| Blocking an N-terminal acetylation–dependent protein interaction inhibits an E3 ligase DC Scott, JT Hammill, J Min, DY Rhee, M Connelly, VO Sviderskiy, ... Nature chemical biology 13 (8), 850-857, 2017 | 92 | 2017 |
| Discovery of an orally bioavailable inhibitor of defective in cullin neddylation 1 (DCN1)-mediated cullin neddylation JT Hammill, D Bhasin, DC Scott, J Min, Y Chen, Y Lu, L Yang, HS Kim, ... Journal of medicinal chemistry 61 (7), 2694-2706, 2018 | 52 | 2018 |
| Synthesis and evaluation of a novel deguelin derivative, L80, which disrupts ATP binding to the C-terminal domain of heat shock protein 90 SC Lee, HY Min, H Choi, HS Kim, KC Kim, SJ Park, MA Seong, JH Seo, ... Molecular Pharmacology 88 (2), 245-255, 2015 | 49 | 2015 |
| 2-(3-Fluoro-4-methylsulfonylaminophenyl) propanamides as potent transient receptor potential vanilloid 1 (TRPV1) antagonists: structure–activity relationships of 2-amino … MS Kim, HC Ryu, DW Kang, SH Cho, S Seo, YS Park, MY Kim, EJ Kwak, ... American Chemical Society, 2012 | 48 | 2012 |
| Discovery of novel pyrazolo-pyridone DCN1 inhibitors controlling cullin neddylation HS Kim, JT Hammill, DC Scott, Y Chen, J Min, J Rector, B Singh, ... Journal of medicinal chemistry 62 (18), 8429-8442, 2019 | 32 | 2019 |
| Discovery of nonpungent transient receptor potential vanilloid 1 (TRPV1) agonist as strong topical analgesic J Ann, HS Kim, SA Thorat, H Kim, HJ Ha, K Choi, YH Kim, M Kim, ... Journal of medicinal chemistry 63 (1), 418-424, 2019 | 31 | 2019 |
| Ring-truncated deguelin derivatives as potent Hypoxia Inducible Factor-1α (HIF-1α) inhibitors HS Kim, M Hong, SC Lee, HY Lee, YG Suh, DC Oh, JH Seo, H Choi, ... European journal of medicinal chemistry 104, 157-164, 2015 | 31 | 2015 |
| TRPV1 antagonist with high analgesic efficacy: 2-Thio pyridine C-region analogues of 2-(3-fluoro-4-methylsulfonylaminophenyl) propanamides TH Ha, HC Ryu, SE Kim, HS Kim, J Ann, PT Tran, VH Hoang, K Son, ... Bioorganic & medicinal chemistry 21 (21), 6657-6664, 2013 | 28 | 2013 |
| Synthesis and biological evaluation of C-ring truncated deguelin derivatives as heat shock protein 90 (HSP90) inhibitors HS Kim, M Hong, J Ann, S Yoon, CT Nguyen, SC Lee, HY Lee, YG Suh, ... Bioorganic & Medicinal Chemistry 24 (22), 6082-6093, 2016 | 27 | 2016 |
| 2-(3-Fluoro-4-methylsulfonylaminophenyl) propanamides as potent TRPV1 antagonists: Structure activity relationships of the 2-oxy pyridine C-region SA Thorat, DW Kang, HC Ryu, MS Kim, HS Kim, J Ann, T Ha, SE Kim, ... European journal of medicinal chemistry 64, 589-602, 2013 | 25 | 2013 |
| Investigation of B, C-ring truncated deguelin derivatives as heat shock protein 90 (HSP90) inhibitors for use as anti-breast cancer agents HS Kim, VH Hoang, M Hong, KC Kim, J Ann, CT Nguyen, JH Seo, H Choi, ... Bioorganic & Medicinal Chemistry 27 (7), 1370-1381, 2019 | 19 | 2019 |
| Seeking the elusive long-acting ozonide: discovery of Artefenomel (OZ439) HS Kim, JT Hammill, RK Guy Journal of Medicinal Chemistry 60 (7), 2651-2653, 2017 | 19 | 2017 |
| 2-Aryl substituted pyridine C-region analogues of 2-(3-fluoro-4-methylsulfonylaminophenyl) propanamides as highly potent TRPV1 antagonists HC Ryu, S Seo, MS Kim, MY Kim, HS Kim, J Ann, PT Tran, VH Hoang, ... Bioorganic & medicinal chemistry letters 24 (16), 4044-4047, 2014 | 19 | 2014 |
| 2-Alkyl/alkenyl substituted pyridine C-region analogues of 2-(3-fluoro-4-methylsulfonylaminophenyl) propanamides as highly potent TRPV1 antagonists HC Ryu, S Seo, SH Cho, HS Kim, A Jung, DW Kang, K Son, M Cui, ... Bioorganic & medicinal chemistry letters 24 (16), 4039-4043, 2014 | 17 | 2014 |
| α-Substituted 2-(3-fluoro-4-methylsulfonamidophenyl)acetamides as potent TRPV1 antagonists PT Tran, HS Kim, J Ann, SE Kim, C Kim, M Hong, VH Hoang, VTH Ngo, ... Bioorganic & medicinal chemistry letters 25 (11), 2326-2330, 2015 | 12 | 2015 |
| Improvement of oral bioavailability of pyrazolo-pyridone inhibitors of the interaction of DCN1/2 and UBE2M HS Kim, JT Hammill, DC Scott, Y Chen, AL Rice, W Pistel, B Singh, ... Journal of medicinal chemistry 64 (9), 5850-5862, 2021 | 10 | 2021 |
| α-Methylated simplified resiniferatoxin (sRTX) thiourea analogues as potent and stereospecific TRPV1 antagonists HS Kim, MK Jin, SU Kang, JO Lim, PT Tran, VH Hoang, J Ann, TH Ha, ... Bioorganic & medicinal chemistry letters 24 (12), 2685-2688, 2014 | 7 | 2014 |
| The SAR analysis of TRPV1 agonists with the α-methylated B-region Y Cho, MS Kim, HS Kim, J Ann, J Lee, LV Pearce, VA Pavlyukovets, ... Bioorganic & medicinal chemistry letters 22 (16), 5227-5231, 2012 | 7 | 2012 |
| 2-(4-Methylsulfonylaminophenyl) propanamide TRPV1 antagonists: Structure–activity relationships in the B and C-regions W Sun, K Liu, HC Ryu, DW Kang, YS Kim, MS Kim, Y Cho, RS Bhondwe, ... Bioorganic & medicinal chemistry 20 (3), 1310-1318, 2012 | 7 | 2012 |
| Amino-substituted 3-Aryl-and 3-heteroarylquinolines as potential antileishmanial agents JT Hammill, VM Sviripa, LM Kril, D Ortiz, CM Fargo, HS Kim, Y Chen, ... Journal of Medicinal Chemistry 64 (16), 12152-12162, 2021 | 6 | 2021 |
