James M Heather
James M Heather
Massachusetts General Hospital
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Cited by
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The sequence of sequencers: The history of sequencing DNA
JM Heather, B Chain
Genomics 107 (1), 1-8, 2016
Decombinator: a tool for fast, efficient gene assignment in T-cell receptor sequences using a finite state machine
N Thomas, J Heather, W Ndifon, J Shawe-Taylor, B Chain
Bioinformatics 29 (5), 542-550, 2013
High-throughput sequencing of the T-cell receptor repertoire: pitfalls and opportunities
JM Heather, M Ismail, T Oakes, B Chain
Briefings in Bioinformatics, bbw138, 2017
Computational analysis of stochastic heterogeneity in PCR amplification efficiency revealed by single molecule barcoding
K Best, T Oakes, JM Heather, J Shawe-Taylor, B Chain
Scientific reports 5, 2015
Quantitative characterisation of the T cell receptor repertoire of na´ve and memory subsets using an integrated experimental and computational pipeline which is robustá…
T Oakes, JM Heather, K Best, R Byng-Maddick, C Husovsky, M Ismail, ...
Frontiers in Immunology 8, 1267, 2017
Dynamic Perturbations of the T-Cell Receptor Repertoire in Chronic HIV Infection and following Antiretroviral Therapy
JM Heather, K Best, T Oakes, ER Gray, JK Roe, N Thomas, N Friedman, ...
Frontiers in Immunology 6, 2015
Extranuclear DNA accumulates in aged cells and contributes to senescence and inflammation
YY Lan, JM Heather, T Eisenhaure, CS Garris, D Lieb, R Raychowdhury, ...
Aging cell 18 (2), e12901, 2019
Feature selection using a one dimensional na´ve Bayes' classifier increases the accuracy of support vector machine classification of CDR3 repertoires.
M Cinelli, Y Sun, K Best, JM Heather, S Reich-Zeliger, E Shifrut, ...
Bioinformatics (Oxford, England) 33 (7), 951, 2017
Epigenetic control of viral life-cycle by a DNA-methylation dependent transcription factor
K Flower, D Thomas, J Heather, S Ramasubramanyan, S Jones, ...
PLoS One 6 (10), e25922, 2011
The naive T-cell receptor repertoire has an extremely broad distribution of clone sizes
PC de Greef, T Oakes, B Gerritsen, M Ismail, JM Heather, R Hermsen, ...
Elife 9, e49900, 2020
The Epstein–Barr virus lytic cycle activator Zta interacts with methylated ZRE in the promoter of host target gene egr1
J Heather, K Flower, S Isaac, AJ Sinclair
Journal of General Virology 90 (6), 1450-1454, 2009
Specificity, privacy and degeneracy in the CD4 T cell receptor repertoire following immunisation.
Y Sun, K Best, M Cinelli, S Reich-Zeliger, E Shifrut, N Friedman, ...
Frontiers in Immunology 8, 430, 2017
Antibody-mediated delivery of viral epitopes to tumors harnesses CMV-specific T cells for cancer therapy
DG Millar, RR Ramjiawan, K Kawaguchi, N Gupta, J Chen, S Zhang, ...
Nature Biotechnology 38 (4), 420-425, 2020
Clinical T Cell Receptor Repertoire Deep Sequencing and Analysis: An Application to Monitor Immune Reconstitution Following Cord Blood Transplantation
AS Gkazi, BK Margetts, T Attenborough, L Mhaldien, JF Standing, ...
Frontiers in Immunology 9, 2018
Massively parallel interrogation and mining of natively paired human TCRαβ repertoires
MJ Spindler, AL Nelson, EK Wagner, N Oppermans, JS Bridgeman, ...
Nature Biotechnology 38 (5), 609-619, 2020
Validation of Immune Cell Modules in Multicellular Transcriptomic Data.
G Pollara, MJ Murray, JM Heather, R Byng-Maddick, N Guppy, M Ellis, ...
PloS one 12 (1), e0169271, 2017
Immune dysregulation in immunodeficiency disorders: The role of T-cell receptor sequencing
GK Wong, JM Heather, S Barmettler, M Cobbold
Journal of Autoimmunity, 2017
Accelerated Loss of TCR Repertoire Diversity in Common Variable Immunodeficiency
GK Wong, D Millar, S Penny, JM Heather, P Mistry, N Buettner, J Bryon, ...
The Journal of Immunology 197 (5), 1642-1649, 2016
The T cell response to the contact sensitizer Paraphenylenediamine is characterized by a Polyclonal Diverse repertoire of antigen-specific receptors
T Oakes, AL Popple, J Williams, K Best, JM Heather, M Ismail, G Maxwell, ...
Frontiers in immunology 8, 162, 2017
An Economical, Quantitative, and Robust Protocol for High-Throughput T Cell Receptor Sequencing from Tumor or Blood
I Uddin, K Joshi, T Oakes, JM Heather, C Swanton, B Chain
Cancer Immunosurveillance, 15-42, 2019
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