M. Luisa Iruela-Arispe
M. Luisa Iruela-Arispe
Professor and Chair Dept. Cell & Dev. Biology
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Dll4 signalling through Notch1 regulates formation of tip cells during angiogenesis
M Hellström, LK Phng, JJ Hofmann, E Wallgard, L Coultas, P Lindblom, ...
Nature 445 (7129), 776-780, 2007
Autocrine VEGF signaling is required for vascular homeostasis
S Lee, TT Chen, CL Barber, MC Jordan, J Murdock, S Desai, N Ferrara, ...
Cell 130 (4), 691-703, 2007
Myc-driven murine prostate cancer shares molecular features with human prostate tumors
K Ellwood-Yen, TG Graeber, J Wongvipat, ML Iruela-Arispe, JF Zhang, ...
Cancer cell 4 (3), 223-238, 2003
Processing of VEGF-A by matrix metalloproteinases regulates bioavailability and vascular patterning in tumors
S Lee, SM Jilani, GV Nikolova, D Carpizo, ML Iruela-Arispe
The Journal of cell biology 169 (4), 681-691, 2005
Fate tracing reveals the endothelial origin of hematopoietic stem cells
AC Zovein, JJ Hofmann, M Lynch, WJ French, KA Turlo, Y Yang, ...
Cell stem cell 3 (6), 625-636, 2008
Dicer-dependent endothelial microRNAs are necessary for postnatal angiogenesis
Y Suárez, C Fernández-Hernando, J Yu, SA Gerber, KD Harrison, ...
Proceedings of the National Academy of Sciences 105 (37), 14082-14087, 2008
PDGF-BB modulates endothelial proliferation and angiogenesis in vitro via PDGF beta-receptors.
EJ Battegay, J Rupp, L Iruela-Arispe, EH Sage, M Pech
The Journal of cell biology 125 (4), 917-928, 1994
Thrombospondin-1 suppresses spontaneous tumor growth and inhibits activation of matrix metalloproteinase-9 and mobilization of vascular endothelial growth factor
JC Rodríguez-Manzaneque, TF Lane, MA Ortega, RO Hynes, J Lawler, ...
Proceedings of the National Academy of Sciences 98 (22), 12485-12490, 2001
METH-1, a human ortholog of ADAMTS-1, and METH-2 are members of a new family of proteins with angio-inhibitory activity
F Vázquez, G Hastings, MA Ortega, TF Lane, S Oikemus, M Lombardo, ...
Journal of Biological Chemistry 274 (33), 23349-23357, 1999
Vascular expression of Notch pathway receptors and ligands is restricted to arterial vessels
N Villa, L Walker, CE Lindsell, J Gasson, ML Iruela-Arispe, G Weinmaster
Mechanisms of development 108 (1-2), 161-164, 2001
Vascular Stroma Formation in Carcinoma in Situ, Invasive Carcinoma, and Metastatic Carcinoma of the Breast
LF Brown, AJ Guidi, SJ Schnitt, L Van De Water, ML Iruela-Arispe, TK Yeo, ...
Clinical Cancer Research 5 (5), 1041-1056, 1999
Versican V1 proteolysis in human aorta in vivo occurs at the Glu441-Ala442 bond, a site that is cleaved by recombinant ADAMTS-1 and ADAMTS-4
JD Sandy, J Westling, RD Kenagy, ML Iruela-Arispe, C Verscharen, ...
Journal of Biological Chemistry 276 (16), 13372-13378, 2001
Consensus guidelines for the use and interpretation of angiogenesis assays
P Nowak-Sliwinska, K Alitalo, E Allen, A Anisimov, AC Aplin, R Auerbach, ...
Angiogenesis 21, 425-532, 2018
VE‐Cadherin‐Cre‐recombinase transgenic mouse: a tool for lineage analysis and gene deletion in endothelial cells
JA Alva, AC Zovein, A Monvoisin, T Murphy, A Salazar, NL Harvey, ...
Developmental dynamics: an official publication of the American Association …, 2006
Inactivation of erythropoietin leads to defects in cardiac morphogenesis
H Wu, SH Lee, J Gao, X Liu, ML Iruela-Arispe
Development 126 (16), 3597-3605, 1999
Angiogenesis: a dynamic balance of stimulators and inhibitors
LM Iruela-Arispe, HF Dvorak
Thrombosis and haemostasis 78 (07), 672-677, 1997
The extracellular glycoprotein SPARC interacts with platelet-derived growth factor (PDGF)-AB and-BB and inhibits the binding of PDGF to its receptors.
EW Raines, TF Lane, ML Iruela-Arispe, R Ross, EH Sage
Proceedings of the National Academy of Sciences 89 (4), 1281-1285, 1992
The chicken chorioallantoic membrane model in biology, medicine and bioengineering
P Nowak-Sliwinska, T Segura, ML Iruela-Arispe
Angiogenesis 17, 779-804, 2014
Endostatin: yeast production, mutants, and antitumor effect in renal cell carcinoma
M Dhanabal, R Ramchandran, R Volk, IE Stillman, M Lombardo, ...
Cancer Research 59 (1), 189-197, 1999
Inhibition of angiogenesis by thrombospondin-1 is mediated by 2 independent regions within the type 1 repeats
ML Iruela-Arispe, M Lombardo, HC Krutzsch, J Lawler, DD Roberts
Circulation 100 (13), 1423-1431, 1999
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