CCNF mutations in amyotrophic lateral sclerosis and frontotemporal dementia KL Williams, S Topp, S Yang, B Smith, JA Fifita, ST Warraich, KY Zhang, ... Nature communications 7 (1), 11253, 2016 | 221 | 2016 |
In vivo characterization of microglial engulfment of dying neurons in the zebrafish spinal cord M Morsch, R Radford, A Lee, EK Don, AP Badrock, TE Hall, NJ Cole, ... Frontiers in cellular neuroscience 9, 321, 2015 | 111 | 2015 |
Nucleo-cytoplasmic transport of TDP-43 studied in real time: impaired microglia function leads to axonal spreading of TDP-43 in degenerating motor neurons AJ Svahn, EK Don, AP Badrock, NJ Cole, MB Graeber, JJ Yerbury, ... Acta neuropathologica 136, 445-459, 2018 | 77 | 2018 |
Development and evolution of the muscles of the pelvic fin NJ Cole, TE Hall, EK Don, S Berger, CA Boisvert, C Neyt, R Ericsson, ... PLoS biology 9 (10), e1001168, 2011 | 69 | 2011 |
Microglia morphophysiological diversity and its implications for the CNS A Vidal-Itriago, RAW Radford, JA Aramideh, C Maurel, NM Scherer, ... Frontiers in immunology 13, 997786, 2022 | 62 | 2022 |
A Tol2 gateway-compatible toolbox for the study of the nervous system and neurodegenerative disease EK Don, I Formella, AP Badrock, TE Hall, M Morsch, E Hortle, A Hogan, ... Zebrafish 14 (1), 69-72, 2017 | 60 | 2017 |
STIM1 is required for remodeling of the endoplasmic reticulum and microtubule cytoskeleton in steering growth cones M Pavez, AC Thompson, HJ Arnott, CB Mitchell, I D'Atri, EK Don, ... Journal of Neuroscience 39 (26), 5095-5114, 2019 | 51 | 2019 |
Pathogenic mutation in the ALS/FTD gene, CCNF, causes elevated Lys48-linked ubiquitylation and defective autophagy A Lee, SL Rayner, SSL Gwee, A De Luca, H Shahheydari, ... Cellular and molecular life sciences 75, 335-354, 2018 | 51 | 2018 |
Expression of ALS/FTD-linked mutant CCNF in zebrafish leads to increased cell death in the spinal cord and an aberrant motor phenotype AL Hogan, EK Don, SL Rayner, A Lee, AS Laird, M Watchon, C Winnick, ... Human molecular genetics 26 (14), 2616-2626, 2017 | 46 | 2017 |
The evolutionary history of the development of the pelvic fin/hindlimb EK Don, PD Currie, NJ Cole Journal of Anatomy 222 (1), 114-133, 2013 | 42 | 2013 |
Real-time visualization of oxidative stress-mediated neurodegeneration of individual spinal motor neurons in vivo I Formella, AJ Svahn, RAW Radford, EK Don, NJ Cole, A Hogan, A Lee, ... Redox Biology 19, 226-234, 2018 | 40 | 2018 |
Kynurenine 3-monooxygenase activity in human primary neurons and effect on cellular bioenergetics identifies new neurotoxic mechanisms G Castellano-Gonzalez, KR Jacobs, E Don, NJ Cole, S Adams, CK Lim, ... Neurotoxicity Research 35, 530-541, 2019 | 35 | 2019 |
Dual Transcriptomics of Host-Pathogen Interaction of Cystic Fibrosis Isolate Pseudomonas aeruginosa PASS1 With Zebrafish SS Kumar, JI Tandberg, A Penesyan, LDH Elbourne, N Suarez-Bosche, ... Frontiers in cellular and infection microbiology 8, 406, 2018 | 29 | 2018 |
Mutant human FUS Is ubiquitously mislocalized and generates persistent stress granules in primary cultured transgenic zebrafish cells JR Acosta, C Goldsbury, C Winnick, AP Badrock, ST Fraser, AS Laird, ... PLoS One 9 (6), e90572, 2014 | 29 | 2014 |
Casein kinase II phosphorylation of cyclin F at serine 621 regulates the Lys48-ubiquitylation E3 ligase activity of the SCF(cyclin F) complex A Lee, SL Rayner, A De Luca, SSL Gwee, M Morsch, V Sundaramoorthy, ... Open biology 7 (10), 170058, 2017 | 28 | 2017 |
Genetic basis of hindlimb loss in a naturally occurring vertebrate model EK Don, TA de Jong-Curtain, K Doggett, TE Hall, B Heng, AP Badrock, ... Biology open 5 (3), 359-366, 2016 | 28 | 2016 |
The redox activity of protein disulfide isomerase inhibits ALS phenotypes in cellular and zebrafish models S Parakh, S Shadfar, ER Perri, AMG Ragagnin, CV Piattoni, MB Fogolín, ... Iscience 23 (5), 2020 | 22 | 2020 |
Aurora kinase B regulates axonal outgrowth and regeneration in the spinal motor neurons of developing zebrafish SSL Gwee, RAW Radford, S Chow, MD Syal, M Morsch, I Formella, A Lee, ... Cellular and molecular life sciences 75, 4269-4285, 2018 | 20 | 2018 |
Motor neuron abnormalities correlate with impaired movement in zebrafish that express mutant superoxide dismutase 1 KJ Robinson, KC Yuan, EK Don, AL Hogan, CG Winnick, MC Tym, ... Zebrafish 16 (1), 8-14, 2019 | 18 | 2019 |
Triggering cell stress and death using conventional UV laser confocal microscopy M Morsch, RAW Radford, EK Don, A Lee, E Hortle, NJ Cole, RS Chung JoVE (Journal of Visualized Experiments), e54983, 2017 | 18 | 2017 |