| Complex multi-enhancer contacts captured by genome architecture mapping RA Beagrie, A Scialdone, M Schueler, DCA Kraemer, M Chotalia, SQ Xie, ... Nature 543 (7646), 519-524, 2017 | 573 | 2017 |
| Polycomb associates genome-wide with a specific RNA polymerase II variant, and regulates metabolic genes in ESCs E Brookes, I de Santiago, D Hebenstreit, KJ Morris, T Carroll, SQ Xie, ... Cell stem cell 10 (2), 157-170, 2012 | 304 | 2012 |
| Impact of artifact removal on ChIP quality metrics in ChIP-seq and ChIP-exo data TS Carroll, Z Liang, R Salama, R Stark, I de Santiago Frontiers in genetics 5, 75, 2014 | 200 | 2014 |
| Master regulators of FGFR2 signalling and breast cancer risk MNC Fletcher, MAA Castro, X Wang, I De Santiago, M O’Reilly, SF Chin, ... Nature communications 4 (1), 2464, 2013 | 183 | 2013 |
| Regulators of genetic risk of breast cancer identified by integrative network analysis MAA Castro, I de Santiago, TM Campbell, C Vaughn, TE Hickey, E Ross, ... Nature genetics 48 (1), 12-21, 2016 | 148 | 2016 |
| Fine-scale mapping of the FGFR2 breast cancer risk locus: putative functional variants differentially bind FOXA1 and E2F1 KB Meyer, M O’Reilly, K Michailidou, S Carlebur, SL Edwards, JD French, ... The American Journal of Human Genetics 93 (6), 1046-1060, 2013 | 141 | 2013 |
| Evidence that breast cancer risk at the 2q35 locus is mediated through IGFBP5 regulation M Ghoussaini, SL Edwards, K Michailidou, S Nord, R Cowper-Sal· lari, ... Nature communications 5 (1), 4999, 2014 | 128 | 2014 |
| Combined image and genomic analysis of high-grade serous ovarian cancer reveals PTEN loss as a common driver event and prognostic classifier FC Martins, I Santiago, A Trinh, J Xian, A Guo, K Sayal, M Jimenez-Linan, ... Genome biology 15 (12), 1-15, 2014 | 99 | 2014 |
| Accumulated Metabolites of Hydroxybutyric Acid Serve as Diagnostic and Prognostic Biomarkers of Ovarian High-Grade Serous CarcinomasMetabolic Biomarkers for Ovarian High-Grade … M Hilvo, I De Santiago, P Gopalacharyulu, WD Schmitt, J Budczies, ... Cancer research 76 (4), 796-804, 2016 | 77 | 2016 |
| Active and poised promoter states drive folding of the extended HoxB locus in mouse embryonic stem cells M Barbieri, SQ Xie, E Torlai Triglia, AM Chiariello, S Bianco, I de Santiago, ... Nature structural & molecular biology 24 (6), 515-524, 2017 | 75 | 2017 |
| Eukaryotic gene regulation in three dimensions and its impact on genome evolution MM Babu, SC Janga, I de Santiago, A Pombo Current opinion in genetics & development 18 (6), 571-582, 2008 | 58 | 2008 |
| FGFR2 risk SNPs confer breast cancer risk by augmenting oestrogen responsiveness TM Campbell, MAA Castro, I de Santiago, MNC Fletcher, S Halim, ... Carcinogenesis 37 (8), 741-750, 2016 | 46 | 2016 |
| Master Regulators of Oncogenic KRAS Response in Pancreatic Cancer: An Integrative Network Biology Analysis S Sivakumar, I de Santiago, L Chlon, F Markowetz PLoS medicine 14 (1), e1002223, 2017 | 42 | 2017 |
| RNA polymerase II primes Polycomb‐repressed developmental genes throughout terminal neuronal differentiation C Ferrai, E Torlai Triglia, JR Risner‐Janiczek, T Rito, OJL Rackham, ... Molecular systems biology 13 (10), 946, 2017 | 35 | 2017 |
| Immunophenotypes of pancreatic ductal adenocarcinoma: Meta‐analysis of transcriptional subtypes I de Santiago, C Yau, L Heij, MR Middleton, F Markowetz, HI Grabsch, ... International journal of cancer 145 (4), 1125-1137, 2019 | 32 | 2019 |
| BaalChIP: Bayesian analysis of allele-specific transcription factor binding in cancer genomes I de Santiago, W Liu, K Yuan, M O’Reilly, CSR Chilamakuri, BAJ Ponder, ... Genome biology 18, 1-17, 2017 | 24 | 2017 |
| Analysis of ChIP-seq data in R/Bioconductor I de Santiago, T Carroll Chromatin Immunoprecipitation: Methods and Protocols, 195-226, 2018 | 12 | 2018 |
| Eukaryotic gene regulation in three dimensions and its impact on genome evolution M Madan Babu, SC Janga, I de Santiago, A Pombo CURRENT OPINION IN GENETICS AND DEVELOPMENT 18 (6), 571-582, 2008 | 7 | 2008 |
| Clonal somatic copy number altered driver events inform drug sensitivity in high-grade serous ovarian cancer FC Martins, DL Couturier, I De Santiago, CM Sauer, M Vias, M Angelova, ... Nature Communications 13 (1), 6360, 2022 | 3 | 2022 |
| Big data and artificial intelligence (AI) are poised to transform infertility healthcare I de Santiago, L Polanski Preprints, 2020 | 2 | 2020 |
Florian MarkowetzCancer Research UK Cambridge InstituteVerified email at cruk.cam.ac.uk
