Mathias Heikenwälder
Mathias Heikenwälder
Univ. Prof. at Department Chronic Inflammation and Cancer, German Cancer Research Center (DKFZ))
Verified email at - Homepage
Cited by
Cited by
Senescence surveillance of pre-malignant hepatocytes limits liver cancer development
TW Kang, T Yevsa, N Woller, L Hoenicke, T Wuestefeld, D Dauch, ...
Nature 479 (7374), 547-551, 2011
Microglia emerge from erythromyeloid precursors via Pu. 1-and Irf8-dependent pathways
K Kierdorf, D Erny, T Goldmann, V Sander, C Schulz, EG Perdiguero, ...
Nature neuroscience 16 (3), 273-280, 2013
Microglia in the adult brain arise from Ly-6ChiCCR2+ monocytes only under defined host conditions
A Mildner, H Schmidt, M Nitsche, D Merkler, UK Hanisch, M Mack, ...
Nature neuroscience 10 (12), 1544-1553, 2007
From NASH to HCC: current concepts and future challenges
QM Anstee, HL Reeves, E Kotsiliti, O Govaere, M Heikenwalder
Nature reviews Gastroenterology & hepatology 16 (7), 411-428, 2019
The maternal microbiota drives early postnatal innate immune development
M Gomez de Agüero, SC Ganal-Vonarburg, T Fuhrer, S Rupp, ...
Science 351 (6279), 1296-1302, 2016
Specific and nonhepatotoxic degradation of nuclear hepatitis B virus cccDNA
J Lucifora, Y Xia, F Reisinger, K Zhang, D Stadler, X Cheng, MF Sprinzl, ...
Science 343 (6176), 1221-1228, 2014
Reversible microbial colonization of germ-free mice reveals the dynamics of IgA immune responses
S Hapfelmeier, MAE Lawson, E Slack, JK Kirundi, M Stoel, ...
Science 328 (5986), 1705-1709, 2010
The immunology of hepatocellular carcinoma
M Ringelhan, D Pfister, T O’Connor, E Pikarsky, M Heikenwalder
Nature immunology 19 (3), 222-232, 2018
Immunotherapies for hepatocellular carcinoma
JM Llovet, F Castet, M Heikenwalder, MK Maini, V Mazzaferro, DJ Pinato, ...
Nature reviews Clinical oncology 19 (3), 151-172, 2022
NASH limits anti-tumour surveillance in immunotherapy-treated HCC
D Pfister, NG Núñez, R Pinyol, O Govaere, M Pinter, M Szydlowska, ...
Nature 592 (7854), 450-456, 2021
mTOR regulates MAPKAPK2 translation to control the senescence-associated secretory phenotype
N Herranz, S Gallage, M Mellone, T Wuestefeld, S Klotz, CJ Hanley, ...
Nature cell biology 17 (9), 1205-1217, 2015
Metabolic activation of intrahepatic CD8+ T cells and NKT cells causes nonalcoholic steatohepatitis and liver cancer via cross-talk with hepatocytes
MJ Wolf, A Adili, K Piotrowitz, Z Abdullah, Y Boege, K Stemmer, ...
Cancer cell 26 (4), 549-564, 2014
A new type of microglia gene targeting shows TAK1 to be pivotal in CNS autoimmune inflammation
T Goldmann, P Wieghofer, PF Müller, Y Wolf, D Varol, S Yona, ...
Nature neuroscience 16 (11), 1618-1626, 2013
Peripherally applied Aβ-containing inoculates induce cerebral β-amyloidosis
YS Eisele, U Obermüller, G Heilbronner, F Baumann, SA Kaeser, ...
Science 330 (6006), 980-982, 2010
NAFLD causes selective CD4+ T lymphocyte loss and promotes hepatocarcinogenesis
C Ma, AH Kesarwala, T Eggert, J Medina-Echeverz, DE Kleiner, P Jin, ...
Nature 531 (7593), 253-257, 2016
Lymphoid follicle destruction and immunosuppression after repeated CpG oligodeoxynucleotide administration
M Heikenwalder, M Polymenidou, T Junt, C Sigurdson, H Wagner, S Akira, ...
Nature medicine 10 (2), 187-192, 2004
Distinct functions of senescence-associated immune responses in liver tumor surveillance and tumor progression
T Eggert, K Wolter, J Ji, C Ma, T Yevsa, S Klotz, J Medina-Echeverz, ...
Cancer cell 30 (4), 533-547, 2016
Molecular mechanisms of prion pathogenesis
A Aguzzi, C Sigurdson, M Heikenwaelder
Annu. Rev. Pathol. Mech. Dis. 3, 11-40, 2008
A lymphotoxin-driven pathway to hepatocellular carcinoma
J Haybaeck, N Zeller, MJ Wolf, A Weber, U Wagner, MO Kurrer, J Bremer, ...
Cancer cell 16 (4), 295-308, 2009
The Salmonella pathogenicity island (SPI)-2 and SPI-1 type III secretion systems allow Salmonella serovar typhimurium to trigger colitis via MyD88-dependent and MyD88 …
S Hapfelmeier, B Stecher, M Barthel, M Kremer, AJ Muller, ...
The Journal of Immunology 174 (3), 1675-1685, 2005
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