The fate of medications evaluated for ischemic stroke pharmacotherapy over the period 1995–2015 X Chen, K Wang Acta Pharmaceutica Sinica B 6 (6), 522-530, 2016 | 91 | 2016 |
Inhibition of ANO1/TMEM16A induces apoptosis in human prostate carcinoma cells by activating TNF-α signaling Y Song, J Gao, L Guan, X Chen, J Gao, KW Wang Cell Death & Disease 9 (6), 703, 2018 | 61 | 2018 |
Severe deficiency of the voltage-gated sodium channel NaV1. 2 elevates neuronal excitability in adult mice J Zhang, X Chen, M Eaton, J Wu, Z Ma, S Lai, A Park, TS Ahmad, Z Que, ... Cell reports 36 (5), 2021 | 45 | 2021 |
Effect of magnolol on cerebral injury and blood brain barrier dysfunction induced by ischemia-reperfusion in vivo and in vitro X Liu, X Chen, Y Zhu, K Wang, Y Wang Metabolic Brain Disease 32, 1109-1118, 2017 | 43 | 2017 |
Deficiency of anti-inflammatory cytokine IL-4 leads to neural hyperexcitability and aggravates cerebral ischemia–reperfusion injury X Chen, J Zhang, Y Song, P Yang, Y Yang, Z Huang, K Wang Acta Pharmaceutica Sinica B 10 (9), 1634-1645, 2020 | 40 | 2020 |
Hyperexcitability and pharmacological responsiveness of cortical neurons derived from human iPSCs carrying epilepsy-associated sodium channel Nav1. 2-L1342P genetic variant Z Que, MI Olivero-Acosta, J Zhang, M Eaton, AM Tukker, X Chen, J Wu, ... Journal of Neuroscience 41 (49), 10194-10208, 2021 | 30 | 2021 |
Generation and basic characterization of a gene‐trap knockout mouse model of Scn2a with a substantial reduction of voltage‐gated sodium channel Nav1.2 … M Eaton, J Zhang, Z Ma, AC Park, E Lietzke, CM Romero, Y Liu, ... Genes, Brain and Behavior 20 (4), e12725, 2021 | 18 | 2021 |
Deficiency of autism-related Scn2a gene in mice disrupts sleep patterns and circadian rhythms Z Ma, M Eaton, Y Liu, J Zhang, X Chen, X Tu, Y Shi, Z Que, ... Neurobiology of disease 168, 105690, 2022 | 16 | 2022 |
Anticonvulsant effect of dipropofol by enhancing native GABA currents in cortical neurons in mice J Zhang, X Chen, M Kårbø, Y Zhao, L An, R Wang, KW Wang, Z Huang Journal of neurophysiology 120 (3), 1404-1414, 2018 | 11 | 2018 |
Inhibition of intracellular proton-sensitive Ca2+-permeable TRPV3 channels protects against ischemic brain injury X Chen, J Zhang, KW Wang Acta Pharmaceutica Sinica B 12 (5), 2330-2347, 2022 | 10 | 2022 |
PKA-RIIβ autophosphorylation modulates PKA activity and seizure phenotypes in mice J Zhang, C Zhang, X Chen, B Wang, W Ma, Y Yang, R Zheng, Z Huang Communications Biology 4 (1), 263, 2021 | 5 | 2021 |
Microglial over-pruning of synapses during development in autism-associated SCN2A-deficient mice and human cerebral organoids Y Yang, J Wu, J Zhang, X Chen, Z Que, K Wettschurack, B Deming, N Cui, ... Research Square, 2023 | 3 | 2023 |
002C-3 protects the brain against ischemia-reperfusion injury by inhibiting autophagy and stimulating CaMKK/CaMKIV/HDAC4 pathways in mice J liang Zhang, T Hu, X Liu, Y Zhu, X Chen, Y Liu, Y Wang Journal of Chinese Pharmaceutical Sciences 25 (8), 598-604, 2016 | | 2016 |