| C2c2 is a single-component programmable RNA-guided RNA-targeting CRISPR effector OO Abudayyeh, JS Gootenberg, S Konermann, J Joung, IM Slaymaker, ... Science 353 (6299), aaf5573, 2016 | 2096 | 2016 |
| Evolutionary classification of CRISPR–Cas systems: a burst of class 2 and derived variants KS Makarova, YI Wolf, J Iranzo, SA Shmakov, OS Alkhnbashi, SJJ Brouns, ... Nature Reviews Microbiology 18 (2), 67-83, 2020 | 1747 | 2020 |
| Discovery and functional characterization of diverse class 2 CRISPR-Cas systems S Shmakov, OO Abudayyeh, KS Makarova, YI Wolf, JS Gootenberg, ... Molecular cell 60 (3), 385-397, 2015 | 1321 | 2015 |
| Diversity and evolution of class 2 CRISPR–Cas systems S Shmakov, A Smargon, D Scott, D Cox, N Pyzocha, W Yan, ... Nature reviews microbiology 15 (3), 169-182, 2017 | 1031 | 2017 |
| Cas13b is a type VI-B CRISPR-associated RNA-guided RNase differentially regulated by accessory proteins Csx27 and Csx28 AA Smargon, DBT Cox, NK Pyzocha, K Zheng, IM Slaymaker, ... Molecular cell 65 (4), 618-630. e7, 2017 | 568 | 2017 |
| Recruitment of CRISPR-Cas systems by Tn7-like transposons JE Peters, KS Makarova, S Shmakov, EV Koonin Proceedings of the National Academy of Sciences 114 (35), E7358-E7366, 2017 | 256 | 2017 |
| CRISPR–Cas in mobile genetic elements: counter-defence and beyond G Faure, SA Shmakov, WX Yan, DR Cheng, DA Scott, JE Peters, ... Nature Reviews Microbiology 17 (8), 513-525, 2019 | 224 | 2019 |
| The CRISPR spacer space is dominated by sequences from species-specific mobilomes SA Shmakov, V Sitnik, KS Makarova, YI Wolf, KV Severinov, EV Koonin MBio 8 (5), 10.1128/mbio. 01397-17, 2017 | 187 | 2017 |
| Systematic prediction of genes functionally linked to CRISPR-Cas systems by gene neighborhood analysis SA Shmakov, KS Makarova, YI Wolf, KV Severinov, EV Koonin Proceedings of the National Academy of Sciences 115 (23), E5307-E5316, 2018 | 148 | 2018 |
| Thousands of previously unknown phages discovered in whole-community human gut metagenomes S Benler, N Yutin, D Antipov, M Rayko, S Shmakov, AB Gussow, ... Microbiome 9, 1-17, 2021 | 123 | 2021 |
| Analysis of metagenome-assembled viral genomes from the human gut reveals diverse putative CrAss-like phages with unique genomic features N Yutin, S Benler, SA Shmakov, YI Wolf, I Tolstoy, M Rayko, D Antipov, ... Nature communications 12 (1), 1044, 2021 | 96 | 2021 |
| Pervasive generation of oppositely oriented spacers during CRISPR adaptation S Shmakov, E Savitskaya, E Semenova, MD Logacheva, KA Datsenko, ... Nucleic acids research 42 (9), 5907-5916, 2014 | 84 | 2014 |
| Machine-learning approach expands the repertoire of anti-CRISPR protein families AB Gussow, AE Park, AL Borges, SA Shmakov, KS Makarova, YI Wolf, ... Nature communications 11 (1), 3784, 2020 | 77 | 2020 |
| Toxin-antitoxin RNA pairs safeguard CRISPR-Cas systems M Li, L Gong, F Cheng, H Yu, D Zhao, R Wang, T Wang, S Zhang, J Zhou, ... Science 372 (6541), eabe5601, 2021 | 74 | 2021 |
| Metagenomic analysis of bacterial communities of Antarctic surface snow A Lopatina, S Medvedeva, S Shmakov, MD Logacheva, V Krylenkov, ... Frontiers in Microbiology 7, 398, 2016 | 70 | 2016 |
| Phylogenomics of Cas4 family nucleases S Hudaiberdiev, S Shmakov, YI Wolf, MP Terns, KS Makarova, EV Koonin BMC evolutionary biology 17, 1-14, 2017 | 68 | 2017 |
| On the origin of reverse transcriptase-using CRISPR-Cas systems and their hyperdiverse, enigmatic spacer repertoires S Silas, KS Makarova, S Shmakov, D Páez-Espino, G Mohr, Y Liu, ... MBio 8 (4), 10.1128/mbio. 00897-17, 2017 | 65 | 2017 |
| CRISPR enzymes and systems K Severinov, F Zhang, YI Wolf, S Shmakov, E Semenova, L Minakhin, ... US Patent 11,060,115, 2021 | 51 | 2021 |
| Altered stoichiometry Escherichia coli Cascade complexes with shortened CRISPR RNA spacers are capable of interference and primed adaptation K Kuznedelov, V Mekler, S Lemak, M Tokmina-Lukaszewska, ... Nucleic acids research, gkw914, 2016 | 51 | 2016 |
| CRISPRidentify: identification of CRISPR arrays using machine learning approach A Mitrofanov, OS Alkhnbashi, SA Shmakov, KS Makarova, EV Koonin, ... Nucleic acids research 49 (4), e20-e20, 2021 | 49 | 2021 |
