Costin Leu
Costin Leu
Research staff at the Cleveland Clinic
Verified email at
Cited by
Cited by
Analysis of shared heritability in common disorders of the brain
Brainstorm Consortium, V Anttila, B Bulik-Sullivan, HK Finucane, ...
Science 360 (6395), eaap8757, 2018
15q13. 3 microdeletions increase risk of idiopathic generalized epilepsy
I Helbig, HC Mefford, AJ Sharp, M Guipponi, M Fichera, A Franke, ...
Nature genetics 41 (2), 160-162, 2009
Recurrent microdeletions at 15q11. 2 and 16p13. 11 predispose to idiopathic generalized epilepsies
CGF de Kovel, H Trucks, I Helbig, HC Mefford, C Baker, C Leu, C Kluck, ...
Brain 133 (1), 23-32, 2010
Familial and sporadic 15q13. 3 microdeletions in idiopathic generalized epilepsy: precedent for disorders with complex inheritance
LM Dibbens, S Mullen, I Helbig, HC Mefford, MA Bayly, S Bellows, C Leu, ...
Human molecular genetics 18 (19), 3626-3631, 2009
Epilepsy, hippocampal sclerosis and febrile seizures linked by common genetic variation around SCN1A
D Kasperavičiūtė, CB Catarino, M Matarin, C Leu, J Novy, A Tostevin, ...
Brain 136 (10), 3140-3150, 2013
Ultra-rare genetic variation in the epilepsies: a whole-exome sequencing study of 17,606 individuals
YCA Feng, DP Howrigan, LE Abbott, K Tashman, F Cerrato, T Singh, ...
The American Journal of Human Genetics 105 (2), 267-282, 2019
Genetic determinants of common epilepsies: a meta-analysis of genome-wide association studies
TILAE Consortium
The Lancet. Neurology 13 (9), 893, 2014
Genome-wide mega-analysis identifies 16 loci and highlights diverse biological mechanisms in the common epilepsies
Nature communications 9 (1), 5269, 2018
Genome-wide association analysis of genetic generalized epilepsies implicates susceptibility loci at 1q43, 2p16. 1, 2q22. 3 and 17q21. 32
Epicure Consortium, EMINet Consortium, M Steffens, C Leu, AK Ruppert, ...
Human molecular genetics 21 (24), 5359-5372, 2012
CHD2 variants are a risk factor for photosensitivity in epilepsy
EC Galizia, CT Myers, C Leu, CGF De Kovel, T Afrikanova, ...
Brain 138 (5), 1198-1208, 2015
GLUT1 mutations are a rare cause of familial idiopathic generalized epilepsy
P Striano, YG Weber, MR Toliat, J Schubert, C Leu, R Chaimana, ...
Neurology 78 (8), 557-562, 2012
Pitfalls in genetic testing: the story of missed SCN1A mutations
T Djémié, S Weckhuysen, S von Spiczak, GL Carvill, J Jaehn, ...
Molecular genetics & genomic medicine 4 (4), 457-464, 2016
Dysfunction of NaV1. 4, a skeletal muscle voltage-gated sodium channel, in sudden infant death syndrome: a case-control study
R Männikkö, L Wong, DJ Tester, MG Thor, R Sud, DM Kullmann, ...
The Lancet 391 (10129), 1483-1492, 2018
Rare coding variants in genes encoding GABAA receptors in genetic generalised epilepsies: an exome-based case-control study
P May, S Girard, M Harrer, DR Bobbili, J Schubert, S Wolking, F Becker, ...
The Lancet Neurology 17 (8), 699-708, 2018
Carbamazepine‐and oxcarbazepine‐induced hyponatremia in people with epilepsy
B Berghuis, J van der Palen, GJ de Haan, D Lindhout, BPC Koeleman, ...
Epilepsia 58 (7), 1227-1233, 2017
Rare exonic deletions of the RBFOX1 gene increase risk of idiopathic generalized epilepsy
D Lal, H Trucks, RS Mřller, H Hjalgrim, BPC Koeleman, CGF de Kovel, ...
Epilepsia 54 (2), 265-271, 2013
Exon‐disrupting deletions of NRXN1 in idiopathic generalized epilepsy
RS Mřller, YG Weber, LL Klitten, H Trucks, H Muhle, WS Kunz, ...
Epilepsia 54 (2), 256-264, 2013
Polygenic burden in focal and generalized epilepsies
C Leu, R Stevelink, AW Smith, SB Goleva, M Kanai, L Ferguson, ...
Brain 142 (11), 3473-3481, 2019
Predicting functional effects of missense variants in voltage-gated sodium and calcium channels
HO Heyne, D Baez-Nieto, S Iqbal, DS Palmer, A Brunklaus, P May, ...
Science translational medicine 12 (556), eaay6848, 2020
Genome-wide polygenic burden of rare deleterious variants in sudden unexpected death in epilepsy
C Leu, S Balestrini, B Maher, L Hernández-Hernández, P Gormley, ...
EBioMedicine 2 (9), 1063-1070, 2015
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