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Allele-specific open chromatin in human iPSC neurons elucidates functional disease variants S Zhang, H Zhang, Y Zhou, M Qiao, S Zhao, A Kozlova, J Shi, AR Sanders, ... Science 369 (6503), 561-565, 2020 | 83 | 2020 |
Deconvolution of transcriptional networks identifies TCF4 as a master regulator in schizophrenia A Doostparast Torshizi, C Armoskus, H Zhang, MP Forrest, S Zhang, ... Science advances 5 (9), eaau4139, 2019 | 55 | 2019 |
ASCL1-and DLX2-induced GABAergic neurons from hiPSC-derived NPCs N Barretto, H Zhang, SK Powell, MB Fernando, S Zhang, EK Flaherty, ... Journal of neuroscience methods 334, 108548, 2020 | 38 | 2020 |
Publicly available hiPSC lines with extreme polygenic risk scores for modeling schizophrenia K Dobrindt, H Zhang, D Das, S Abdollahi, T Prorok, S Ghosh, S Weintraub, ... Complex psychiatry 6 (3-4), 68-82, 2021 | 23 | 2021 |
Open chromatin dynamics reveals stage-specific transcriptional networks in hiPSC-based neurodevelopmental model S Zhang, W Moy, H Zhang, C Leites, H McGowan, J Shi, AR Sanders, ... Stem cell research 29, 88-98, 2018 | 20 | 2018 |
Cell Type-Specific and Cross-Population Polygenic Risk Score Analyses of MIR137 Gene Pathway in Schizophrenia Y Yao, W Guo, S Zhang, H Yu, H Yan, H Zhang, AR Sanders, W Yue, ... MIR137, 0 | 15* | |
The Genetic Relevance of Human Induced Pluripotent Stem Cell-Derived Microglia to Alzheimer’s Disease and Major Neuropsychiatric Disorders RR Butler III, A Kozlova, H Zhang, S Zhang, M Streit, AR Sanders, ... Molecular neuropsychiatry 5 (1), 85-96, 2019 | 11 | 2019 |
Loss of function of OTUD7A in the schizophrenia-associated 15q13. 3 deletion impairs synapse development and function in human neurons A Kozlova, S Zhang, AV Kotlar, B Jamison, H Zhang, S Shi, MP Forrest, ... The American Journal of Human Genetics 109 (8), 1500-1519, 2022 | 8 | 2022 |
Multiple genes in a single GWAS risk locus synergistically mediate aberrant synaptic development and function in human neurons S Zhang, H Zhang, MP Forrest, Y Zhou, X Sun, VA Bagchi, A Kozlova, ... Cell Genomics 3 (9), 2023 | 5 | 2023 |
Sex-specific nicotine sensitization and imprinting of self-administration in rats inform GWAS findings on human addiction phenotypes A Kozlova, RR Butler III, S Zhang, T Ujas, H Zhang, S Steidl, AR Sanders, ... Neuropsychopharmacology 46 (10), 1746-1756, 2021 | 5 | 2021 |
Multiple genes in cis mediate the effects of a single chromatin accessibility variant on aberrant synaptic development and function in human neurons S Zhang, H Zhang, MP Forrest, Y Zhou, VA Bagchi, A Kozlova, ... bioRxiv, 2021.12. 11.472229, 2021 | 4 | 2021 |
46 MODELLING THE SCHIZOPHRENIA-ASSOCIATED LOSS-OF-FUNCTION MUTATION OF SETD1A IN HUMAN STEM CELL-DERIVED BRAIN ORGANOIDS S West, H Zhang, S Zhang, A Kozlova, A Sanders, Z Pang, P Gejman, ... European Neuropsychopharmacology 29, S84-S85, 2019 | 2 | 2019 |
Predicting Epigenomic Functions of Genetic Variants in the Context of Neurodevelopment via Deep Transfer Learning B Lai, S Qian, H Zhang, S Zhang, A Kozlova, J Duan, J Xu, X He bioRxiv, 2021 | 1 | 2021 |
Landscape of allele-specific open chromatin in human ipsc-differentiated neurons and it implication for mental disorders S Zhang, W Moy, H Zhang, H McGowan, J Shi, C Leites, Z Pang, ... European Neuropsychopharmacology 29, S799-S800, 2019 | 1 | 2019 |
Reverse engineering of transcriptional networks uncovers candidate master regulators governing neuropathology of schizophrenia AD Torshizi, C Armoskus, S Zhang, H Zhang, OV Evgrafov, JA Knowles, ... bioRxiv, 133363, 2017 | 1 | 2017 |
20. CHROMATIN ACCESSIBILITY MAPPING REVEALS COMPOUND GENETIC EFFECTS AT A SCHIZOPHRENIA GWAS RISK LOCUS IMPAIRING NEURODEVELOPMENT AND SYNAPTIC FUNCTION IN HUMAN NEURONS S Zhang, H Zhang, M Forrest, Y Zhou, V Bagchi, A Kozlova, M Dos Santos, ... European Neuropsychopharmacology 51, e50-e51, 2021 | | 2021 |
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Transcriptomic signatures of sex-specific nicotine sensitization and imprinting of self-administration in rats inform GWAS findings on human addiction phenotypes A Kozlova, RR Butler III, S Zhang, T Ujas, H Zhang, S Steidl, AR Sanders, ... bioRxiv, 2020.10. 05.327155, 2020 | | 2020 |
Deconvolution of transcriptional networks identifies TCF4 as a master regulator in schizophrenia AD Torshizi, C Armoskus, H Zhang, MP Forrest, S Zhang, T Souaiaia, ... Science advances 5 (9), eaau4139, 2019 | | 2019 |