SeqNLS: nuclear localization signal prediction based on frequent pattern mining and linear motif scoring J Lin, J Hu PloS one 8 (10), e76864, 2013 | 133 | 2013 |
Genetic contributors to risk of schizophrenia in the presence of a 22q11. 2 deletion I Cleynen, W Engchuan, MS Hestand, T Heung, AM Holleman, ... Molecular psychiatry 26 (8), 4496-4510, 2021 | 110 | 2021 |
HEDD: human enhancer disease database Z Wang, Q Zhang, W Zhang, JR Lin, Y Cai, J Mitra, ZD Zhang Nucleic acids research 46 (D1), D113-D120, 2018 | 54 | 2018 |
Integrated post-GWAS analysis sheds new light on the disease mechanisms of schizophrenia JR Lin, Y Cai, Q Zhang, W Zhang, R Nogales-Cadenas, ZD Zhang Genetics 204 (4), 1587-1600, 2016 | 48 | 2016 |
Genetics of extreme human longevity to guide drug discovery for healthy ageing ZD Zhang, S Milman, JR Lin, S Wierbowski, H Yu, N Barzilai, ... Nature metabolism 2 (8), 663-672, 2020 | 47 | 2020 |
Minimalist ensemble algorithms for genome-wide protein localization prediction JR Lin, AM Mondal, R Liu, J Hu BMC bioinformatics 13, 1-12, 2012 | 42 | 2012 |
Systems-level analysis of human aging genes shed new light on mechanisms of aging Q Zhang, R Nogales-Cadenas, JR Lin, W Zhang, Y Cai, J Vijg, ZD Zhang Human molecular genetics 25 (14), 2934-2947, 2016 | 40 | 2016 |
Transcriptomic dynamics of breast cancer progression in the MMTV-PyMT mouse model Y Cai, R Nogales-Cadenas, Q Zhang, JR Lin, W Zhang, K O’Brien, ... Bmc Genomics 18, 1-14, 2017 | 38 | 2017 |
Rare genetic coding variants associated with human longevity and protection against age-related diseases JR Lin, P Sin-Chan, V Napolioni, GG Torres, J Mitra, Q Zhang, ... Nature Aging 1 (9), 783-794, 2021 | 28 | 2021 |
Deep post-GWAS analysis identifies potential risk genes and risk variants for Alzheimer’s disease, providing new insights into its disease mechanisms Z Wang, Q Zhang, JR Lin, MR Jabalameli, J Mitra, N Nguyen, ZD Zhang Scientific reports 11 (1), 20511, 2021 | 24 | 2021 |
MicroRNA expression and gene regulation drive breast cancer progression and metastasis in PyMT mice R Nogales-Cadenas, Y Cai, JR Lin, Q Zhang, W Zhang, C Montagna, ... Breast Cancer Research 18, 1-13, 2016 | 20 | 2016 |
Epigenetic alterations to Polycomb targets precede malignant transition in a mouse model of breast cancer Y Cai, JR Lin, Q Zhang, K O’Brien, C Montagna, ZD Zhang Scientific reports 8 (1), 5535, 2018 | 14 | 2018 |
Integrated rare variant-based risk gene prioritization in disease case-control sequencing studies JR Lin, Q Zhang, Y Cai, BE Morrow, ZD Zhang PLoS genetics 13 (12), e1007142, 2017 | 11 | 2017 |
Network based subcellular localization prediction for multi-label proteins AM Mondal, J Lin, J Hu 2011 IEEE international conference on bioinformatics and biomedicine …, 2011 | 11 | 2011 |
PGA: post-GWAS analysis for disease gene identification JR Lin, D Jaroslawicz, Y Cai, Q Zhang, Z Wang, ZD Zhang Bioinformatics 34 (10), 1786-1788, 2018 | 9 | 2018 |
Genomic expansion of Aldh1a1 protects beavers against high metabolic aldehydes from lipid oxidation Q Zhang, G Tombline, J Ablaeva, L Zhang, X Zhou, Z Smith, Y Zhao, ... Cell reports 37 (6), 2021 | 7 | 2021 |
From Gene Expression to Disease Phenotypes: Network-Based Approaches to Study Complex Human Diseases Q Zhang, W Zhang, R Nogales-Cadenas, JR Lin, Y Cai, Z ZD Transcriptomics and Gene Regulation, 115-140, 2015 | 3 | 2015 |
Computational identification of post‐translational modification‐based nuclear import regulations by characterizing nuclear localization signal‐import receptor interaction JR Lin, Z Liu, J Hu Proteins: Structure, Function, and Bioinformatics 82 (10), 2783-2796, 2014 | 3 | 2014 |
Chromatin regulators in the TBX1 network confer risk for conotruncal heart defects in 22q11. 2DS Y Zhao, Y Wang, L Shi, DM McDonald-McGinn, TB Crowley, DE McGinn, ... NPJ genomic medicine 8 (1), 17, 2023 | 2 | 2023 |
Deep Post-GWAS Analysis Identifies Potential Risk Genes and Causal Variants for Alzheimer’s Disease, Providing New Insights Into Its Disease Mechanisms Z Wang, Q Zhang, JR Lin, MR Jabalamel, J Mitra, N Nguyen, Z Zhang | 2 | 2020 |