanosomal activity of 1, 2-dihydroquinolin-6-ols and their ester derivatives
J Fotie, M Kaiser, DA Delfín, J Manley, CS Reid, JM Paris, T Wenzler, ...
Journal of medicinal chemistry 53 (3), 966-982, 2010
982010
Shedding of discoidin domain receptor 1 by membrane-type matrix metalloproteinases
HL Fu, A Sohail, RR Valiathan, BD Wasinski, M Kumarasiri, ...
Journal of Biological Chemistry 288 (17), 12114-12129, 2013
922013
Conformational Dynamics in Penicillin-Binding Protein 2a of Methicillin-Resistant Staphylococcus aureus, Allosteric Communication Network and Enablement of …
KV Mahasenan, R Molina, R Bouley, MT Batuecas, JF Fisher, ...
Journal of the American Chemical Society 139 (5), 2102-2110, 2017
892017
Cyclic peptide inhibitors of HIV-1 capsid-human lysyl-tRNA synthetase interaction
V Dewan, T Liu, KM Chen, Z Qian, Y Xiao, L Kleiman, KV Mahasenan, ...
ACS Chemical Biology 7 (4), 761-769, 2012
552012
Structure and Cell Wall Cleavage by Modular Lytic Transglycosylase MltC of Escherichia coli
C Artola-Recolons, M Lee, N Bernardo-García, B Blázquez, D Hesek, ...
ACS chemical biology 9 (9), 2058-2066, 2014
522014
The quinazolinone allosteric inhibitor of PBP2a synergizes with piperacillin and tazobactam against methicillin-resistant Staphylococcus aureus
J Janardhanan, R Bouley, S Martínez-Caballero, Z Peng, ...
Antimicrobial agents and chemotherapy, AAC. 02637-18, 2019
482019
Three-dimensional QSAR analysis and design of new 1, 2, 4-oxadiazole antibacterials
E Leemans, KV Mahasenan, M Kumarasiri, E Spink, D Ding, PI O’Daniel, ...
Bioorganic & medicinal chemistry letters 26 (3), 1011-1015, 2016
482016
Synthesis, biological evaluation, and molecular modeling of 3, 5-substituted-N1-phenyl-N4, N4-di-n-butylsulfanilamides as antikinetoplastid antimicrotubule agents
TG George, MM Endeshaw, RE Morgan, KV Mahasenan, DA Delfín, ...
Bioorganic & medicinal chemistry 15 (18), 6071, 2007
482007
O-Phenyl Carbamate and Phenyl Urea Thiiranes as Selective Matrix Metalloproteinase-2 Inhibitors that Cross the Blood–Brain Barrier
M Gooyit, W Song, KV Mahasenan, K Lichtenwalter, MA Suckow, ...
Journal of medicinal chemistry 56 (20), 8139-8150, 2013
402013
Exolytic and endolytic turnover of peptidoglycan by lytic transglycosylase Slt of Pseudomonas aeruginosa
M Lee, MT Batuecas, S Tomoshige, T Domínguez-Gil, KV Mahasenan, ...
Proceedings of the National Academy of Sciences - USA, 2018
392018
Glycosylation at ASN211 regulates the activation state of the discoidin domain receptor 1 (DDR1)
HL Fu, RR Valiathan, L Payne, M Kumarasiri, KV Mahasenan, ...
Journal of Biological Chemistry 289 (13), 9275-9287, 2014
392014
Exploration of the Structural Space in 4(3H)-Quinazolinone Antibacterials
Y Qian, G Allegretta, J Janardhanan, Z Peng, KV Mahasenan, ...
Journal of Medicinal Chemistry, 2020
382020
Structural basis of denuded glycan recognition by SPOR domains in bacterial cell division
M Alcorlo, DA Dik, S De Benedetti, KV Mahasenan, M Lee, ...
Nature Communications 10 (1), 1-13, 2019
332019
Mechanism of the Escherichia coli MltE lytic transglycosylase, the cell-wall-penetrating enzyme for Type VI secretion system assembly
B Byun, KV Mahasenan, DA Dik, DR Marous, E Speri, M Kumarasiri, ...
Scientific reports 8 (1), 4110, 2018
332018
Allostery, Recognition of Nascent Peptidoglycan, and Cross-linking of the Cell Wall by the Essential Penicillin-Binding Protein 2x of Streptococcus pneumoniae
N Bernardo-García, KV Mahasenan, MT Batuecas, M Lee, D Hesek, ...
ACS Chemical Biology 13 (3), 694-702, 2018
322018
Activation by Allostery in Cell-Wall Remodeling by a Modular Membrane-Bound Lytic Transglycosylase from Pseudomonas aeruginosa
T Domínguez-Gil, M Lee, I Acebrón-Avalos, KV Mahasenan, D Hesek, ...
Structure 24 (10), 1729-1741, 2016
322016
The system can't perform the operation now. Try again later.
Articles 1–20