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Hanwen Zhang
Hanwen Zhang
Verified email at northshore.org
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Year
Open chromatin profiling in hiPSC-derived neurons prioritizes functional noncoding psychiatric risk variants and highlights neurodevelopmental loci
MP Forrest, H Zhang, W Moy, H McGowan, C Leites, LE Dionisio, Z Xu, ...
Cell stem cell 21 (3), 305-318. e8, 2017
1182017
Allele-specific open chromatin in human iPSC neurons elucidates functional disease variants
S Zhang, H Zhang, Y Zhou, M Qiao, S Zhao, A Kozlova, J Shi, AR Sanders, ...
Science 369 (6503), 561-565, 2020
832020
Deconvolution of transcriptional networks identifies TCF4 as a master regulator in schizophrenia
A Doostparast Torshizi, C Armoskus, H Zhang, MP Forrest, S Zhang, ...
Science advances 5 (9), eaau4139, 2019
552019
ASCL1-and DLX2-induced GABAergic neurons from hiPSC-derived NPCs
N Barretto, H Zhang, SK Powell, MB Fernando, S Zhang, EK Flaherty, ...
Journal of neuroscience methods 334, 108548, 2020
382020
Publicly available hiPSC lines with extreme polygenic risk scores for modeling schizophrenia
K Dobrindt, H Zhang, D Das, S Abdollahi, T Prorok, S Ghosh, S Weintraub, ...
Complex psychiatry 6 (3-4), 68-82, 2021
232021
Open chromatin dynamics reveals stage-specific transcriptional networks in hiPSC-based neurodevelopmental model
S Zhang, W Moy, H Zhang, C Leites, H McGowan, J Shi, AR Sanders, ...
Stem cell research 29, 88-98, 2018
202018
Cell Type-Specific and Cross-Population Polygenic Risk Score Analyses of MIR137 Gene Pathway in Schizophrenia
Y Yao, W Guo, S Zhang, H Yu, H Yan, H Zhang, AR Sanders, W Yue, ...
MIR137, 0
15*
The Genetic Relevance of Human Induced Pluripotent Stem Cell-Derived Microglia to Alzheimer’s Disease and Major Neuropsychiatric Disorders
RR Butler III, A Kozlova, H Zhang, S Zhang, M Streit, AR Sanders, ...
Molecular neuropsychiatry 5 (1), 85-96, 2019
112019
Loss of function of OTUD7A in the schizophrenia-associated 15q13. 3 deletion impairs synapse development and function in human neurons
A Kozlova, S Zhang, AV Kotlar, B Jamison, H Zhang, S Shi, MP Forrest, ...
The American Journal of Human Genetics 109 (8), 1500-1519, 2022
82022
Multiple genes in a single GWAS risk locus synergistically mediate aberrant synaptic development and function in human neurons
S Zhang, H Zhang, MP Forrest, Y Zhou, X Sun, VA Bagchi, A Kozlova, ...
Cell Genomics 3 (9), 2023
52023
Sex-specific nicotine sensitization and imprinting of self-administration in rats inform GWAS findings on human addiction phenotypes
A Kozlova, RR Butler III, S Zhang, T Ujas, H Zhang, S Steidl, AR Sanders, ...
Neuropsychopharmacology 46 (10), 1746-1756, 2021
52021
Multiple genes in cis mediate the effects of a single chromatin accessibility variant on aberrant synaptic development and function in human neurons
S Zhang, H Zhang, MP Forrest, Y Zhou, VA Bagchi, A Kozlova, ...
bioRxiv, 2021.12. 11.472229, 2021
42021
46 MODELLING THE SCHIZOPHRENIA-ASSOCIATED LOSS-OF-FUNCTION MUTATION OF SETD1A IN HUMAN STEM CELL-DERIVED BRAIN ORGANOIDS
S West, H Zhang, S Zhang, A Kozlova, A Sanders, Z Pang, P Gejman, ...
European Neuropsychopharmacology 29, S84-S85, 2019
22019
Predicting Epigenomic Functions of Genetic Variants in the Context of Neurodevelopment via Deep Transfer Learning
B Lai, S Qian, H Zhang, S Zhang, A Kozlova, J Duan, J Xu, X He
bioRxiv, 2021
12021
Landscape of allele-specific open chromatin in human ipsc-differentiated neurons and it implication for mental disorders
S Zhang, W Moy, H Zhang, H McGowan, J Shi, C Leites, Z Pang, ...
European Neuropsychopharmacology 29, S799-S800, 2019
12019
Reverse engineering of transcriptional networks uncovers candidate master regulators governing neuropathology of schizophrenia
AD Torshizi, C Armoskus, S Zhang, H Zhang, OV Evgrafov, JA Knowles, ...
bioRxiv, 133363, 2017
12017
20. CHROMATIN ACCESSIBILITY MAPPING REVEALS COMPOUND GENETIC EFFECTS AT A SCHIZOPHRENIA GWAS RISK LOCUS IMPAIRING NEURODEVELOPMENT AND SYNAPTIC FUNCTION IN HUMAN NEURONS
S Zhang, H Zhang, M Forrest, Y Zhou, V Bagchi, A Kozlova, M Dos Santos, ...
European Neuropsychopharmacology 51, e50-e51, 2021
2021
57. MODELING THE LOSS-OF-FUNCTION MUTATION OF OTUD7A WITHIN THE SCHIZOPHRENIA-ASSOCIATED 15Q13. 3 MICRODELETION IN HUMAN NEURONS
A Kozlova, S Zhang, A Kotlar, J McDaid, MP Forrest, H Zhang, B Jamison, ...
European Neuropsychopharmacology 51, e71, 2021
2021
Transcriptomic signatures of sex-specific nicotine sensitization and imprinting of self-administration in rats inform GWAS findings on human addiction phenotypes
A Kozlova, RR Butler III, S Zhang, T Ujas, H Zhang, S Steidl, AR Sanders, ...
bioRxiv, 2020.10. 05.327155, 2020
2020
Deconvolution of transcriptional networks identifies TCF4 as a master regulator in schizophrenia
AD Torshizi, C Armoskus, H Zhang, MP Forrest, S Zhang, T Souaiaia, ...
Science advances 5 (9), eaau4139, 2019
2019
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