Sabrina Spencer
Sabrina Spencer
University of Colorado-Boulder (Assistant Prof); Stanford University (Postdoc); MIT (PhD)
Verified email at - Homepage
Cited by
Cited by
Non-genetic origins of cell-to-cell variability in TRAIL-induced apoptosis
SL Spencer, S Gaudet, JG Albeck, JM Burke, PK Sorger
Nature 459 (7245), 428-432, 2009
The proliferation-quiescence decision is controlled by a bifurcation in CDK2 activity at mitotic exit
SL Spencer, SD Cappell, FC Tsai, KW Overton, CL Wang, T Meyer
Cell 155 (2), 369-383, 2013
Measuring and modeling apoptosis in single cells
SL Spencer, PK Sorger
Cell 144 (6), 926-939, 2011
Modeling a snap-action, variable-delay switch controlling extrinsic cell death
JG Albeck, JM Burke, SL Spencer, DA Lauffenburger, PK Sorger
PLoS Biol 6 (12), e299, 2008
Non-genetic cell-to-cell variability and the consequences for pharmacology
M Niepel, SL Spencer, PK Sorger
Current opinion in chemical biology 13 (5-6), 556-561, 2009
Ki67 is a graded rather than a binary marker of proliferation versus quiescence
I Miller, M Min, C Yang, C Tian, S Gookin, D Carter, SL Spencer
Cell reports 24 (5), 1105-1112. e5, 2018
Irreversible APCCdh1 inactivation underlies the point of no return for cell-cycle entry
SD Cappell, M Chung, A Jaimovich, SL Spencer, T Meyer
Cell 166 (1), 167-180, 2016
Modeling somatic evolution in tumorigenesis
SL Spencer, RA Gerety, KJ Pienta, S Forrest
PLoS Comput Biol 2 (8), e108, 2006
Synthesis: cancer research meets evolutionary biology
JW Pepper, C Scott Findlay, R Kassen, SL Spencer, CC Maley
Evolutionary applications 2 (1), 62-70, 2009
Endogenous replication stress in mother cells leads to quiescence of daughter cells
M Arora, J Moser, H Phadke, AA Basha, SL Spencer
Cell reports 19 (7), 1351-1364, 2017
An ordinary differential equation model for the multistep transformation to cancer
SL Spencer, MJ Berryman, JA García, D Abbott
Journal of Theoretical Biology 231 (4), 515-524, 2004
Exploring the contextual sensitivity of factors that determine cell-to-cell variability in receptor-mediated apoptosis
S Gaudet, SL Spencer, WW Chen, PK Sorger
PLoS Comput Biol 8 (4), e1002482, 2012
Cells surviving fractional killing by TRAIL exhibit transient but sustainable resistance and inflammatory phenotypes
DA Flusberg, J Roux, SL Spencer, PK Sorger
Molecular biology of the cell 24 (14), 2186-2200, 2013
Basal p21 controls population heterogeneity in cycling and quiescent cell cycle states
KW Overton, SL Spencer, WL Noderer, T Meyer, CL Wang
Proceedings of the National Academy of Sciences 111 (41), E4386-E4393, 2014
Control of the Restriction Point by Rb and p21
J Moser, I Miller, D Carter, SL Spencer
Proceedings of the National Academy of Sciences 115 (35), E8219-E8227, 2018
A map of protein dynamics during cell-cycle progression and cell-cycle exit
S Gookin, M Min, H Phadke, M Chung, J Moser, I Miller, D Carter, ...
PLoS biology 15 (9), e2003268, 2017
Systematic calibration of a cell signaling network model
KA Kim, SL Spencer, JG Albeck, JM Burke, PK Sorger, S Gaudet, DH Kim
BMC bioinformatics 11 (1), 202, 2010
p53 suppresses muscle differentiation at the myogenin step in response to genotoxic stress
WCL Yang ZJ, Broz DK, Noderer WL, Ferreira JP, Overton KW, Spencer SL, Meyer ...
Cell Death and Differentiation 22 (4), 560-73, 2015
Temporal integration of mitogen history in mother cells controls proliferation of daughter cells
M Min, Y Rong, C Tian, SL Spencer
Science 368 (6496), 1261-1265, 2020
Spontaneously slow-cycling subpopulations of human cells originate from activation of stress-response pathways
M Min, SL Spencer
PLoS biology 17 (3), e3000178, 2019
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