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joseph quinn
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Genetic meta-analysis of diagnosed Alzheimer’s disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing
BW Kunkle, B Grenier-Boley, R Sims, JC Bis, V Damotte, AC Naj, ...
Nature genetics 51 (3), 414-430, 2019
21662019
Common variants at MS4A4/MS4A6E, CD2AP, CD33 and EPHA1 are associated with late-onset Alzheimer's disease
AC Naj, G Jun, GW Beecham, LS Wang, BN Vardarajan, J Buros, ...
Nature genetics 43 (5), 436-441, 2011
21342011
The ageing systemic milieu negatively regulates neurogenesis and cognitive function
SA Villeda, J Luo, KI Mosher, B Zou, M Britschgi, G Bieri, TM Stan, ...
Nature 477 (7362), 90-94, 2011
18232011
Analysis of shared heritability in common disorders of the brain
Brainstorm Consortium, V Anttila, B Bulik-Sullivan, HK Finucane, ...
Science 360 (6395), eaap8757, 2018
13632018
Mitochondria are a direct site of Aβ accumulation in Alzheimer's disease neurons: implications for free radical generation and oxidative damage in disease progression
M Manczak, TS Anekonda, E Henson, BS Park, J Quinn, PH Reddy
Human molecular genetics 15 (9), 1437-1449, 2006
13432006
Classification and prediction of clinical Alzheimer's diagnosis based on plasma signaling proteins
S Ray, M Britschgi, C Herbert, Y Takeda-Uchimura, A Boxer, K Blennow, ...
Nature medicine 13 (11), 1359-1362, 2007
12772007
Rare coding variants in PLCG2, ABI3, and TREM2 implicate microglial-mediated innate immunity in Alzheimer's disease
R Sims, SJ Van Der Lee, AC Naj, C Bellenguez, N Badarinarayan, ...
Nature genetics 49 (9), 1373-1384, 2017
8982017
Docosahexaenoic acid supplementation and cognitive decline in Alzheimer disease: a randomized trial
JF Quinn, R Raman, RG Thomas, K Yurko-Mauro, EB Nelson, C Van Dyck, ...
Jama 304 (17), 1903-1911, 2010
8872010
DJ-1 and α-synuclein in human cerebrospinal fluid as biomarkers of Parkinson’s disease
Z Hong, M Shi, KA Chung, JF Quinn, ER Peskind, D Galasko, J Jankovic, ...
Brain 133 (3), 713-726, 2010
7252010
Plasma exosomal α-synuclein is likely CNS-derived and increased in Parkinson’s disease
M Shi, C Liu, TJ Cook, KM Bullock, Y Zhao, C Ginghina, Y Li, P Aro, ...
Acta neuropathologica 128, 639-650, 2014
6102014
Lipid peroxidation in aging brain and Alzheimer’s disease
TJ Montine, MD Neely, JF Quinn, MF Beal, WR Markesbery, LJ Roberts II, ...
Free Radical Biology and Medicine 33 (5), 620-626, 2002
5592002
Meta-analysis confirms CR1, CLU, and PICALM as alzheimer disease risk loci and reveals interactions with APOE genotypes
G Jun, AC Naj, GW Beecham, LS Wang, J Buros, PJ Gallins, JD Buxbaum, ...
Archives of neurology 67 (12), 1473-1484, 2010
4962010
YKL-40: a novel prognostic fluid biomarker for preclinical Alzheimer's disease
R Craig-Schapiro, RJ Perrin, CM Roe, C Xiong, D Carter, NJ Cairns, ...
Biological psychiatry 68 (10), 903-912, 2010
4902010
Cerebrospinal fluid biomarkers for Parkinson disease diagnosis and progression
M Shi, J Bradner, AM Hancock, KA Chung, JF Quinn, ER Peskind, ...
Annals of neurology 69 (3), 570-580, 2011
4742011
Detection of biomarkers with a multiplex quantitative proteomic platform in cerebrospinal fluid of patients with neurodegenerative disorders
F Abdi, JF Quinn, J Jankovic, M McIntosh, JB Leverenz, E Peskind, ...
Journal of Alzheimer's Disease 9 (3), 293-348, 2006
4682006
Cerebrospinal fluid tau and β-amyloid: how well do these biomarkers reflect autopsy-confirmed dementia diagnoses?
CM Clark, S Xie, J Chittams, D Ewbank, E Peskind, D Galasko, JC Morris, ...
Archives of neurology 60 (12), 1696-1702, 2003
4652003
Neuropathological and genetic correlates of survival and dementia onset in synucleinopathies: a retrospective analysis
DJ Irwin, M Grossman, D Weintraub, HI Hurtig, JE Duda, SX Xie, EB Lee, ...
The Lancet Neurology 16 (1), 55-65, 2017
4442017
Phase 2 safety trial targeting amyloid β production with a γ-secretase inhibitor in Alzheimer disease
AS Fleisher, R Raman, ER Siemers, L Becerra, CM Clark, RA Dean, ...
Archives of neurology 65 (8), 1031-1038, 2008
4332008
Association of perivascular localization of aquaporin-4 with cognition and Alzheimer disease in aging brains
DM Zeppenfeld, M Simon, JD Haswell, D D’Abreo, C Murchison, JF Quinn, ...
JAMA neurology 74 (1), 91-99, 2017
4302017
Amyloid beta peptides in human plasma and tissues and their significance for Alzheimer's disease
AE Roher, CL Esh, TA Kokjohn, EM Castaño, GD Van Vickle, WM Kalback, ...
Alzheimer's & Dementia 5 (1), 18-29, 2009
4282009
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