Jacob T Polaski
Jacob T Polaski
Postdoctoral Research Associate, Huntsman Cancer Institute
Verified email at
Cited by
Cited by
B12 cofactors directly stabilize an mRNA regulatory switch
JE Johnson Jr, FE Reyes, JT Polaski, RT Batey
Nature 492 (7427), 133-137, 2012
Recurrent RNA motifs as scaffolds for genetically encodable small-molecule biosensors
EB Porter, JT Polaski, MM Morck, RT Batey
Nature chemical biology 13 (3), 295-301, 2017
A multicolor riboswitch-based platform for imaging of RNA in live mammalian cells
E Braselmann, AJ Wierzba, JT Polaski, M Chromiński, ZE Holmes, ...
Nature chemical biology 14 (10), 964-971, 2018
RNA isoform screens uncover the essentiality and tumor-suppressor activity of ultraconserved poison exons
JD Thomas, JT Polaski, Q Feng, EJ De Neef, ER Hoppe, MV McSharry, ...
Nature Genetics 52 (1), 84-94, 2020
Minor intron retention drives clonal hematopoietic disorders and diverse cancer predisposition
D Inoue, JT Polaski, J Taylor, P Castel, S Chen, S Kobayashi, SJ Hogg, ...
Nature Genetics 53 (5), 707-718, 2021
Cobalamin riboswitches exhibit a broad range of ability to discriminate between methylcobalamin and adenosylcobalamin
JT Polaski, SM Webster, JE Johnson, RT Batey
Journal of Biological Chemistry 292 (28), 11650-11658, 2017
Mechanistic insights into cofactor-dependent coupling of RNA folding and mRNA transcription/translation by a cobalamin riboswitch
JT Polaski, ED Holmstrom, DJ Nesbitt, RT Batey
Cell reports 15 (5), 1100-1110, 2016
Single-molecule conformational dynamics of a biologically functional hydroxocobalamin riboswitch
ED Holmstrom, JT Polaski, RT Batey, DJ Nesbitt
Journal of the American Chemical Society 136 (48), 16832-16843, 2014
Synthetic introns enable splicing factor mutation-dependent targeting of cancer cells
K North, S Benbarche, B Liu, J Pangallo, S Chen, M Stahl, JP Bewersdorf, ...
Nature biotechnology 40 (7), 1103-1113, 2022
Rare and private spliceosomal gene mutations drive partial, complete, and dual phenocopies of hotspot alterations
J Pangallo, JJ Kiladjian, B Cassinat, A Renneville, J Taylor, JT Polaski, ...
Blood, The Journal of the American Society of Hematology 135 (13), 1032-1043, 2020
A highly coupled network of tertiary interactions in the SAM-I riboswitch and their role in regulatory tuning
C Wostenberg, P Ceres, JT Polaski, RT Batey
Journal of molecular biology 427 (22), 3473-3490, 2015
A functional genetic screen reveals sequence preferences within a key tertiary interaction in cobalamin riboswitches required for ligand selectivity
JT Polaski, OA Kletzien, LK Drogalis, RT Batey
Nucleic acids research 46 (17), 9094-9105, 2018
The origins and consequences of UPF1 variants in pancreatic adenosquamous carcinoma
JT Polaski, DB Udy, LF Escobar-Hoyos, G Askan, SD Leach, A Ventura, ...
Elife 10, e62209, 2021
Estrogen receptor alpha mutations regulate gene expression and cell growth in breast cancer through microRNAs
S Arnesen, JT Polaski, Z Blanchard, KS Osborne, AL Welm, ...
NAR cancer 5 (2), zcad027, 2023
Characterization of HCI-EC-23 a novel estrogen-and progesterone-responsive endometrial cancer cell line
CM Rush, Z Blanchard, JT Polaski, KS Osborne, K Osby, JM Vahrenkamp, ...
Scientific reports 12 (1), 19731, 2022
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