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Simon Vyse
Simon Vyse
Verified email at icr.ac.uk
Title
Cited by
Cited by
Year
Rare epidermal growth factor receptor (EGFR) mutations in non-small cell lung cancer
PT Harrison, S Vyse, PH Huang
Seminars in cancer biology 61, 167-179, 2020
4042020
Targeting EGFR exon 20 insertion mutations in non-small cell lung cancer
S Vyse, PH Huang
Signal transduction and targeted therapy 4 (1), 5, 2019
3222019
UBE2L3 polymorphism amplifies NF-κB activation and promotes plasma cell development, linking linear ubiquitination to multiple autoimmune diseases
MJ Lewis, S Vyse, AM Shields, S Boeltz, PA Gordon, TD Spector, ...
The American Journal of Human Genetics 96 (2), 221-234, 2015
992015
Primary cilia mediate diverse kinase inhibitor resistance mechanisms in cancer
AD Jenks, S Vyse, JP Wong, E Kostaras, D Keller, T Burgoyne, ...
Cell reports 23 (10), 3042-3055, 2018
842018
Dual targeting of PDGFRα and FGFR1 displays synergistic efficacy in malignant rhabdoid tumors
JP Wong, JR Todd, MA Finetti, F McCarthy, M Broncel, S Vyse, ...
Cell reports 17 (5), 1265-1275, 2016
522016
De novo mutations implicate novel genes in systemic lupus erythematosus
V Pullabhatla, AL Roberts, MJ Lewis, D Mauro, DL Morris, CA Odhams, ...
Human molecular genetics 27 (3), 421-429, 2018
442018
Exploiting receptor tyrosine kinase co-activation for cancer therapy
AC Tan, S Vyse, PH Huang
Drug discovery today 22 (1), 72-84, 2017
402017
Three‐dimensional modelling identifies novel genetic dependencies associated with breast cancer progression in the isogenic MCF10 model
SL Maguire, B Peck, PT Wai, J Campbell, H Barker, A Gulati, F Daley, ...
The Journal of Pathology 240 (3), 315-328, 2016
392016
Systematic analysis of tumour cell-extracellular matrix adhesion identifies independent prognostic factors in breast cancer
JR Todd, KA Ryall, S Vyse, JP Wong, RC Natrajan, Y Yuan, AC Tan, ...
Oncotarget 7 (39), 62939, 2016
372016
Quantitative phosphoproteomic analysis of acquired cancer drug resistance to pazopanib and dasatinib
S Vyse, F McCarthy, M Broncel, A Paul, JP Wong, A Bhamra, PH Huang
Journal of proteomics 170, 130-140, 2018
322018
Improved monitoring of clinical response in Systemic Lupus Erythematosus by longitudinal trend in soluble vascular cell adhesion molecule-1
MJ Lewis, S Vyse, AM Shields, L Zou, M Khamashta, PA Gordon, ...
Arthritis research & therapy 18, 1-11, 2016
292016
Advances in mass spectrometry based strategies to study receptor tyrosine kinases
S Vyse, H Desmond, PH Huang
IUCrJ 4 (2), 119-130, 2017
212017
Next-generation sequencing for the management of sarcomas with no known driver mutations
S Vyse, K Thway, PH Huang, RL Jones
Current Opinion in Oncology 33 (4), 315-322, 2021
192021
Tackling drug resistance in EGFR exon 20 insertion mutant lung cancer
L Pacini, AD Jenks, S Vyse, CP Wilding, A Arthur, PH Huang
Pharmacogenomics and personalized medicine, 301-317, 2021
192021
Amivantamab for the treatment of EGFR exon 20 insertion mutant non-small cell lung cancer
S Vyse, PH Huang
Expert Review of Anticancer Therapy 22 (1), 3-16, 2022
182022
Exploiting synthetic lethality and network biology to overcome EGFR inhibitor resistance in lung cancer
S Vyse, A Howitt, PH Huang
Journal of molecular biology 429 (12), 1767-1786, 2017
182017
Effect of UBE2L3 genotype on regulation of the linear ubiquitin chain assembly complex in systemic lupus erythematosus
M Lewis, S Vyse, A Shields, S Boeltz, P Gordon, T Spector, P Lehner, ...
The Lancet 385, S9, 2015
172015
Targeting EGFR exon 20 insertions in non-small cell lung cancer by exploiting a dependency on parallel SRC signalling
S Vyse, N Chen, J Oddy, P Harrison, A Le, A Estrada-Bernal, M Hermsen, ...
Annals of Oncology 30, vii3, 2019
2019
De novo mutations implicate novel genes with burden of rare variants in Systemic Lupus Erythematosus
V Pullabhatla, AL Roberts, MJ Lewis, D Mauro, DL Morris, CA Odhams, ...
bioRxiv, 139238, 2017
2017
OP0232 C1qtnf4 Mutation Identified by Exome Sequencing Is Associated with Systemic Lupus Erythematosus and Dysregulation of Tnf-Induced Apoptosis
D Mauro, MJ Lewis, V Pullabhatla, S Vyse, M Simpson, ...
Annals of the Rheumatic Diseases 75 (Suppl 2), 145-146, 2016
2016
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Articles 1–20