The art and science of total synthesis at the dawn of the twenty‐first century KC Nicolaou, D Vourloumis, N Winssinger, PS Baran Angewandte Chemie International Edition 39 (1), 44-122, 2000 | 930 | 2000 |
Chemistry, biology, and medicine of the glycopeptide antibiotics KC Nicolaou, CNC Boddy, S Bräse, N Winssinger Angewandte Chemie International Edition 38 (15), 2096-2152, 1999 | 880 | 1999 |
Synthesis of epothilones A and B in solid and solution phase KC Nicolaou, N Winssinger, J Pastor, S Ninkovic, F Sarabia, Y He, ... Nature 387 (6630), 268-272, 1997 | 646 | 1997 |
Designed Epothilones: Combinatorial Synthesis, Tubulin Assembly Properties, abd Cytotoxic Action against Taxol‐Resistant Tumor Cells KC Nicolaou, D Vourloumis, T Li, J Pastor, N Winssinger, Y He, ... Angewandte Chemie International Edition in English 36 (19), 2097-2103, 1997 | 340 | 1997 |
A general and highly efficient solid phase synthesis of oligosaccharides. Total synthesis of a heptasaccharide phytoalexin elicitor (HPE) KC Nicolaou, N Winssinger, J Pastor, F DeRoose Journal of the American Chemical Society 119 (2), 449-450, 1997 | 301 | 1997 |
Profiling protein function with small molecule microarrays N Winssinger, S Ficarro, PG Schultz, JL Harris Proceedings of the National Academy of Sciences 99 (17), 11139-11144, 2002 | 225 | 2002 |
Cysteine mapping in conformationally distinct kinase nucleotide binding sites: application to the design of selective covalent inhibitors E Leproult, S Barluenga, D Moras, JM Wurtz, N Winssinger Journal of medicinal chemistry 54 (5), 1347-1355, 2011 | 223 | 2011 |
Der stand der totalsynthese zu beginn des 21. jahrhunderts KC Nicolaou, D Vourloumis, N Winssinger, PS Baran Angewandte Chemie 112 (1), 46-126, 2000 | 212 | 2000 |
Total synthesis of vancomycin KC Nicolaou, HJ Mitchell, NF Jain, N Winssinger, R Hughes, T Bando Angewandte Chemie International Edition 38 (1‐2), 240-244, 1999 | 210 | 1999 |
Solid and solution phase synthesis and biological evaluation of combinatorial sarcodictyin libraries KC Nicolaou, N Winssinger, D Vourloumis, T Ohshima, S Kim, ... Journal of the American Chemical Society 120 (42), 10814-10826, 1998 | 210 | 1998 |
Target‐accelerated combinatorial synthesis and discovery of highly potent antibiotics effective against vancomycin‐resistant bacteria KC Nicolaou, R Hughes, SY Cho, N Winssinger, C Smethurst, ... Angewandte Chemie International Edition 39 (21), 3823-3828, 2000 | 200 | 2000 |
Chemie, Biologie und medizinische Anwendungen der Glycopeptid‐Antibiotika KC Nicolaou, CNC Boddy, S Bräse, N Winssinger Angewandte Chemie 111 (15), 2230-2287, 1999 | 191 | 1999 |
Development of a functionalized xenon biosensor MM Spence, EJ Ruiz, SM Rubin, TJ Lowery, N Winssinger, PG Schultz, ... Journal of the American Chemical Society 126 (46), 15287-15294, 2004 | 189 | 2004 |
Chemistry and biology of resorcylic acid lactones N Winssinger, S Barluenga Chemical communications, 22-36, 2007 | 184 | 2007 |
Imaging of mRNA in live cells using nucleic acid-templated reduction of azidorhodamine probes Z Pianowski, K Gorska, L Oswald, CA Merten, N Winssinger Journal of the American Chemical Society 131 (18), 6492-6497, 2009 | 180 | 2009 |
The molecular chaperone Hsp90α is required for meiotic progression of spermatocytes beyond pachytene in the mouse I Grad, CR Cederroth, J Walicki, C Grey, S Barluenga, N Winssinger, ... PloS one 5 (12), e15770, 2010 | 177 | 2010 |
Synthesis and biological evaluation of vancomycin dimers with potent activity against vancomycin‐resistant bacteria: target‐accelerated combinatorial synthesis KC Nicolaou, R Hughes, SY Cho, N Winssinger, H Labischinski, ... Chemistry–A European Journal 7 (17), 3824-3843, 2001 | 175 | 2001 |
PNA-encoded protease substrate microarrays N Winssinger, R Damoiseaux, DC Tully, BH Geierstanger, K Burdick, ... Chemistry & biology 11 (10), 1351-1360, 2004 | 171 | 2004 |
Peptide nucleic acid (PNA) and its applications in chemical biology, diagnostics, and therapeutics J Saarbach, PM Sabale, N Winssinger Current opinion in chemical biology 52, 112-124, 2019 | 165 | 2019 |
Design, synthesis, and biological evaluation of HSP90 inhibitors based on conformational analysis of radicicol and its analogues E Moulin, V Zoete, S Barluenga, M Karplus, N Winssinger Journal of the American Chemical Society 127 (19), 6999-7004, 2005 | 165 | 2005 |