Paul H Huang
Paul H Huang
Team Leader, Molecular & Systems Oncology, Institute of Cancer Research, London, UK
Verified email at - Homepage
Cited by
Cited by
Quantitative analysis of EGFRvIII cellular signaling networks reveals a combinatorial therapeutic strategy for glioblastoma
PH Huang, A Mukasa, R Bonavia, RA Flynn, ZE Brewer, WK Cavenee, ...
Proceedings of the National Academy of Sciences 104 (31), 12867-12872, 2007
Oncogenic EGFR signaling networks in glioma
PH Huang, AM Xu, FM White
Sci Signal 2 (87), re6, 2009
14-3-3σ controls mitotic translation to facilitate cytokinesis
EW Wilker, MATM van Vugt, SC Artim, PH Huang, CP Petersen, ...
Nature 446 (7133), 329-332, 2007
Receptor tyrosine kinase coactivation networks in cancer
AM Xu, PH Huang
Cancer research 70 (10), 3857-3860, 2010
Discoidin domain receptors: unique receptor tyrosine kinases in collagen-mediated signaling
HL Fu, RR Valiathan, R Arkwright, A Sohail, C Mihai, M Kumarasiri, ...
Journal of Biological Chemistry 288 (11), 7430-7437, 2013
Discoidin Domain Receptors Promote α1β1-and α2β1-Integrin Mediated Cell Adhesion to Collagen by Enhancing Integrin Activation
H Xu, D Bihan, F Chang, PH Huang, RW Farndale, B Leitinger
PLOS ONE 7 (12), e52209, 2012
The Pathobiology of Collagens in Glioma
LS Payne, PH Huang
Molecular Cancer Research 11 (10), 1129-1140, 2013
Uncovering therapeutic targets for glioblastoma: a systems biology approach
PH Huang, WK Cavenee, FB Furnari, FM White
Cell Cycle 6 (22), 2750-2754, 2007
Phosphoproteomics of collagen receptor networks reveals SHP-2 phosphorylation downstream of wild-type DDR2 and its lung cancer mutants
LK Iwai, LS Payne, MT Luczynski, F Chang, H Xu, RW Clinton, A Paul, ...
Biochemical Journal 454 (3), 501-513, 2013
EGFRvIV: a previously uncharacterized oncogenic mutant reveals a kinase autoinhibitory mechanism
G Pines, PH Huang, Y Zwang, FM White, Y Yarden
Oncogene 29 (43), 5850-5860, 2010
Targeting EGFR exon 20 insertion mutations in non-small cell lung cancer
S Vyse, PH Huang
Signal Transduction and Targeted Therapy 4 (1), 5, 2019
Phosphoproteomics: unraveling the signaling web
PH Huang, FM White
Molecular cell 31 (6), 777-781, 2008
Novel therapeutic approaches in chondrosarcoma
G Polychronidou, V Karavasilis, SM Pollack, PH Huang, A Lee, RL Jones
Future Oncology 13 (7), 637-648, 2017
A HIF-regulated VHL-PTP1B-src signaling axis identifies a therapeutic target in renal cell carcinoma
N Suwaki, E Vanhecke, KM Atkins, M Graf, K Swabey, P Huang, ...
Science Translational Medicine 3 (85), 85ra47-85ra47, 2011
Clinical and molecular spectrum of liposarcoma
ATJ Lee, K Thway, PH Huang, RL Jones
Journal of Clinical Oncology 36 (2), 151-159, 2017
Phosphotyrosine signaling analysis of site-specific mutations on EGFRvIII identifies determinants governing glioblastoma cell growth
PH Huang, ER Miraldi, AM Xu, VA Kundukulam, AM Del Rosario, ...
Molecular BioSystems 6 (7), 1227-1237, 2010
Direct Involvement of Retinoblastoma Family Proteins in DNA Repair by Non-homologous End-Joining
R Cook, G Zoumpoulidou, MT Luczynski, S Rieger, J Moquet, ...
Cell Reports 10 (12), 2006-2018, 2015
Dual Targeting of PDGFRα and FGFR1 Displays Synergistic Efficacy in Malignant Rhabdoid Tumors
JP Wong, JR Todd, MA Finetti, F McCarthy, M Broncel, S Vyse, ...
Cell Reports 17 (5), 1265-1275, 2016
Primary cilia mediate diverse kinase inhibitor resistance mechanisms in cancer
AD Jenks, S Vyse, JP Wong, E Kostaras, D Keller, T Burgoyne, ...
Cell reports 23 (10), 3042-3055, 2018
SWATH mass spectrometry as a tool for quantitative profiling of the matrisome
L Krasny, P Bland, N Kogata, P Wai, BA Howard, RC Natrajan, PH Huang
Journal of Proteomics, 2018
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