Dieter Edbauer
Dieter Edbauer
DZNE Munich
Verified email at - Homepage
Cited by
Cited by
Reconstitution of γ-secretase activity
D Edbauer, E Winkler, JT Regula, B Pesold, H Steiner, C Haass
Nature cell biology 5 (5), 486-488, 2003
The C9orf72 GGGGCC repeat is translated into aggregating dipeptide-repeat proteins in FTLD/ALS
K Mori, SM Weng, T Arzberger, S May, K Rentzsch, E Kremmer, B Schmid, ...
Science 339 (6125), 1335-1338, 2013
Regulation of synaptic structure and function by FMRP-associated microRNAs miR-125b and miR-132
D Edbauer, JR Neilson, KA Foster, CF Wang, DP Seeburg, MN Batterton, ...
Neuron 65 (3), 373-384, 2010
ALS‐associated fused in sarcoma (FUS) mutations disrupt Transportin‐mediated nuclear import
D Dormann, R Rodde, D Edbauer, E Bentmann, I Fischer, A Hruscha, ...
The EMBO journal 29 (16), 2841-2857, 2010
PEN-2 is an integral component of the γ-secretase complex required for coordinated expression of presenilin and nicastrin
H Steiner, E Winkler, D Edbauer, S Prokop, G Basset, A Yamasaki, ...
Journal of Biological Chemistry 277 (42), 39062-39065, 2002
Bidirectional transcripts of the expanded C9orf72 hexanucleotide repeat are translated into aggregating dipeptide repeat proteins
K Mori, T Arzberger, FA Grässer, I Gijselinck, S May, K Rentzsch, ...
Acta neuropathologica 126 (6), 881-893, 2013
Presenilin-dependent intramembrane proteolysis of CD44 leads to the liberation of its intracellular domain and the secretion of an Aβ-like peptide
S Lammich, M Okochi, M Takeda, C Kaether, A Capell, AK Zimmer, ...
Journal of Biological Chemistry 277 (47), 44754-44759, 2002
Gain of Toxicity from ALS/FTD-Linked Repeat Expansions in C9ORF72 Is Alleviated by Antisense Oligonucleotides Targeting GGGGCC-Containing RNAs
J Jiang, Q Zhu, TF Gendron, S Saberi, M McAlonis-Downes, A Seelman, ...
Neuron 90 (3), 535-550, 2016
C9ORF72 repeat expansions in mice cause TDP-43 pathology, neuronal loss, and behavioral deficits
J Chew, TF Gendron, M Prudencio, H Sasaguri, YJ Zhang, ...
Science 348 (6239), 1151-1154, 2015
Presenilin and nicastrin regulate each other and determine amyloid β-peptide production via complex formation
D Edbauer, E Winkler, C Haass, H Steiner
Proceedings of the National Academy of Sciences 99 (13), 8666-8671, 2002
hnRNP A3 binds to GGGGCC repeats and is a constituent of p62-positive/TDP43-negative inclusions in the hippocampus of patients with C9orf72 mutations
K Mori, S Lammich, IRA Mackenzie, I Forné, S Zilow, H Kretzschmar, ...
Acta neuropathologica 125 (3), 413-423, 2013
microRNA‐34c is a novel target to treat dementias
A Zovoilis, HY Agbemenyah, RC Agis‐Balboa, RM Stilling, D Edbauer, ...
The EMBO journal 30 (20), 4299-4308, 2011
Presenilin-1 mutations of leucine 166 equally affect the generation of the Notch and APP intracellular domains independent of their effect on Aβ42 production
T Moehlmann, E Winkler, X Xia, D Edbauer, J Murrell, A Capell, C Kaether, ...
Proceedings of the National Academy of Sciences 99 (12), 8025-8030, 2002
Dipeptide repeat protein pathology in C9ORF72 mutation cases: clinico-pathological correlations
IR Mackenzie, T Arzberger, E Kremmer, D Troost, S Lorenzl, K Mori, ...
Acta neuropathologica 126 (6), 859-879, 2013
MicroRNA-132 dysregulation in schizophrenia has implications for both neurodevelopment and adult brain function
BH Miller, Z Zeier, L Xi, TA Lanz, S Deng, J Strathmann, D Willoughby, ...
Proceedings of the National Academy of Sciences 109 (8), 3125-3130, 2012
Role of Septin cytoskeleton in spine morphogenesis and dendrite development in neurons
T Tada, A Simonetta, M Batterton, M Kinoshita, D Edbauer, M Sheng
Current Biology 17 (20), 1752-1758, 2007
Insulin-degrading enzyme rapidly removes the β-amyloid precursor protein intracellular domain (AICD)
D Edbauer, M Willem, S Lammich, H Steiner, C Haass
Journal of Biological Chemistry 277 (16), 13389-13393, 2002
Sequestration of multiple RNA recognition motif-containing proteins by C9orf72 repeat expansions
J Cooper-Knock, MJ Walsh, A Higginbottom, J Robin Highley, ...
Brain 137 (7), 2040-2051, 2014
Presenilin-1 affects trafficking and processing of βAPP and is targeted in a complex with nicastrin to the plasma membrane
C Kaether, S Lammich, D Edbauer, M Ertl, J Rietdorf, A Capell, H Steiner, ...
The Journal of cell biology 158 (3), 551-561, 2002
C9orf72 FTLD/ALS-associated Gly-Ala dipeptide repeat proteins cause neuronal toxicity and Unc119 sequestration
S May, D Hornburg, MH Schludi, T Arzberger, K Rentzsch, BM Schwenk, ...
Acta neuropathologica 128 (4), 485-503, 2014
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