High-definition spatial transcriptomics for in situ tissue profiling S Vickovic, G Eraslan, F Salmén, J Klughammer, L Stenbeck, D Schapiro, ... Nature methods 16 (10), 987-990, 2019 | 1000 | 2019 |
Pooled CRISPR screening with single-cell transcriptome readout P Datlinger, AF Rendeiro, C Schmidl, T Krausgruber, P Traxler, ... Nature methods 14 (3), 297-301, 2017 | 999 | 2017 |
Specification of tissue-resident macrophages during organogenesis E Mass, I Ballesteros, M Farlik, F Halbritter, P Günther, L Crozet, ... Science 353 (6304), aaf4238, 2016 | 859 | 2016 |
A single-cell and single-nucleus RNA-Seq toolbox for fresh and frozen human tumors M Slyper, CBM Porter, O Ashenberg, J Waldman, E Drokhlyansky, ... Nature medicine 26 (5), 792-802, 2020 | 551 | 2020 |
Single-cell DNA methylome sequencing and bioinformatic inference of epigenomic cell-state dynamics M Farlik, NC Sheffield, A Nuzzo, P Datlinger, A Schönegger, ... Cell reports 10 (8), 1386-1397, 2015 | 480 | 2015 |
Artemisinins target GABAA receptor signaling and impair α cell identity J Li, T Casteels, T Frogne, C Ingvorsen, C Honore, M Courtney, ... Cell 168 (1), 86-100. e15, 2017 | 408 | 2017 |
Expansion sequencing: Spatially precise in situ transcriptomics in intact biological systems S Alon, DR Goodwin, A Sinha, AT Wassie, F Chen, ER Daugharthy, ... Science 371 (6528), eaax2656, 2021 | 356 | 2021 |
Genomic and phenotypic insights from an atlas of genetic effects on DNA methylation JL Min, G Hemani, E Hannon, KF Dekkers, J Castillo-Fernandez, R Luijk, ... Nature genetics 53 (9), 1311-1321, 2021 | 299 | 2021 |
The DNA methylation landscape of glioblastoma disease progression shows extensive heterogeneity in time and space J Klughammer, B Kiesel, T Roetzer, N Fortelny, A Nemc, KH Nenning, ... Nature medicine 24 (10), 1611-1624, 2018 | 287 | 2018 |
DNA methylation dynamics of human hematopoietic stem cell differentiation M Farlik, F Halbritter, F Müller, FA Choudry, P Ebert, J Klughammer, ... Cell stem cell 19 (6), 808-822, 2016 | 282 | 2016 |
Single‐cell transcriptomes reveal characteristic features of human pancreatic islet cell types J Li, J Klughammer, M Farlik, T Penz, A Spittler, C Barbieux, E Berishvili, ... EMBO reports 17 (2), 178-187, 2016 | 253 | 2016 |
DNA methylation heterogeneity defines a disease spectrum in Ewing sarcoma NC Sheffield, G Pierron, J Klughammer, P Datlinger, A Schönegger, ... Nature medicine 23 (3), 386-395, 2017 | 244 | 2017 |
Epigenetic encoding, heritability and plasticity of glioma transcriptional cell states R Chaligne, F Gaiti, D Silverbush, JS Schiffman, HR Weisman, L Kluegel, ... Nature genetics 53 (10), 1469-1479, 2021 | 171 | 2021 |
SM-Omics is an automated platform for high-throughput spatial multi-omics S Vickovic, B Lötstedt, J Klughammer, S Mages, Å Segerstolpe, ... Nature communications 13 (1), 795, 2022 | 117 | 2022 |
Divergent expression regulation of gonad development genes in medaka shows incomplete conservation of the downstream regulatory network of vertebrate sex determination A Herpin, MC Adolfi, B Nicol, M Hinzmann, C Schmidt, J Klughammer, ... Molecular biology and evolution 30 (10), 2328-2346, 2013 | 98 | 2013 |
Parental micronutrient deficiency distorts liver DNA methylation and expression of lipid genes associated with a fatty-liver-like phenotype in offspring KH Skjærven, LM Jakt, JMO Fernandes, JA Dahl, AC Adam, ... Scientific reports 8 (1), 3055, 2018 | 59 | 2018 |
The ERBB-STAT3 axis drives Tasmanian devil facial tumor disease L Kosack, B Wingelhofer, A Popa, A Orlova, B Agerer, B Vilagos, P Majek, ... Cancer Cell 35 (1), 125-139. e9, 2019 | 49 | 2019 |
Comparative analysis of genome-scale, base-resolution DNA methylation profiles across 580 animal species J Klughammer, D Romanovskaia, A Nemc, A Posautz, CA Seid, ... Nature Communications 14 (1), 232, 2023 | 48 | 2023 |
TACCO unifies annotation transfer and decomposition of cell identities for single-cell and spatial omics S Mages, N Moriel, I Avraham-Davidi, E Murray, J Watter, F Chen, ... Nature biotechnology 41 (10), 1465-1473, 2023 | 36 | 2023 |
Differential DNA methylation analysis without a reference genome J Klughammer, P Datlinger, D Printz, NC Sheffield, M Farlik, J Hadler, ... Cell Reports 13 (11), 2621-2633, 2015 | 34 | 2015 |