| A test for Creutzfeldt–Jakob disease using nasal brushings CD Orrú, M Bongianni, G Tonoli, S Ferrari, AG Hughson, BR Groveman, ... New England Journal of Medicine 371 (6), 519-529, 2014 | 374 | 2014 |
| Rapid and ultra-sensitive quantitation of disease-associated α-synuclein seeds in brain and cerebrospinal fluid by αSyn RT-QuIC BR Groveman, CD Orrù, AG Hughson, LD Raymond, G Zanusso, B Ghetti, ... Acta neuropathologica communications 6, 1-10, 2018 | 294 | 2018 |
| Rapid and sensitive RT-QuIC detection of human Creutzfeldt-Jakob disease using cerebrospinal fluid CD Orrú, BR Groveman, AG Hughson, G Zanusso, MB Coulthart, ... MBio 6 (1), 10.1128/mbio. 02451-14, 2015 | 225 | 2015 |
| Diagnosis of human prion disease using real-time quaking-induced conversion testing of olfactory mucosa and cerebrospinal fluid samples M Bongianni, C Orrù, BR Groveman, L Sacchetto, M Fiorini, G Tonoli, ... JAMA neurology 74 (2), 155-162, 2017 | 203 | 2017 |
| Parallel in-register intermolecular β-sheet architectures for prion-seeded prion protein (PrP) amyloids BR Groveman, MA Dolan, LM Taubner, A Kraus, RB Wickner, B Caughey Journal of Biological Chemistry 289 (35), 24129-24142, 2014 | 193 | 2014 |
| Bank vole prion protein as an apparently universal substrate for RT-QuIC-based detection and discrimination of prion strains CD Orrú, BR Groveman, LD Raymond, AG Hughson, R Nonno, W Zou, ... PLoS pathogens 11 (6), e1004983, 2015 | 170 | 2015 |
| Prion seeding activity and infectivity in skin samples from patients with sporadic Creutzfeldt-Jakob disease CD Orrú, J Yuan, BS Appleby, B Li, Y Li, D Winner, Z Wang, YA Zhan, ... Science translational medicine 9 (417), eaam7785, 2017 | 126 | 2017 |
| The real-time quaking-induced conversion assay for detection of human prion disease and study of other protein misfolding diseases M Schmitz, M Cramm, F Llorens, D Müller-Cramm, S Collins, R Atarashi, ... Nature protocols 11 (11), 2233-2242, 2016 | 124 | 2016 |
| Prions and the potential transmissibility of protein misfolding diseases A Kraus, BR Groveman, B Caughey Annual review of microbiology 67, 543-564, 2013 | 110 | 2013 |
| High diagnostic performance of independent alpha-synuclein seed amplification assays for detection of early Parkinson’s disease MJ Russo, CD Orru, L Concha-Marambio, S Giaisi, BR Groveman, ... Acta neuropathologica communications 9, 1-13, 2021 | 99 | 2021 |
| Extended and direct evaluation of RT‐Qu IC assays for Creutzfeldt‐Jakob disease diagnosis BR Groveman, CD Orrú, AG Hughson, M Bongianni, M Fiorini, ... Annals of Clinical and Translational Neurology 4 (2), 139-144, 2017 | 93 | 2017 |
| Sporadic Creutzfeldt-Jakob disease prion infection of human cerebral organoids BR Groveman, ST Foliaki, CD Orru, G Zanusso, JA Carroll, B Race, ... Acta neuropathologica communications 7, 1-12, 2019 | 82 | 2019 |
| Inactivation of prions and amyloid seeds with hypochlorous acid AG Hughson, B Race, A Kraus, LR Sangaré, L Robins, BR Groveman, ... PLoS pathogens 12 (9), e1005914, 2016 | 77 | 2016 |
| Factors that improve RT-QuIC detection of prion seeding activity CD Orrú, AG Hughson, BR Groveman, KJ Campbell, KJ Anson, M Manca, ... Viruses 8 (5), 140, 2016 | 76 | 2016 |
| The regulation of N‐methyl‐d‐aspartate receptors by Src kinase BR Groveman, S Feng, XQ Fang, M Pflueger, SX Lin, EA Bienkiewicz, ... The FEBS journal 279 (1), 20-28, 2012 | 69 | 2012 |
| Ultrasensitive RT-QuIC seed amplification assays for disease-associated tau, α-synuclein, and prion aggregates E Saijo, BR Groveman, A Kraus, M Metrick, CD Orrù, AG Hughson, ... Protein Misfolding Diseases: Methods and Protocols, 19-37, 2019 | 63 | 2019 |
| RT-QuIC assays for prion disease detection and diagnostics CD Orrù, BR Groveman, AG Hughson, M Manca, LD Raymond, ... Prions: Methods and Protocols, 185-203, 2017 | 63 | 2017 |
| Detection and discrimination of classical and atypical L-type bovine spongiform encephalopathy by real-time quaking-induced conversion CD Orrú, A Favole, C Corona, M Mazza, M Manca, BR Groveman, ... Journal of clinical microbiology 53 (4), 1115-1120, 2015 | 60 | 2015 |
| Charge neutralization of the central lysine cluster in prion protein (PrP) promotes PrPSc-like folding of recombinant PrP amyloids BR Groveman, A Kraus, LD Raymond, MA Dolan, KJ Anson, DW Dorward, ... Journal of Biological Chemistry 290 (2), 1119-1128, 2015 | 51 | 2015 |
| Prion seeds distribute throughout the eyes of sporadic Creutzfeldt-Jakob disease patients CD Orrù, K Soldau, C Cordano, J Llibre-Guerra, AJ Green, H Sanchez, ... MBio 9 (6), 10.1128/mbio. 02095-18, 2018 | 49 | 2018 |
