| Mutant huntingtin causes metabolic imbalance by disruption of hypothalamic neurocircuits S Hult, R Soylu, T Björklund, BF Belgardt, J Mauer, JC Brüning, D Kirik, ... Cell metabolism 13 (4), 428-439, 2011 | 121 | 2011 |
| Hypothalamic expression of mutant huntingtin contributes to the development of depressive-like behavior in the BAC transgenic mouse model of Huntington's disease S Hult Lundh, N Nilsson, R Soylu, D Kirik, Å Petersén Human molecular genetics 22 (17), 3485-3497, 2013 | 81 | 2013 |
| Human α-synuclein overexpression in a mouse model of Parkinson’s disease leads to vascular pathology, blood brain barrier leakage and pericyte activation O Elabi, A Gaceb, R Carlsson, T Padel, R Soylu-Kucharz, I Cortijo, W Li, ... Scientific reports 11 (1), 1120, 2021 | 68 | 2021 |
| A point mutation in the dynein heavy chain gene leads to striatal atrophy and compromises neurite outgrowth of striatal neurons KE Braunstein, J Eschbach, K Ròna-Vörös, R Soylu, E Mikrouli, Y Larmet, ... Human molecular genetics 19 (22), 4385-4398, 2010 | 68 | 2010 |
| Increased intestinal permeability and gut dysbiosis in the R6/2 mouse model of Huntington’s disease TL Stan, R Soylu-Kucharz, S Burleigh, O Prykhodko, L Cao, N Franke, ... Scientific reports 10 (1), 18270, 2020 | 67 | 2020 |
| Increased numbers of orexin/hypocretin neurons in a genetic rat depression model E Mikrouli, G Wörtwein, R Soylu, AA Mathé, Å Petersén Neuropeptides 45 (6), 401-406, 2011 | 62 | 2011 |
| Apolipoprotein M-bound sphingosine-1-phosphate regulates blood–brain barrier paracellular permeability and transcytosis M Mathiesen Janiurek, R Soylu-Kucharz, C Christoffersen, K Kucharz, ... Elife 8, e49405, 2019 | 57 | 2019 |
| Neurofilament light protein in CSF and blood is associated with neurodegeneration and disease severity in Huntington’s disease R6/2 mice R Soylu-Kucharz, Å Sandelius, M Sjögren, K Blennow, EJ Wild, ... Scientific reports 7 (1), 14114, 2017 | 55 | 2017 |
| Hypothalamic and neuroendocrine changes in Huntington's disease S Hult, K Schultz, R Soylu, A Petersen Current drug targets 11 (10), 1237-1249, 2010 | 51 | 2010 |
| SIRT1 is increased in affected brain regions and hypothalamic metabolic pathways are altered in Huntington disease B Baldo, S Gabery, R Soylu‐Kucharz, RY Cheong, JB Henningsen, ... Neuropathology and applied neurobiology 45 (4), 361-379, 2019 | 32 | 2019 |
| Maintenance of basal levels of autophagy in Huntington’s disease mouse models displaying metabolic dysfunction B Baldo, R Soylu, Å Petersén PloS one 8 (12), e83050, 2013 | 29 | 2013 |
| Expression of mutant huntingtin in leptin receptor-expressing neurons does not control the metabolic and psychiatric phenotype of the BACHD mouse SH Lundh, R Soylu, Å Petersén PloS one 7 (12), e51168, 2012 | 26 | 2012 |
| Low dietary protein content alleviates motor symptoms in mice with mutant dynactin/dynein-mediated neurodegeneration D Wiesner, J Sinniger, A Henriques, S Dieterlé, HP Müller, V Rasche, ... Human molecular genetics 24 (8), 2228-2240, 2015 | 21 | 2015 |
| Metabolic and behavioral effects of mutant huntingtin deletion in Sim1 neurons in the BACHD mouse model of Huntington’s disease R Soylu-Kucharz, B Baldo, Å Petersén Scientific reports 6 (1), 28322, 2016 | 19 | 2016 |
| Leptin deficiency reverses high metabolic state and weight loss without affecting central pathology in the R6/2 mouse model of Huntington's disease M Sjögren, R Soylu-Kucharz, U Dandunna, TL Stan, M Cavalera, ... Neurobiology of disease 132, 104560, 2019 | 17 | 2019 |
| Hypothalamic overexpression of mutant huntingtin causes dysregulation of brown adipose tissue R Soylu-Kucharz, N Adlesic, B Baldo, D Kirik, Å Petersén Scientific reports 5 (1), 14598, 2015 | 16 | 2015 |
| Characterization of a rat model of Huntington’s disease based on targeted expression of mutant huntingtin in the forebrain using adeno‐associated viral vectors S Gabery, MU Sajjad, S Hult, R Soylu, D Kirik, Å Petersén European Journal of Neuroscience 36 (6), 2789-2800, 2012 | 16 | 2012 |
| Hypothalamic expression of huntingtin causes distinct metabolic changes in Huntington's disease mice E Dickson, R Soylu-Kucharz, Å Petersén, M Björkqvist Molecular Metabolism 57, 101439, 2022 | 12 | 2022 |
| Preserved blood-brain barrier and neurovascular coupling in female 5xFAD model of Alzheimer’s disease O Zhukov, C He, R Soylu-Kucharz, C Cai, AD Lauritzen, BI Aldana, ... Frontiers in Aging Neuroscience 15, 1089005, 2023 | 7 | 2023 |
| Microarray profiling of hypothalamic gene expression changes in Huntington’s disease mouse models E Dickson, AS Dwijesha, N Andersson, S Lundh, M Björkqvist, Å Petersén, ... Frontiers in Neuroscience 16, 1027269, 2022 | 4 | 2022 |
