| Molecular mechanisms underlying nucleotide repeat expansion disorders I Malik, CP Kelley, ET Wang, PK Todd Nature reviews Molecular cell biology 22 (9), 589-607, 2021 | 176 | 2021 |
| Multicomponent synthesis of 2, 3-dihydrochromeno [4, 3-d] pyrazolo [3, 4-b] pyridine-1, 6-diones: a novel heterocyclic scaffold with antibacterial activity LV Frolova, I Malik, PY Uglinskii, S Rogelj, A Kornienko, IV Magedov Tetrahedron letters 52 (49), 6643-6645, 2011 | 121 | 2011 |
| Crystal structure of a transcribing RNA polymerase II complex reveals a complete transcription bubble CO Barnes, M Calero, I Malik, BW Graham, H Spahr, G Lin, AE Cohen, ... Molecular cell 59 (2), 258-269, 2015 | 107 | 2015 |
| One-pot multicomponent synthesis of diversely substituted 2-aminopyrroles. A short general synthesis of rigidins A, B, C, and D LV Frolova, NM Evdokimov, K Hayden, I Malik, S Rogelj, A Kornienko, ... Organic letters 13 (5), 1118-1121, 2011 | 91 | 2011 |
| Unprecedented C-2 arylation of indole with diazonium salts: Syntheses of 2, 3-disubstituted indoles and their antimicrobial activity S Daly, K Hayden, I Malik, N Porch, H Tang, S Rogelj, LV Frolova, ... Bioorganic & medicinal chemistry letters 21 (16), 4720-4723, 2011 | 46 | 2011 |
| Universal promoter scanning by Pol II during transcription initiation in Saccharomyces cerevisiae C Qiu, H Jin, I Vvedenskaya, JA Llenas, T Zhao, I Malik, AM Visbisky, ... Genome biology 21, 1-31, 2020 | 38 | 2020 |
| Wide-ranging and unexpected consequences of altered Pol II catalytic activity in vivo I Malik, C Qiu, T Snavely, CD Kaplan Nucleic Acids Research 45 (8), 4431-4451, 2017 | 36 | 2017 |
| Organismal benefits of transcription speed control at gene boundaries X Leng, M Ivanov, P Kindgren, I Malik, A Thieffry, P Brodersen, A Sandelin, ... EMBO reports 21 (4), e49315, 2020 | 31 | 2020 |
| Systematic analysis of cell cycle effects of common drugs leads to the discovery of a suppressive interaction between gemfibrozil and fluoxetine SA Hoose, C Duran, I Malik, S Eslamfam, SC Shasserre, SS Downing, ... PLoS One 7 (5), e36503, 2012 | 21 | 2012 |
| Non-canonical initiation factors modulate repeat-associated non-AUG translation KM Green, SL Miller, I Malik, PK Todd Human molecular genetics 31 (15), 2521-2534, 2022 | 20 | 2022 |
| SRSF protein kinase 1 modulates RAN translation and suppresses CGG repeat toxicity I Malik, YJ Tseng, SE Wright, K Zheng, P Ramaiyer, KM Green, PK Todd EMBO molecular medicine 13 (11), e14163, 2021 | 19 | 2021 |
| Green Chemistry. Reaction of Elemental Phosphorus (P4) and Elemental Sulfur with Protonodonor Reagents: New Methods for the Synthesis of Ammonium Salts of S, S … ES Batyeva, EK Badeeva, EV Platova, AT Gubaidullin, N Porch, ... Heteroatom Chemistry 24 (3), 163-167, 2013 | 9 | 2013 |
| Identification of PSMB5 as a genetic modifier of fragile X–associated tremor/ataxia syndrome HE Kong, J Lim, A Linsalata, Y Kang, I Malik, EG Allen, Y Cao, L Shubeck, ... Proceedings of the National Academy of Sciences 119 (22), e2118124119, 2022 | 8 | 2022 |
| Ribosomal quality control factors inhibit repeat-associated non-AUG translation from GC-rich repeats YJ Tseng, A Krans, I Malik, X Deng, E Yildirim, S Ovunc, EMH Tank, ... Nucleic Acids Research, gkae137, 2024 | 2 | 2024 |
| Thiolutin is a direct inhibitor of RNA Polymerase II C Qiu, I Malik, P Arora, AJ Laperuta, EM Pavlovic, S Ugochuckwu, M Naik, ... bioRxiv, 2021.05. 05.442806, 2021 | 2 | 2021 |
| Molecular mechanisms underlying nucleotide repeat expansion disorders (June, 10.1038/s41580-021-00382-6, 2021) I Malik, CP Kelley, ET Wang, PK Todd Nature Reviews Molecular Cell Biology 22 (9), 644-644, 2021 | 1 | 2021 |
| Thiolutin has complex effects in vivo but is a direct inhibitor of RNA polymerase II in vitro C Qiu, P Arora, I Malik, AJ Laperuta, EM Pavlovic, S Ugochukwu, M Naik, ... Nucleic Acids Research, gkad1258, 2024 | | 2024 |
| Dissecting the role of GGGGCC repeat RNA secondary structure in cellular toxicity associated with C9 FTD/ALS I Malik Alzheimer's & Dementia 19, e076175, 2023 | | 2023 |
| Dissecting the roles of EIF4G homologs reveals DAP5 as a modifier of CGG repeat-associated toxicity in a Drosophila model of FXTAS I Malik, YJ Tseng, CM Wieland, KM Green, K Zheng, K Calleja, PK Todd Neurobiology of Disease 184, 106212, 2023 | | 2023 |
| Repeat RNA structure and protein interactions influence RAN translation and neurodegenerative phenotypes in models of FTD and ALS I Malik, H Swaminathan, S Rouskin, PK Todd Alzheimer's & Dementia 19, e063489, 2023 | | 2023 |
Craig D. KaplanAssociate Professor, Department of Biological Sciences, University of PittsburghVerified email at pitt.edu
