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Duncan Jodrell
Duncan Jodrell
Professor of Cancer Therapeutics, University of Cambridge
Bestätigte E-Mail-Adresse bei cam.ac.uk - Startseite
Titel
Zitiert von
Zitiert von
Jahr
Targeting CXCL12 from FAP-expressing carcinoma-associated fibroblasts synergizes with anti–PD-L1 immunotherapy in pancreatic cancer
C Feig, JO Jones, M Kraman, RJB Wells, A Deonarine, DS Chan, ...
Proceedings of the National Academy of Sciences 110 (50), 20212-20217, 2013
17632013
Capecitabine as adjuvant treatment for stage III colon cancer
C Twelves, A Wong, MP Nowacki, M Abt, H Burris III, A Carrato, J Cassidy, ...
New England Journal of Medicine 352 (26), 2696-2704, 2005
16732005
Hyaluronan impairs vascular function and drug delivery in a mouse model of pancreatic cancer
MA Jacobetz, DS Chan, A Neesse, TE Bapiro, N Cook, KK Frese, C Feig, ...
Gut 62 (1), 112-120, 2013
11042013
Inhibition of cancer cell growth by ruthenium (II) arene complexes
RE Morris, RE Aird, P del Socorro Murdoch, H Chen, J Cummings, ...
Journal of medicinal chemistry 44 (22), 3616-3621, 2001
9072001
In vitro and in vivo activity and cross resistance profiles of novel ruthenium (II) organometallic arene complexes in human ovarian cancer
RE Aird, J Cummings, AA Ritchie, M Muir, RE Morris, H Chen, PJ Sadler, ...
British journal of cancer 86 (10), 1652-1657, 2002
7232002
Combenefit: an interactive platform for the analysis and visualization of drug combinations
GY Di Veroli, C Fornari, D Wang, S Mollard, JL Bramhall, FM Richards, ...
Bioinformatics 32 (18), 2866-2868, 2016
5912016
Structure− activity relationships for cytotoxic ruthenium (II) arene complexes containing N, N-, N, O-, and O, O-chelating ligands
A Habtemariam, M Melchart, R Fernández, S Parsons, IDH Oswald, ...
Journal of medicinal chemistry 49 (23), 6858-6868, 2006
5452006
Relationships between carboplatin exposure and tumor response and toxicity in patients with ovarian cancer.
DI Jodrell, MJ Egorin, RM Canetta, P Langenberg, EP Goldbloom, ...
Journal of clinical oncology 10 (4), 520-528, 1992
4631992
nab-Paclitaxel Potentiates Gemcitabine Activity by Reducing Cytidine Deaminase Levels in a Mouse Model of Pancreatic Cancer
KK Frese, A Neesse, N Cook, TE Bapiro, MP Lolkema, DI Jodrell, ...
Cancer discovery 2 (3), 260-269, 2012
4602012
Oral capecitabine as an alternative to iv 5-fluorouracil-based adjuvant therapy for colon cancer: safety results of a randomized, phase III trial
W Scheithauer, J McKendrick, S Begbie, M Borner, WI Burns, HA Burris, ...
Annals of Oncology 14 (12), 1735-1743, 2003
3582003
Controlling ligand substitution reactions of organometallic complexes: Tuning cancer cell cytotoxicity
F Wang, A Habtemariam, EPL van der Geer, R Fernández, M Melchart, ...
Proceedings of the National Academy of Sciences 102 (51), 18269-18274, 2005
3352005
Phase II studies of polymer-doxorubicin (PK1, FCE28068) in the treatment of breast, lung and colorectal cancer
LW Seymour, DR Ferry, DJ Kerr, D Rea, M Whitlock, R Poyner, C Boivin, ...
International journal of oncology 34 (6), 1629-1636, 2009
3332009
Tumor-induced IL-6 reprograms host metabolism to suppress anti-tumor immunity
TR Flint, T Janowitz, CM Connell, EW Roberts, AE Denton, AP Coll, ...
Cell metabolism 24 (5), 672-684, 2016
3092016
Tuning the reactivity of osmium (II) and ruthenium (II) arene complexes under physiological conditions
AFA Peacock, A Habtemariam, R Fernández, V Walland, FPA Fabbiani, ...
Journal of the American Chemical Society 128 (5), 1739-1748, 2006
2932006
CTGF antagonism with mAb FG-3019 enhances chemotherapy response without increasing drug delivery in murine ductal pancreas cancer
A Neesse, KK Frese, TE Bapiro, T Nakagawa, MD Sternlicht, TW Seeley, ...
Proceedings of the National Academy of Sciences 110 (30), 12325-12330, 2013
2682013
Loss of P53 function activates JAK2–STAT3 signaling to promote pancreatic tumor growth, stroma modification, and gemcitabine resistance in mice and is associated with patient …
SM Wörmann, L Song, J Ai, KN Diakopoulos, MU Kurkowski, K Görgülü, ...
Gastroenterology 151 (1), 180-193. e12, 2016
2412016
A randomised comparison between 6 months of bolus fluorouracil/leucovorin and 12 weeks of protracted venous infusion fluorouracil as adjuvant treatment in colorectal cancer
I Chau, AR Norman, D Cunningham, D Tait, PJ Ross, T Iveson, M Hill, ...
Annals of Oncology 16 (4), 549-557, 2005
2302005
A clinical study assessing the tolerability and biological effects of infliximab, a TNF-α inhibitor, in patients with advanced cancer
ER Brown, KA Charles, SA Hoare, RL Rye, DI Jodrell, RE Aird, R Vora, ...
Annals of oncology 19 (7), 1340-1346, 2008
2112008
Fibroblast drug scavenging increases intratumoural gemcitabine accumulation in murine pancreas cancer
E Hessmann, MS Patzak, L Klein, N Chen, V Kari, I Ramu, TE Bapiro, ...
Gut 67 (3), 497-507, 2018
2002018
CSF1R+ macrophages sustain pancreatic tumor growth through T cell suppression and maintenance of key gene programs that define the squamous subtype
JB Candido, JP Morton, P Bailey, AD Campbell, SA Karim, T Jamieson, ...
Cell reports 23 (5), 1448-1460, 2018
1982018
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