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Isidro Cortés Ciriano
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Year
Comprehensive characterization of cancer driver genes and mutations
MH Bailey, C Tokheim, E Porta-Pardo, S Sengupta, D Bertrand, ...
Cell 173 (2), 371-385. e18, 2018
16052018
Pan-cancer analysis of whole genomes
Nature 578 (7793), 82-93, 2020
9372020
Patterns of somatic structural variation in human cancer genomes
Y Li, ND Roberts, JA Wala, O Shapira, SE Schumacher, K Kumar, ...
Nature 578 (7793), 112-121, 2020
4232020
A molecular portrait of microsatellite instability across multiple cancers
I Cortes-Ciriano, S Lee, WY Park, TM Kim, PJ Park
Nature communications 8 (1), 1-12, 2017
4042017
Analyses of non-coding somatic drivers in 2,658 cancer whole genomes
E Rheinbay, MM Nielsen, F Abascal, JA Wala, O Shapira, G Tiao, ...
Nature 578 (7793), 102-111, 2020
3342020
Comprehensive analysis of chromothripsis in 2,658 human cancers using whole-genome sequencing
I Cortes-Ciriano, JK Lee, R Xi, D Jain, YL Jung, L Yang, D Gordenin, ...
Nature Genetics 52, 331–341, 2020
3192020
Mechanisms and therapeutic implications of hypermutation in gliomas
M Touat, YY Li, AN Boynton, LF Spurr, JB Iorgulescu, CL Bohrson, ...
Nature 580 (7804), 517-523, 2020
2672020
Perspective on oncogenic processes at the end of the beginning of cancer genomics
L Ding, MH Bailey, E Porta-Pardo, V Thorsson, A Colaprico, D Bertrand, ...
Cell 173 (2), 305-320. e10, 2018
2612018
Community assessment to advance computational prediction of cancer drug combinations in a pharmacogenomic screen
MP Menden, D Wang, MJ Mason, B Szalai, KC Bulusu, Y Guan, T Yu, ...
Nature communications 10 (1), 1-17, 2019
219*2019
Intersection of diverse neuronal genomes and neuropsychiatric disease: The Brain Somatic Mosaicism Network
MJ McConnell, JV Moran, A Abyzov, S Akbarian, T Bae, I Cortes-Ciriano, ...
Science 356 (6336), eaal1641, 2017
2142017
Pan-cancer analysis of whole genomes identifies driver rearrangements promoted by LINE-1 retrotransposition
B Rodriguez-Martin, EG Alvarez, A Baez-Ortega, J Zamora, F Supek, ...
Nature genetics 52 (3), 306-319, 2020
2092020
Genomic basis for RNA alterations in cancer
C Calabrese, NR Davidson, D Demircioğlu, NA Fonseca, Y He, A Kahles, ...
Nature 578 (7793), 129-136, 2020
1982020
Pan-cancer analysis of whole genomes.
S Hirano, L Yang, M Juul, CA Purdie, BP O'Neill, R Kabbe, ...
Nature 578 (DKFZ-2020-01051), 82-93, 2020
1422020
Detecting the mutational signature of homologous recombination deficiency in clinical samples
DC Gulhan, JJK Lee, GEM Melloni, I Cortés-Ciriano, PJ Park
Nature genetics 51 (5), 912-919, 2019
1302019
Disruption of chromatin folding domains by somatic genomic rearrangements in human cancer
KC Akdemir, VT Le, S Chandran, Y Li, RG Verhaak, R Beroukhim, ...
Nature genetics 52 (3), 294-305, 2020
1262020
Polypharmacology modelling using proteochemometrics (PCM): recent methodological developments, applications to target families, and future prospects
I Cortés-Ciriano, QU Ain, V Subramanian, EB Lenselink, O Méndez-Lucio, ...
MedChemComm 6 (1), 24-50, 2015
1042015
Improved large-scale prediction of growth inhibition patterns using the NCI60 cancer cell line panel
I Cortés-Ciriano, GJP Van Westen, G Bouvier, M Nilges, JP Overington, ...
Bioinformatics 32 (1), 85-95, 2016
972016
The Impact of Environmental and Endogenous Damage on Somatic Mutation Load in Human Skin Fibroblasts
DAG Natalie Saini, Steven A. Roberts, Leszek J. Klimczak, Kin Chan, Sara A ...
PloS Genetics, 2016
86*2016
Reconstructing the lineage histories and differentiation trajectories of individual cancer cells in myeloproliferative neoplasms
D Van Egeren, J Escabi, M Nguyen, S Liu, CR Reilly, S Patel, B Kamaz, ...
Cell stem cell 28 (3), 514-523. e9, 2021
82*2021
Artificial intelligence in drug discovery: what is realistic, what are illusions? Part 1: ways to make an impact, and why we are not there yet
A Bender, I Cortés-Ciriano
Drug discovery today 26 (2), 511-524, 2021
812021
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Articles 1–20