| Parkinson's disease patient-derived induced pluripotent stem cells free of viral reprogramming factors F Soldner, D Hockemeyer, C Beard, Q Gao, GW Bell, EG Cook, G Hargus, ... Cell 136 (5), 964-977, 2009 | 1961 | 2009 |
| Differentiated Parkinson patient-derived induced pluripotent stem cells grow in the adult rodent brain and reduce motor asymmetry in Parkinsonian rats G Hargus, O Cooper, M Deleidi, A Levy, K Lee, E Marlow, A Yow, ... Proceedings of the National Academy of Sciences 107 (36), 15921-15926, 2010 | 592 | 2010 |
| Pharmacological rescue of mitochondrial deficits in iPSC-derived neural cells from patients with familial Parkinson’s disease O Cooper, H Seo, S Andrabi, C Guardia-Laguarta, J Graziotto, ... Science translational medicine 4 (141), 141ra90-141ra90, 2012 | 557 | 2012 |
| Cell type analysis of functional fetal dopamine cell suspension transplants in the striatum and substantia nigra of patients with Parkinson's disease I Mendez, R Sanchez-Pernaute, O Cooper, A Viñuela, D Ferrari, ... Brain 128 (7), 1498-1510, 2005 | 504 | 2005 |
| Successful function of autologous iPSC-derived dopamine neurons following transplantation in a non-human primate model of Parkinson’s disease PJ Hallett, M Deleidi, A Astradsson, GA Smith, O Cooper, TM Osborn, ... Cell stem cell 16 (3), 269-274, 2015 | 377 | 2015 |
| LRRK2 mutations cause mitochondrial DNA damage in iPSC-derived neural cells from Parkinson's disease patients: reversal by gene correction LH Sanders, J Laganière, O Cooper, SK Mak, BJ Vu, YA Huang, ... Neurobiology of disease 62, 381-386, 2014 | 285 | 2014 |
| Differentiation of human ES and Parkinson's disease iPS cells into ventral midbrain dopaminergic neurons requires a high activity form of SHH, FGF8a and specific … O Cooper, G Hargus, M Deleidi, A Blak, T Osborn, E Marlow, K Lee, ... Molecular and Cellular Neuroscience 45 (3), 258-266, 2010 | 262 | 2010 |
| Improved cell therapy protocols for Parkinson's disease based on differentiation efficiency and safety of hESC-, hiPSC-, and non-human primate iPSC-derived dopaminergic neurons M Sundberg, H Bogetofte, T Lawson, J Jansson, G Smith, A Astradsson, ... Stem cells 31 (8), 1548-1562, 2013 | 260 | 2013 |
| Selective COX-2 inhibition prevents progressive dopamine neuron degeneration in a rat model of Parkinson's disease R Sánchez-Pernaute, A Ferree, O Cooper, M Yu, AL Brownell, O Isacson Journal of neuroinflammation 1, 1-11, 2004 | 244 | 2004 |
| Intrastriatal transforming growth factor α delivery to a model of Parkinson's disease induces proliferation and migration of endogenous adult neural progenitor cells without … O Cooper, O Isacson Journal of Neuroscience 24 (41), 8924-8931, 2004 | 196 | 2004 |
| Long-term health of dopaminergic neuron transplants in Parkinson's disease patients PJ Hallett, O Cooper, D Sadi, H Robertson, I Mendez, O Isacson Cell reports 7 (6), 1755-1761, 2014 | 173 | 2014 |
| The migration of paraxial and lateral plate mesoderm cells emerging from the late primitive streak is controlled by different Wnt signals D Sweetman, L Wagstaff, O Cooper, C Weijer, A Münsterberg BMC developmental biology 8, 1-15, 2008 | 83 | 2008 |
| Fate mapping and lineage analyses demonstrate the production of a large number of striatal neuroblasts after transforming growth factor α and noggin striatal infusions into the … A De Chevigny, O Cooper, A Vinuela, C Reske-Nielsen, DC Lagace, ... Stem cells 26 (9), 2349-2360, 2008 | 67 | 2008 |
| Transcript expression levels of full-length alpha-synuclein and its three alternatively spliced variants in Parkinson's disease brain regions and in a transgenic mouse model of … JR McLean, PJ Hallett, O Cooper, M Stanley, O Isacson Molecular and Cellular Neuroscience 49 (2), 230-239, 2012 | 63 | 2012 |
| Recent advances in cell-based therapy for Parkinson disease A Astradsson, O Cooper, A Vinuela, O Isacson Neurosurgical Focus 24 (3-4), E6, 2008 | 55 | 2008 |
| Lack of functional relevance of isolated cell damage in transplants of Parkinson’s disease patients O Cooper, A Astradsson, P Hallett, H Robertson, I Mendez, O Isacson Journal of neurology 256, 310-316, 2009 | 53 | 2009 |
| Oct4-induced reprogramming is required for adult brain neural stem cell differentiation into midbrain dopaminergic neurons M Deleidi, O Cooper, G Hargus, A Levy, O Isacson PloS one 6 (5), e19926, 2011 | 52 | 2011 |
| Context-dependent neuronal differentiation and germ layer induction of Smad4−/− and Cripto−/− embryonic stem cells KC Sonntag, R Simantov, L Björklund, O Cooper, J Pruszak, F Kowalke, ... Molecular and Cellular Neuroscience 28 (3), 417-429, 2005 | 48 | 2005 |
| Neuroblast protuberances in the subventricular zone of the regenerative MRL/MpJ mouse KL Baker, SB Daniels, JB Lennington, T Lardaro, A Czap, RQ Notti, ... Journal of Comparative Neurology 498 (6), 747-761, 2006 | 45 | 2006 |
| Klhl31 is associated with skeletal myogenesis and its expression is regulated by myogenic signals and Myf-5 A Abou-Elhamd, O Cooper, A Münsterberg Mechanisms of Development 126 (10), 852-862, 2009 | 24 | 2009 |
