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Sara Colombetti
Sara Colombetti
Roche Innovation Center Zurich-pRED
Bestätigte E-Mail-Adresse bei roche.com
Titel
Zitiert von
Zitiert von
Jahr
Prolonged TCR/CD28 engagement drives IL-2-independent T cell clonal expansion through signaling mediated by the mammalian target of rapamycin
S Colombetti, V Basso, DL Mueller, A Mondino
The Journal of Immunology 176 (5), 2730-2738, 2006
9202006
Extracellular HMGB1, a signal of tissue damage, induces mesoangioblast migration and proliferation
R Palumbo, M Sampaolesi, F De Marchis, R Tonlorenzi, S Colombetti, ...
The Journal of cell biology 164 (3), 441-449, 2004
6192004
A novel carcinoembryonic antigen T-cell bispecific antibody (CEA TCB) for the treatment of solid tumors
M Bacac, T Fauti, J Sam, S Colombetti, T Weinzierl, D Ouaret, W Bodmer, ...
Clinical Cancer Research 22 (13), 3286-3297, 2016
3382016
Dendritic cells dictate responses to PD-L1 blockade cancer immunotherapy
M Mayoux, A Roller, V Pulko, S Sammicheli, S Chen, E Sum, C Jost, ...
Science translational medicine 12 (534), eaav7431, 2020
2892020
Tumor-targeted 4-1BB agonists for combination with T cell bispecific antibodies as off-the-shelf therapy
C Claus, C Ferrara, W Xu, J Sam, S Lang, F Uhlenbrock, R Albrecht, ...
Science translational medicine 11 (496), eaav5989, 2019
2092019
CD20-TCB with obinutuzumab pretreatment as next-generation treatment of hematologic malignancies
M Bacac, S Colombetti, S Herter, J Sam, M Perro, S Chen, R Bianchi, ...
Clinical Cancer Research 24 (19), 4785-4797, 2018
1782018
PD-1-cis IL-2R agonism yields better effectors from stem-like CD8+ T cells
L Codarri Deak, V Nicolini, M Hashimoto, M Karagianni, PC Schwalie, ...
Nature 610 (7930), 161-172, 2022
1002022
IL-7 adjuvant treatment enhances long-term tumor antigen-specific CD8+ T-cell responses after immunization with recombinant lentivector
S Colombetti, F Lévy, L Chapatte
Blood, The Journal of the American Society of Hematology 113 (26), 6629-6637, 2009
842009
Clonal anergy is maintained independently of T cell proliferation
S Colombetti, F Benigni, V Basso, A Mondino
The Journal of Immunology 169 (11), 6178-6186, 2002
732002
In Vivo Fluorescence Imaging of the Activity of CEA TCB, a Novel T-Cell Bispecific Antibody, Reveals Highly Specific Tumor Targeting and Fast Induction of T-Cell …
S Lehmann, R Perera, HP Grimm, J Sam, S Colombetti, T Fauti, L Fahrni, ...
Clinical Cancer Research 22 (17), 4417-4427, 2016
672016
Simlukafusp alfa (FAP-IL2v) immunocytokine is a versatile combination partner for cancer immunotherapy
I Waldhauer, V Gonzalez-Nicolini, A Freimoser-Grundschober, TK Nayak, ...
MAbs 13 (1), 1913791, 2021
612021
Xotx5b, a new member of the Otx gene family, may be involved in anterior and eye development in Xenopus laevis
R Vignali, S Colombetti, G Lupo, W Zhang, S Stachel, RM Harland, ...
Mechanisms of development 96 (1), 3-13, 2000
582000
Efficient Induction of Tumor Antigen–Specific CD8+ Memory T Cells by Recombinant Lentivectors
L Chapatte, S Colombetti, JC Cerottini, F Lévy
Cancer research 66 (2), 1155-1160, 2006
552006
Combination of T-cell bispecific antibodies with PD-L1 checkpoint inhibition elicits superior anti-tumor activity
J Sam, S Colombetti, T Fauti, A Roller, M Biehl, L Fahrni, V Nicolini, ...
Frontiers in Oncology 10, 575737, 2020
392020
Application of a MABEL approach for a T-cell-bispecific monoclonal antibody: CEA TCB
S Dudal, H Hinton, AM Giusti, M Bacac, M Muller, T Fauti, S Colombetti, ...
Journal of Immunotherapy 39 (7), 279-289, 2016
322016
Lentivector immunization induces tumor antigen‐specific B and T cell responses in vivo
J Garcia Casado, J Janda, J Wei, L Chapatte, S Colombetti, P Alves, ...
European journal of immunology 38 (7), 1867-1876, 2008
282008
Cross-linking of T cell to B cell lymphoma by the T cell bispecific antibody CD20-TCB induces IFNγ/CXCL10-dependent peripheral T cell recruitment in humanized murine model
F Cremasco, E Menietti, D Speziale, J Sam, S Sammicheli, M Richard, ...
PLoS One 16 (1), e0241091, 2021
272021
CD20 Tcb (RG6026), a novel" 2: 1" T cell bispecific antibody for the treatment of B cell malignancies
M Bacac, P Umaña, S Herter, S Colombetti, J Sam, M Le Clech, ...
Blood 128 (22), 1836, 2016
272016
Rapamycin‐sensitive signals control TCR/CD28‐driven Ifng, Il4 and Foxp3 transcription and promoter region methylation
R Tomasoni, V Basso, K Pilipow, G Sitia, S Saccani, A Agresti, F Mietton, ...
European journal of immunology 41 (7), 2086-2096, 2011
272011
Breast cancer suppressor candidate‐1 (BCSC‐1) is a melanoma tumor suppressor that down regulates MITF
SI Anghel, R Correa‐Rochal, E Budinska, KF Boliganl, S Abraham, ...
Pigment cell & melanoma research 25 (4), 482-487, 2012
242012
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