C A Seguin
C A Seguin
Verified email at schulich.uwo.ca
Cited by
Cited by
Isolation of human iPS cells using EOS lentiviral vectors to select for pluripotency
A Hotta, AYL Cheung, N Farra, K Vijayaragavan, CA Séguin, JS Draper, ...
Nature methods 6 (5), 370-376, 2009
Tumor necrosis factorα modulates matrix production and catabolism in nucleus pulposus tissue
CA Séguin, RM Pilliar, PJ Roughley, RA Kandel
Spine 30 (17), 1940-1948, 2005
Establishment of endoderm progenitors by SOX transcription factor expression in human embryonic stem cells
CA Séguin, JS Draper, A Nagy, J Rossant
Cell stem cell 3 (2), 182-195, 2008
Tissue engineered nucleus pulposus tissue formed on a porous calcium polyphosphate substrate
CA Séguin, MD Grynpas, RM Pilliar, SD Waldman, RA Kandel
Spine 29 (12), 1299-1306, 2004
TNFα suppresses link protein and type II collagen expression in chondrocytes: Role of MEK1/2 and NF‐κB signaling pathways
CA Séguin, SM Bernier
Journal of cellular physiology 197 (3), 356-369, 2003
Tracing notochord-derived cells using a Noto-cre mouse: implications for intervertebral disc development
MR McCann, OJ Tamplin, J Rossant, CA Séguin
Disease models & mechanisms 5 (1), 73-82, 2012
Differential regulation of matrix degrading enzymes in a TNFα-induced model of nucleus pulposus tissue degeneration
CA Séguin, M Bojarski, RM Pilliar, PJ Roughley, RA Kandel
Matrix biology 25 (7), 409-418, 2006
Geometric control of cardiomyogenic induction in human pluripotent stem cells
CL Bauwens, H Song, N Thavandiran, M Ungrin, S Massé, ...
Tissue Engineering Part A 17 (15-16), 1901-1909, 2011
TNF-α induces MMP2 gelatinase activity and MT1-MMP expression in an in vitro model of nucleus pulposus tissue degeneration
CA Séguin, RM Pilliar, JA Madri, RA Kandel
Spine 33 (4), 356-365, 2008
Formation of a nucleus pulposus-cartilage endplate construct in vitro
DJ Hamilton, CA Séguin, J Wang, RM Pilliar, RA Kandel
Biomaterials 27 (3), 397-405, 2006
Loss of equilibrative nucleoside transporter 1 in mice leads to progressive ectopic mineralization of spinal tissues resembling diffuse idiopathic skeletal hyperostosis in humans
S Warraich, DBJ Bone, D Quinonez, H Ii, DS Choi, DW Holdsworth, ...
Journal of Bone and Mineral Research 28 (5), 1135-1149, 2013
BMP signaling induces visceral endoderm differentiation of XEN cells and parietal endoderm
A Paca, CA Séguin, M Clements, M Ryczko, J Rossant, TA Rodriguez, ...
Developmental biology 361 (1), 90-102, 2012
Impaired intervertebral disc development and premature disc degeneration in mice with notochord‐specific deletion of CCN2
J Bedore, W Sha, MR McCann, S Liu, A Leask, CA Séguin
Arthritis & Rheumatism 65 (10), 2634-2644, 2013
Repeated exposure to high‐frequency low‐amplitude vibration induces degeneration of murine intervertebral discs and knee joints
MR McCann, P Patel, MA Pest, A Ratneswaran, G Lalli, KL Beaucage, ...
Arthritis & Rheumatology 67 (8), 2164-2175, 2015
Notochord cells in intervertebral disc development and degeneration
MR McCann, CA Séguin
Journal of developmental biology 4 (1), 3, 2016
Mechanosignaling activation of TGFβ maintains intervertebral disc homeostasis
Q Bian, L Ma, A Jain, JL Crane, K Kebaish, M Wan, Z Zhang, XE Guo, ...
Bone research 5 (1), 1-14, 2017
Targeting the extracellular matrix: Matricellular proteins regulate cell–extracellular matrix communication within distinct niches of the intervertebral disc
J Bedore, A Leask, CA Séguin
Matrix Biology 37, 124-130, 2014
Histological and reference system for the analysis of mouse intervertebral disc
V Tam, WCW Chan, VYL Leung, KSE Cheah, KMC Cheung, D Sakai, ...
Journal of Orthopaedic Research® 36 (1), 233-243, 2018
Exploiting notochord cells for stem cell-based regeneration of the intervertebral disc
MR McCann, CA Bacher, CA Séguin
Journal of cell communication and signaling 5 (1), 39-43, 2011
Ciliary parathyroid hormone signaling activates transforming growth factor-β to maintain intervertebral disc homeostasis during aging
L Zheng, Y Cao, S Ni, H Qi, Z Ling, X Xu, X Zou, T Wu, R Deng, B Hu, ...
Bone research 6 (1), 1-14, 2018
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